Genesis Cell Isolation System #CEL20101

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CEL20101 Genesis System

Overview

The Genesis Cell Isolation System is designed for automated selection and capture of 8µm-30µm cells by size. It includes an intuitive touch-screen interface, integrated reagent dispensing and slide temperature control.

Description

Description

The Genesis System with Celselect Slides™ enables automatic and efficient capture of cells from various liquid biopsies as well as other samples types for enrichment and enumeration applications. The slides utilize 56,400 individual microchambers to capture cells between 8-30 µm.

Features and Benefits

  • One System, Two Applications: Automated cell capture for enumeration or enrichment on the same system
  • Capture Mechanism: Capture cells based on size
  • Sample Processing: High capture efficiency without preprocessing
  • Customization: Genesis Protocol Builder Software Tool enables optimization for different samples types or antibody stains

Celselect Slides Enumeration/Immunolabeling Workflow

Sample is prepared with fixing reagent and loaded on to the instrument. Cells are captured and immunolabeled automatically in the Celselect Slides microchambers while smaller components (<8 µm) flow through the slide to waste. The Celselect Slide is imaged on an automated microscope and files can be imported for reporting.

Celselect Enumeration Workflow
Add fixing reagent to sample and load sample on to the instrument. Sample and staining reagents are prepped according to predefined protocols
Genesis System automates capture and immunolabeling on Celselect Slides
Image Celselect Slides on an automated microscope
Import files from microscope to Rare Cell Analysis Software, confirm cells of interest, and generate report

Celselect Slides Enrichment Workflow

Sample is prepared with the dilution buffer and loaded on to the instrument. Cells are captured automatically in the Celselect Slides while smaller components (<8 µm) flow through the slide to waste. Cells are recovered in a single tube for downstream analysis.

Celselect Enrichment Workflow
Add dilution buffer to sample and load sample on to the instrument
Genesis System automates capture and recovery of cells
Cells can be characterized with methods such as sequencing (bulk or single-cell), digital PCR, FISH, flow cytometry, or cells cultured for further in vitro and in vivo analysis

 

For applications which require protocol optimization or creation of new protocols for custom reagents or antibody labeling, the Genesis Protocol Builder Software Tool enables adjustment of parameters such as reagent dispensing, pump pressures, and incubation settings. Building custom protocols is performed on your local computer.

Included Components

  • Genesis System
  • Genesis Instrument Accessory Kit
  • Celselect Accessory Kit
  • Genesis System Software

Related Products

Specifications

Specifications

Sample input
4 ml
Parallel Sample Processing
2 samples
Cell Capture Technology
Microfluidics
Dimensions
Instrument open: 17.2” W x 23.0” D x 24” H
Instrument closed: 17.2” W x 23.0” D x 15.9” H
Open System
Flexibility to use alternative reagents, antibodies. Adjustable protocols parameters.

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