
Description
Description
CHT Ceramic Hydroxyapatite XT Media (CHT XT) is a calcium affinity cation exchange chromatography media. It is engineered with advanced technology, resulting in unique selectivity and robust, uniformly-sized beads with excellent pressure-flow properties. The chemical composition of CHT XT is (Ca10(PO4)6(OH)2) and it is a mixed-mode media. Biomolecules can interact with CHT through calcium affinity interactions and/or cation exchange interactions. It provides unparalleled separation properties and resolution. It can be used in applications such as purification of enzymes, monoclonal and polyclonal antibodies of various classes, antibody fragments, and bispecific antibodies; efficient isolation and purification of viruses and virus-like particles (VLPs); and separation of supercoiled DNA from linear duplexes as well as single stranded from double-stranded DNA. It is ideal for large scale bioprocess applications.
CHT XT Media delivers
- Unique selectivity
- Efficient single-step clearance of aggregates and other impurities
- High physical and chemical stability
- Straightforward column packing

Learn Best Practices and Guidelines for Packing CHT Media
These guidelines for handling and packing are recommended for all CHT users to ensure reproducible and high-quality results. Please download the CHT Application Guide for specific details on recommended buffers and slurry calculations.
Watch Videos | Download Application Guide
More Information
- CHT Ceramic Hydroxyapatite XT Product Information Sheet
- CHT Ceramic Hydroxyapatite XT Manual
Product Formats
Product | Catalog Number |
CHT XT Media, 10 g | 12002457 |
CHT XT Media, 100 g | 12002454 |
CHT XT Media, 1 kg | 12002456 |
CHT XT Media, 5 kg | 12002455 |
Specifications
Specifications
Ordering
Ordering
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Pkg of 1, 1 ml, prepacked mixed mode column, 7 mm x 25 mm, max. pressure 72 psi, for use with NGC Systems or any chromatography system








