Translational Research: From Bench to Bedside

Develop a deeper understanding of disease biology including microenvironments, cellular morphology, and mechanisms of disease progression.

Validate your early discovery insights using multiple model systems and optimize your potential therapeutics for safety and efficacy.

Test your potential therapy in rigorous and regulated human clinical trials to analyze therapeutic efficacy, and potential side effects in both healthy and patient populations.

Begin large-scale manufacturing of your new therapeutic, while monitoring your processes and patients to ensure safety and the dissemination of appropriate treatment plans.

Analyzing genomic, proteomic, and cellular biomarkers provides vital information regarding safety and efficacy during drug discovery and development.

Biomarker monitoring through drug discovery, development, and clinical stages is key to defining disease progression and therapeutic response.

Because stem cells remain undifferentiated, maintain prolonged proliferation, and can differentiate into a variety of cell types, they have the potential to treat a variety of diseases.

Learn about the introduction of foreign DNA into bacterial and/or mammalian cells through this series covering transfection methods, efficiency, and protocols.

Learn about the precise, highly sensitive quantification of nucleic acids through this series covering ddPCR™ technology, applications, and experiment planning.

Even though chromatography has been in use for over a century, protein purification is a challenging and evolving technique due to the structures, properties, and quantities of proteins and their contaminants.

Real-time PCR can be used for both qualitative and quantitative analysis and allows you to determine the initial number of copies of template DNA with accuracy and high sensitivity over a wide dynamic range.