EconoFit CHT Column Screening Pack #17007881

EconoFit CHT Column Screening Pack


A collection of four prepacked ceramic apatite chromatography columns, 7 mm x 25 mm, for media screening experiments and small-scale method development with NGC Systems or any chromatography system



The EconoFit CHT Column Screening Pack is a collection of four ceramic apatite chromatography media columns, which can be screened to determine the optimal conditions for the purification of your biomolecules. These media offer unique selectivities and often separate biomolecules that other chromatography media are unable to differentiate. Please also view Bulletin 6530 which demonstrates the importance of resin/column screening for method development.

EconoFit CHT Column Screening Pack Components

The EconoFit CHT Column Screening Pack consists of the following columns:

Packed Media (1 ml) Catalog Number
CHT Type I, 40 µm 12009255
CHT Type II, 40 µm 12009259
CHT XT, 40 µm 12009261
CFT II, 40 µm 12009252


CHT Ceramic Hydroxyapatite Media

CHT Ceramic Hydroxyapatite Media is a spherical, macroporous form of hydroxyapatite. It has been sintered at high temperatures to modify it from a nanocrystalline to a ceramic form. Unlike most other chromatography adsorbents, CHT Media act as both the ligand and the support matrix. They offer unique selectivities and often separate biomolecules that appear homogeneous using other chromatographic methods.

Biomolecules can interact with CHT through calcium affinity interactions and/or cation exchange interactions. The diverse binding capabilities of CHT Media for host cell proteins, leached protein A, antibody dimers and aggregates, nucleic acids, and viruses allow its use at any purification stage from initial capture to final polishing.

CFT Ceramic Fluoroapatite Media

CFT Ceramic Fluoroapatite Media is a composite of fluoroapatite and hydroxyapatite prepared by chemically converting hydroxyapatite nanocrystals to fluoroapatite with a fluorine reagent. CFT Media can be used under stringent chromatography conditions to separate acidic proteins requiring buffered conditions as low as pH 5.6 with minimal effect on the solubility or lifetime of the support.

Related Products



Number Description Options
Instruction Manual, EconoFit CHT, CHT XT, MPC and CFT Columns
Mixed-Mode Chromatography: Ceramic Apatite Media Flier
Ceramic Hydroxyapatite Application Guide for Process Development and Scale-Up
[ Add to Cart (Free) ]
How Does CHT™ Ceramic Hydroxyapatite Media Work (Poster), Ver A
CHT™ Ceramic Hydroxyapatite XT Media Product Information Sheet
CFT Ceramic Fluoroapatite Product Information Sheet, Rev B
Practical Guide: Selecting the Optimal Resins for Mammalian Virus Process Purification and Clearance, Ver A
Mammalian Virus Purification Using Ceramic Hydroxyapatite, Rev A
[ Add to Cart (Free) ]
Practical Guide: Selecting the Optimal Resins for Endotoxin Depletion in Process Purification, Ver A
Removing the Aggregates of an Acidic Monoclonal Antibody with CHT Ceramic Hydroxyapatite XT Media Application Note
Protein Purification Workflow Development Using the Bio-Rad NGC Chromatography System and Stain-Free Gel Technology Application Note
[ Add to Cart (Free) ]
A Nuvia IMAC Resin–Based Purification Workflow for the Production of Highly Pure Recombinant Proteins
Monoclonal Antibody Purification Using UNOsphere SUPrA Media, Rev A
[ Add to Cart (Free) ]
Mixed-Mode Chromatography for mAb S Aggregate Removal: Comparison of CHT™ Ceramic Hydroxyapatite, Capto adhere, and Capto adhere ImpRes, Ver A
[ Add to Cart (Free) ]
Ceramic Apatite-Based Chromatography Media Publications List, Ver A