High-Throughput Antibody Screening

Maximize Data Generation for Antibody Discovery
and Development

Turn your lab into a data generating powerhouse with an automation-ready flow cytometer designed to enable high-throughput antibody screening.

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When your mission is to generate data quickly and efficiently to support therapeutic antibody discovery and development teams, you need reliable tools that are easy to use, easy to maintain, and can deliver data with little hands-on time. But if you run a flow cytometry lab, you may wonder how more efficiency can be achieved, given the limitations of your existing instrumentation.

The answer is with an automation-ready flow cytometer that can enrich discovery with multi-parameter analysis — the ZE5 Cell Analyzer™ from Bio-Rad.

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    Did you know?

    Many of the first fluorescent reporters used in flow cytometry were isolated by Leonard “Len” A. Herzenberg, et al, from seaweeds found in the ocean just off the coast of California, close to Stanford University.1

Put Flow Cytometry into Your Automated Workflows with the ZE5 Cell Analyzer

Designed to enable high-throughput antibody screening, the ZE5 Cell Analyzer is a flow cytometer that takes efficient data generation to a whole new level.

The ZE5 Cell Analyzer is automation-ready, delivering data faster and with less hands-on time:

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    Runs unattended 24/7 when integrated with external fluidics and robotic automation

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    Analyzes one 96-well plate every 15 minutes and one 384-well plate every 50 minutes

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    Seamlessly switches between tube racks and multiple plate formats without needing to change any hardware thanks to the integrated sample loader

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    Integrates with laboratory robotics system via a device-agnostic application programming interface (API)

Learn more about high-throughput screening and how it has revolutionized the potential for increasing the scope of experiments »

Capture Richer Data Sets with the ZE5 Cell Analyzer

The advanced capabilities of the ZE5 Cell Analyzer ensure that every data set you generate delivers maximum value with every sample.

  • Capture rare events

    With the ability to acquire up to 100,000 events/second with no loss of data, you increase the likelihood of capturing rare events.

  • Efficiently build high-dimensional data sets

    Deliver highly nuanced insights to discovery and development teams by running multi-parameter studies with up to 27 colors.

Using the ZE5 Cell Analyzer for High-Throughput Antibody Screening

Resources

Publications

Cross-Neutralization of SARS-CoV-2 by a Human Monoclonal SARS-CoV-2 Antibody
Read how the ZE5 Cell Analyzer allowed rapid selection of SARS-CoV-2 neutralizing antibodies.

Utilizing the Multi-Parameter Capability of the ZE5 to Monitor T-Cell Exhaustion Following Immunotherapy
Learn advancements in flow cytometry that take it from a technique to a powerful tool that goes beyond instrumentation.

Documents

References

  1. Herzenberg LA, Parks D, Sahaf B, Perez O, Roederer M, Herzenberg LA. The history and future of the fluorescence activated cell sorter and flow cytometry: a view from Stanford. Clin Chem. 2002;48(10):1819-1827.

Ready to learn how Bio-Rad can streamline your high-throughput antibody screening? Our scientists are here to help.

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