Chelex 100 Chelating Resin, molecular biology grade, 200–400 mesh, sodium form, 50 g #1421253



50 g, molecular biology grade cation exchange resin, sodium form, 1% cross-linkage, 200–400 dry mesh size, 75–150 µm wet bead size, ~3,500 MW limit, can be used for chromatography or molecular biology applications

Safety Data Sheet

Safety Data Sheet



Chelex 100 and COVID-19

Chelex 100 Resin in Pathogen Detection

Streamline your viral RNA preparation with Chelex 100 Resin or InstaGene Matrix.

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Choose molecular biology grade Chelex 100, a weak cation exchange resin, for DNA or RNA preparation for downstream detection by methods such as PCR, RT-qPCR, RT-ddPCR or LAMP.

  • High degree of selectivity for divalent over monovalent ions (ca. 5,000 to 1)
  • Strong attraction for transition metals, even in highly concentrated salt solutions
  • Limits activity of enzymes, including metallo-nucleases, that require divalent cations for activity
  • Enables fast, easy and cost-effective method for nucleic acid preparations from many sample types including cell cultures, blood or tissues
  • Long history of being utilized for molecular biology applications. Please view Bulletin 3356 for a list of publications
  • Certified to be free of endo- and exonucleases, and ligase inhibitors
  • Larger volumes and special packaging are available upon request
Chelex 100 Resin Sample Preparation Workflow

Chelex 100-based sample preparation workflow overview.

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