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This section offers extensive technical information to guide you through your research and help you overcome obstacles in your experiments. Here you will find workflows, protocols, FAQs, videos and product demonstrations, and a wealth of technical information on the theory and principles behind important and cutting-edge life science technologies.

Therapeutic Discovery & Development

  • Cancer cells getting destroyed

    CAR-T Cell Therapy Development

    CAR-T cell therapy development is complex, in part because CAR-T cells are living biological systems that require a custom R&D approach.

  • Therapeutic Antibody Development

    Therapeutic Antibody Development

    Antibody-based therapeutics manage and treat various cancers, inflammation diseases, and viral infections. Learn about workflows where antibodies are central to many analytical assays and clinical diagnostics.

  • Viral Vector Vaccine Development

    Viral Vector Vaccine Development

    The COVID-19 pandemic opened the door to expedited vaccine development using new technologies and therapies that have traditionally been used in other applications.

  • Cancer Immunotherapy Development

    Learn about trends in cancer immunotherapy development, such as CAR-T, and tools for genomic, cellular, and proteomic research.

  • Biologic Development

    Biologic Development

    Biologic development brings patients closer to personalized medicine to treat health problems.

  • Biomarker Discovery

    Biomarker Discovery & Validation

    Biomarker monitoring across drug discovery, development, and clinical stages is key to defining drug effects.

  • Biosimilar Development

    Biosimilar Development

    Biosimilar development requires physicochemical and functional characterization to ensure similarity.

  • CRISPR Gene Editing

    CRISPR Gene Editing

    CRISPR enables researchers to edit their desired target genes efficiently and accelerate drug development.

  • Drug Discovery and Development

    Drug Discovery and Development

    Bio-Rad products and services span the entire range of drug discovery and development activities, from target identification to scale-up and manufacturing.

Genomics & Gene Expression

  • Genomics

    PCR (Polymerase Chain Reaction)

    Learn how PCR works, how to choose the right PCR instrument, how to design, optimize, analyze, and troubleshoot PCR assays.

  • Real-Time PCR (qPCR)

    Discover an array of solutions to optimize, execute, and troubleshoot MIQE-compliant real-time PCR experiments.

  • Introduction to Digital PCR

    Digital PCR is a breakthrough technology that provides ultrasensitive and absolute nucleic acid quantification.

  • Genomics

    Explore different aspects of genomics — from functional genomics and biomarker discovery to mutation analysis, gene expression, transfection, and epigenetics.

  • Targeted Genome Editing

    Learn about the major systems for targeted genome editing, including CRISPR/Cas9, some key applications, and workflow options.

  • Horizontal Electrophoresis

    Gel boxes, running buffers, available agarose types, as well as factors affecting resolution of DNA fragments, to help with agarose gel electrophoresis of DNA.

  • Pulsed Field Gel Electrophoresis

    How can large DNA fragments be separated using PFGE? How to prepare plugs, optimize sample resolution, analyze images, and troubleshoot PFGE gels? Explore.

  • ddPCR Master Class Videos

    Become an expert in all things ddPCR. Our master class sessions allow you to learn from the best in the field. From instrument overviews to informational sessions highlighting the implications of ddPCR in the real world, Master Classes have it all.

Cell Biology & Biochemistry

  • Biomarker Analysis

    Details on how biomarkers such as hormones, cytokines, chemokines, growth factors, and phosphoproteins are used to investigate physiological or pharmacological mechanisms.

  • Stem Cell Research

    Tips for isolation, maintenance, differentiation, transfection, and analysis of stem cells.

  • Introduction to Transfection

    Information on electroporation, viral transfection vectors, lipofection, and biolistics transformation and tips on planning and selecting the appropriate transfection method.

  • Cell Counting Methods

    Manual and automated cell counting methods and their application to gene expression studies are presented and discussed here.

  • Multiplex Immunoassays

    Details on experimental design, data collection, analysis, and validation of multiplex protein assays using the Bio-Plex Suspension Array System.

Proteomics & Protein Purification

  • Introduction to Chromatography

    An overview of the various types of chromatography methods to help guide you in your protein purification experiments.

  • Protein Purification and Isolation

    Learn how protein purification by chromatography is used in monoclonal antibody discovery, viral contaminant removal, and preparative protein isolation.

  • Separation, Transfer, and Analysis of Proteins

    Bio-Rad’s V3 Western Workflow facilitates speed and validation at each step of a western blotting experiment — from running gels to quantifying proteins.

  • Introduction to Protein Electrophoresis

    Protocols, video tutorials, and selection guides to help you at every step of your electrophoresis experiments.

  • Western Blot Learning Center

    The Western Blot Learning Center is a complete reference on all of the steps of western blotting, includes practical theory, protocols, and recommendations on how to make your blots better from experts.

  • Fluorescent Western Blotting

    Learn how fluorescence western blotting and total protein normalization can help with quantitative and accurate protein expression analyses.

  • 2-D Electrophoresis

    Information on sample preparation and imaging of 2-D gels, plus protocols, demonstrations, video tutorials, and troubleshooting tips.

  • Imaging and Analysis

    Comparison of parameters, sensitivity, and data analysis using Bio-Rad imaging systems and software to determine which imaging system is ideal for your application.

Resources

  • Customer Support

    Download product documents, tech notes, and CoAs; view product support videos;
    contact Customer Care and Technical Support.