Chelex 100 Molecular Biology Grade Resin can be used for fast, easy DNA purification from many sample types including forensic, blood, mammalian cells, and bacteria. DNA extracted using Chelex 100 Resin is suitable for PCR.
Chelex 100 Resin chelates polyvalent metal ions, with a selectivity for divalent over monovalent ions of approximately 5,000 to 1. The resin avidly binds divalent cations such as Mg2+, inactivating DNases and other enzymes, as well as binding other compounds that can interfere with enzyme-based applications such as PCR and ligation. Due to the high selectivity for divalent over monovalent ions, Chelex 100 Molecular Biology Grade Resin can be used for DNA purification from samples with high levels of salts.