Explore evolutionary relationships at the molecular level using DNA or protein. Students investigate the difference of DNA sequences or proteins of closely related species.

![]() Comparative Proteomics Kit I |
![]() DNA Barcoding Kits |
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Overview |
In this proteomics based lab, students analyze the differences of the actin and myosin muscle proteins to build an understanding that even closely related species exhibit considerable variation. |
Investigate the nuances of the cytochrome c oxidase I (COI) gene or the internal transcribed spacer (ITS) of your choice of fish, mammals, insects, or fungi. Investigate fraud happening at local marketplaces or explore species variations in local habitats. |
Ideal For | Teachers who want to explore evolutionary relationships by examining fish muscle proteins and want to include protein gel electrophoresis (SDS-PAGE) in their classrooms | Teachers who want to introduce students to PCR, gel electrophoresis, DNA sequencing, bioinformatics, and potentially citizen science projects |
AP Alignment | ||
Pedagogical Support | 20 Questions to Master Inquiry - Protein Profiler Kit | Fish DNA Barcoding Kit Planning Guide, Biotechnology Explorer |
Class Sessions | Three 45 minute classes | Varies |
Inquiry Type | Open-ended | Open-ended |
Required Equipment |
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