High-Throughput
Antibody Screening
Maximize Data Generation for Antibody Discovery
and Development
Turn your lab into a data generating powerhouse with an automation-ready flow cytometer designed to enable high-throughput antibody screening.
Start a Conversation with a SpecialistWhen your mission is to generate data quickly and efficiently to support therapeutic antibody discovery and development teams, you need reliable tools that are easy to use, easy to maintain, and can deliver data with little hands-on time. But if you run a flow cytometry lab, you may wonder how more efficiency can be achieved, given the limitations of your existing instrumentation.
The answer is with an automation-ready flow cytometer that can enrich discovery with multi-parameter analysis — the ZE5 Cell Analyzer™ from Bio-Rad.
-
Did you know?
Many of the first fluorescent reporters used in flow cytometry were isolated by Leonard “Len” A. Herzenberg, et al, from seaweeds found in the ocean just off the coast of California, close to Stanford University.1
Put Flow Cytometry into Your Automated Workflows with the ZE5 Cell Analyzer
Designed to enable high-throughput antibody screening, the ZE5 Cell Analyzer is a flow cytometer that takes efficient data generation to a whole new level.
The ZE5 Cell Analyzer is automation-ready, delivering data faster and with less hands-on time:
Runs unattended 24/7 when integrated with external fluidics and robotic automation
Analyzes one 96-well plate every 15 minutes and one 384-well plate every 50 minutes
Seamlessly switches between tube racks and multiple plate formats without needing to change any hardware thanks to the integrated sample loader
Integrates with laboratory robotics system via a device-agnostic application programming interface (API)
Capture Richer Data Sets with the ZE5 Cell Analyzer
The advanced capabilities of the ZE5 Cell Analyzer ensure that every data set you generate delivers maximum value with every sample.
-
Capture rare events
With the ability to acquire up to 100,000 events/second with no loss of data, you increase the likelihood of capturing rare events.
-
Efficiently build high-dimensional data sets
Deliver highly nuanced insights to discovery and development teams by running multi-parameter studies with up to 27 colors.
Using the ZE5 Cell Analyzer for High-Throughput Antibody Screening
-
Custom Antibody Screening and Characterization
See how our own custom antibody generation service teams use flow cytometry for antibody screening and characterization.
Resources
Publications
Cross-Neutralization of SARS-CoV-2 by a Human Monoclonal SARS-CoV-2 Antibody
Read how the ZE5 Cell Analyzer allowed rapid selection of SARS-CoV-2 neutralizing antibodies.
Utilizing the Multi-Parameter Capability of the ZE5 to Monitor T-Cell Exhaustion Following Immunotherapy
Learn advancements in flow cytometry that take it from a technique to a powerful tool that goes beyond instrumentation.
Documents
Why Flow Cytometry is Ideal for Lead Candidate Screening
Learn how flow cytometry played a crucial role in the discovery and development of novel therapies for SARS-CoV-2 from research papers published.
Using Flow Cytometry to Advance Therapeutic Antibody Development
Rapid, accurate lead candidate identification is easy with the right tools. We describe the benefits of using flow cytometry to perform cell-based assays.
Maximizing Screening Speed and Throughput with Flow Cytometry
This infographic highlights challenges for high-throughput flow cytometry and how the ZE5 Cell Analyzer has solutions to overcome them.
Elucidating Complex Flow Cytometry Studies with the Speed and Sensitivity of the ZE5 Cell Analyzer
See the multi-parameter capability of the ZE5 Cell Analyzer in this poster presentation.
References
- Herzenberg LA, Parks D, Sahaf B, Perez O, Roederer M, Herzenberg LA. The history and future of the fluorescence activated cell sorter and flow cytometry: a view from Stanford. Clin Chem. 2002;48(10):1819-1827.
Ready to learn how Bio-Rad can streamline your high-throughput antibody screening? Our scientists are here to help.
Start a Conversation with a SpecialistDiscover More Therapeutic Antibody Development Solutions
Therapeutic Antibody
Development OverviewMove faster and make more informed decisions with products, services, and expert scientific support from antibody discovery to IND.
Cell Line Development
Streamline cell line characterization using less sample with ddPCR technology.
Custom Antibody Generation
Develop assays faster with the quick turnaround times and flexibility of antibody phage display combined with SpyTag technology.
Antibody Purification
Find resins for challenging purifications using the help of our expert purification scientists.