Cell Capture and Recovery

Add New Depth to Rare Cell Studies with the Efficiency, Ease, and Versatility of Celselect Slides™

The complexity of life is rooted in cells. From cell structure, to genetic variability, gene expression, and the formation of complex tissues and organs, all of biology is dependent upon this basic unit. The selection, capture, and study of cells, particularly rare cells, treated cells, or cells within a mixed cell population, is essential for providing insight into diverse areas such as the mechanisms of cancer and metastasis, disease, symbiosis, and biological diversity.

The Genesis Cell Isolation System with Celselect slides technology achieves fast, efficient selection and capture of viable individual cells 8-30 µm in size from liquid biopsy, cell culture, and other liquid sample types using gentle microfluidics and size-based, cell selection.

How Could Your Cell Research Benefit with Celselect Slides Technology?

Examine how the Genesis System with Celselect Slides™ can be used for efficient capture, recovery, and analysis of circulating tumor cells (CTCs) from liquid biopsy samples. Imagine what you can do with Celselect technology with your cells!

discover

advanced cell capture, recovery, and labeling or staining in an integrated workflow with the Genesis System and Celselect Slides™
Application: Circulating tumor cell (CTC) capture, enumeration and immunolabeling.

Celselect Workflow

Application: liquid biopsy CTC capture

flow

liquid biopsy samples over 140,800 individual micro chambers

capture

individual CTCs with precise, non-biased, gentle size selection that preserves native biology

recover

captured CTCs for culture or downstream analysis

analyze

CTCs using a wide range of downstream technologies including NGS, dPCR, qPCR, flow cytometry, FISH and more

or immunolabel

to enumerate CTCs or characterize surface proteins on-slide using fluorescent antibodies

Discover the flexibility

Try a Genesis System demo in your lab for your cell applications

flow →

capture →

recover →

analyze →

immunolabel →

discover

Did you know?

Cell samples do not require pre-processing with the Genesis System
Celselect technology’s slide capture process is highly efficient, with liquid biopsy blood samples showing a 99.9% elimination rate of RBCs, WBCs, and other components
Cells flow along microfluidic channels in Celselect Slides™ that connect to >140,800 individual microchambers for cell capture
Microfluidics size-based cell capture provides extremely gentle handling of cells that importantly retains their native biology for cell culture and downstream gene expression analysis
Cell capture, recovery and labeling processes can be automated on-slide, saving you time and streamlining your workflow
Free analysis software is available for cell labeling and enumeration applications

Process more blood, capture more CTCs
NEW! Celselect Slides™ 2.0

Discover our latest advancement for CTC capture:

Accepts up to 10 mL liquid biopsy samples
140,800 microchambers for CTC capture
Single piece design optimizes workflow
On-slide immunofluorescent staining with Celselect Slides validated antibodies
Recover captured CTCs for culture or downstream analysis

Learn More

Celselect Slides™ Validated Antibodies

A critical step for successful enumeration of captured CTCs and rare cells is antibody panel design

Image
Download our Quick Guide

Discover the key considerations for creating an optimized antibody panel for cell enumeration with CTCs and rare cells captured with Celselect Slides™. Our Quick Guide will lead you step-by-step through everything you need to know for design of your antibody panels, a part of the sample prep for our Enumeration Direct or Indirect Stain Kits.
Browse our Validated Antibodies

Browse our selection of Celselect Slides™ validated antibodies for creation of your staining panels.

Meet our 2023 Celselect Grant Recipients

In 2023 we created the Celselect Research Grant Program to support excellence in single- and rare cell research. After a rigorous selection process, we’re pleased to announce those scientists who were selected to receive a 2023 Celselect Research Grant. Exciting research begins for these 10 single-cell researchers who will use the Genesis Cell Isolation System and Celselect Slides™ to study topics from CTCs and cancer metastasis, to exercise-induced conditioning of PBMCs to promote vascular benefits. We'll be highlighting the work of all of this year's Grant recipients in the coming weeks, but you can learn more about their research right now here.

Learn More

Register For Our Latest Celselect Webinars

Gaining multi‑dimensional insights into cancer heterogeneity webinar

Gaining multi‑dimensional insights into cancer heterogeneity: Co‑analysis of CTCs and ctDNA derived from a single liquid biopsy sample

Date & Time: On-demand
Speakers: Yoon-Tae Kang, Ph.D., Staff Scientist, Marketing Applications, Digital Biology Group, Bio‑Rad Laboratories, and Abiodun Bodunrin, Ph.D., Application Scientist, Marketing Applications, Digital Biology Group, Bio‑Rad Laboratories

Visit Us At 2024 Scientific Conferences

Carolina and Jeanne, 2022 ISBL Conference

Carolina Reduzzi and Jeannine Donahue from Weill Cornell Medicine visit the Bio-Rad booth at the 2022 ISLB Conference in Miami, FL

Visit the Bio-Rad booth at the following 2024 scientific conferences to see a Genesis System and experience a virtual reality demo.

AACR — April 5-10, San Diego
CYTO — May 4-8, Edinburg, Scotland
ASHG — Nov 5-9, Denver
AACR Special Conference: Liquid Biopsy — Nov 13-16, San Diego
AMP — Nov 21-23, Vancouver, British Columbia, CA
ISLB — Nov 23-25, Denver
San Antonio Breast Cancer Symposium (SABCS) — Dec 10-14, San Antonio

Downloadable Resources

Celsect slides technology application note

Application Notes & Protocols

Celselect Slides™ Technology

Discover the advantages of Celselect Technology in CTC and ctDNA analyses.
Profiling EGFR DNA Mutation Analysis in Circulating Rare Cells using Celselect Slides™ and ddPCR.

Get our optimized workflow for cancer-specific mutation detection using ddPCR following rare cell capture and recovery from Celselect Slides™.
Dual isolation and profiling of CTCs and ctDNA using the Genesis System and ddPCR

Discover a workflow for co-isolation and analysis of CTCs and ctDNA from one liquid biopsy sample using the Genesis System with Celselect Slides™ and ddPCR.

Infographics

Immunotherapy Research Applications: CTC Analysis

Learn how CTC analysis contributes to discovery, research and development of new immunotherapies for cancer.

Publications

Celselect Slides™ Publication List

See Celselect Slides™ in action for translation oncology, diagnostics, and more.

Product Brochures

Genesis System Brochure

Check out the capabilities of the Genesis System and Celselect Slides Technology.

Product Information

Genesis System

Visit the Genesis System product page to view full system details.
Celselect Slides Enumeration Direct Stain Kit 2.0

For cell capture and staining via labeled-primary antibody.
Celselect Slides Enumeration Indirect Stain Kit 2.0

For cell capture and staining via labeled-secondary antibody.
Celselect Slides Enrichment Kit 2.0

For cell capture and recovery to be used in downstream applications (sequencing, dPCR, FISH, western blotting, etc).

Need Help with Cell Capture, Recovery, and Analysis? Chat with a Bio-Rad Cell Expert!

Selecting, capturing and recovering cells-of-interest from liquid biopsy, cell culture and environmental samples that retain their native biology can be problematic. Bio-Rad cell experts have the background and technology expertise to help you on your journey. Complete the information below to have an expert contact you! To report problems or issues, please contact Customer or Technical Support.

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