ZOE™ Fluorescent Cell Imager

ZOE Fluorescent Cell Imager

The ZOE Fluorescent Cell Imager eliminates the complexities of cell imaging associated with traditional microscopes. This fluorescence imaging system combines the ease of use of a personal tablet with the power of an inverted microscope.

An Android-based platform, the ZOE Cell Imager uses an intuitive touch-screen interface to control the brightfield, three fluorescence channels, and the integrated digital camera.

The ZOE Fluorescent Cell Imager is a complete digital imaging system, allowing users to view samples, capture and store images, and create multicolor overlays. Thanks to the built-in light shield, the ZOE Cell Imager does not require a darkroom for fluorescence imaging.

Take the ZOE Imager for a Test Drive

Launch the ZOE Interactive Web App to try the intuitive ZOE user interface, manipulate images, view features and specifications in depth, and more.
Launch ZOE Interactive Web App

Features and Benefits of the ZOE Fluorescent Cell Imager

  • Simplified cell imaging — the intuitive touch-screen interface allows users to view cells, capture images, and create multichannel merges with minimal training
  • Flexible operation — brightfield and three fluorescence channels enable use for routine cell culture applications and more sophisticated imaging applications
  • Fluorescence imaging at your bench — light shield permits fluorescence imaging in ambient light
  • Robust construction — fully integrated system with long-life LEDs, ready for intensive daily use
  • LED light sources — thousands of hours of illumination that are instantly ready after power-on
  • Large viewing area — the motorized stage and wide field of view allow you to see more of your sample, faster
  • Small footprint — compact size accommodates crowded lab benches

Learn more about the features of the ZOE Cell Imager.

Applications of the ZOE Fluorescent Cell Imager

Use the ZOE Cell Imager to check/screen samples prior to high-content analysis (HCA), high-throughput screening (HCS), confocal imaging, or fluorescence-activated cell sorting (FACS). With a brightfield and three fluorescent channels, the ZOE Cell Imager has all the features needed for daily cell culture work as well as fluorescent applications:

  • Visual estimation of cell confluency
  • Observation of general cell health and morphology
  • Cell growth and proliferation monitoring
  • Capturing cell images (with or without fluorescent labels)
  • Visualization of expressed fluorescent proteins
  • Immunofluorescent protein localization
  • Estimation of transfection efficiency

Illumination Light Sources

  • Blue channel uses a UV LED
  • Green channel uses a blue LED
  • Red channel uses a green LED
  • Brightfield channel uses a ring of multiple green LEDs for reduced chromatic aberration

Fluorophores Compatible with the ZOE Fluorescent Cell Imaging System

This is not a comprehensive list; other dyes and fluorescent proteins with compatible excitation and emission spectra can also be used.

Blue Channel
Excitation: 355/40 nm
Emission: 433/36 nm
Green Channel
Excitation: 480/17 nm
Emission: 517/23 nm
Red Channel
Excitation: 556/20 nm
Emission: 615/61 nm
PureBlu™ DAPI Nuclear
Staining Dye
CytoTrack Green
ReadiLink 555/570
Antibody Labeling Kit
PureBlu Hoechst 33342
Nuclear Staining Dye
ReadiLink 492/516
Antibody Labeling Kit
ReadiLink 594/610
Antibody Labeling Kit
ReadiLink 350/440
Antibody Labeling Kit
VivaFix 498/521
Cell Viability Assay*
VivaFix 547/573
Cell Viability Assay
VivaFix™ 353/442
Cell Viability Assay
CFDA-SE VivaFix 583/603
Cell Viability Assay
Alexa Fluor 350 Acridine Orange Alexa Fluor 546
Alexa Fluor 405
Alexa Fluor 488 dye* Alexa Fluor 568
Cascade Blue BODIPY Fl* Alexa Fluor 594
CellTracker Blue Calcein AM Alexa Fluor 610
DAPI* DiO Cy3*
Hoechst* EGFP* Dil Stain
LysoTracker Blue ER-Tracker Green DsRed*
Marina Blue FITC* ER-Tracker Red
NucBlue Fixed MitoTracker Green FM mCherry*
NucBlue Live SYTO 9, SYTO 13, SYTO 16 mStrawberry
SYTOX Green MitoTracker Red*
Tubulin Green mKate*
SYTOX Orange
SYTO 84, SYTO 85
Texas Red*

* R&D Tested

Imaging channels Brightfield channel and 3 fluorescence channels (blue, green, and red)
Light source Blue channel: UV LED
Green channel: blue LED
Red channel: green LED
Brightfield channel: multiple green LEDs (reduces chromatic aberration)
User interface 10.1 in. color (26 cm) touch-screen LCD monitor, with anti-glare and anti-fingerprint treatment, 1,280 x 768 pixel image resolution, 80–180° angle tilt range
Focusing mechanism Coarse and fine, manual adjustment
Camera Monochrome camera, 12 bit CMOS, 5 megapixels
Data format JPEG, TIFF, or RAW image files
Image merge Images from up to 4 channels can be overlaid
Data storage 16 GB internal memory (~2,500 JPEG files,1,500 TIFF files, 400–800 RAW files)
Data export Yes, 2 USB ports
Display output Yes, 1 HDMI port
Objective 20x
Numerical aperture 0.40
Display magnification Standard: 175x; zoom: 700x
Maximum imaging area 0.70 mm2 field of view
Motorized stage 6 mm travel in X, Y direction, touch-screen control of travel speed and direction
Compatible with Flasks: T25, T75, or T225
Multiwell plates: 6-, 12-, 24-, 48-, 96-, or 384-well microplates
Dishes: 35 mm, 60 mm, or 100 mm
Slides: chamber slides or standard glass microscopy slides
Software Stand-alone Android operating system; PC is not required for operation
Instrument size (L x W x H) 33 x 32 x 30 cm (13 x 12.6 x 11.6 in.)
Instrument weight 9 kg (19.7 lb)

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ZOE™ Fluorescent Cell Imager

Stand-alone fluorescent cell imager, includes instrument, power supply, USB flash drive; 120–240 V

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Number Description Options
6585 ZOE™ Fluorescent Cell Imager Brochure, Rev A Click to download [ Add to Cart (Free) ]
10041704 ZOE™ Fluorescent Cell Imager Instruction Manual, Rev B Click to download
10041709 ZOE™ Fluorescent Cell Imager Quick Guide, Rev B Click to download
6685 ZOE: The Perfect Teaching Assistant Flier, Rev A Click to download