Bio-Plex Pro™ RBM Apoptosis Panel 2 #171WAR2CK

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Overview

1 x 96-well, includes magnetic capture beads, detection antibodies, standards, controls, standard diluent, buffers, streptavidin-PE, flat bottom plate, plate seals, for the detection of 5 apoptosis markers in cell and tissue lysates
Safety Data Sheet

Safety Data Sheet

Description

Description

Use the Bio-Plex Pro RBM apoptosis panel 2 multiplex assay for detecting the intracellular proteins involved in the commitment, onset, and induction of apoptosis by the intrinsic pathway listed below:

  • Bad
  • Bax/Bcl-2 dimer
  • Bcl-xL
  • Bim
  • Mcl-1

    For use with the following sample types:

    • Cell lysates
    • Tissue lysates

    Benefits

    • Optimized for high precision and lot-to-lot reproducibility of sample measurements
    • Magnetic beads for simplified plate processing
    • 2-level quality controls with kit lot-specific ranges
    • Assay quick guide to get you started right away

    Kit Components

    • 6.5 µm magnetic capture beads
    • Detection antibodies
    • Standards
    • 2-level controls
    • Standard diluent
    • Blocking buffer
    • Lysate dilution buffer (LDB)
    • Cytosolic extraction buffer (CEB)
    • 10x assay buffer
    • 10x streptavidin-PE
    • Flat bottom plate
    • Plate seals
    • Instructions

    Other Available Apoptosis Assays

    Run all three Bio-Plex Pro RBM apoptosis panels for a more complete picture of the intrinsic pathway:

    • Panel 1 (171-WAR1CK) detects Bak, Bax, Lamin B, and Smac
    • Panel 2 (171-WAR2CK) detects Bad, Bax/Bcl-2 dimer, Bcl-xL, Bim, and Mcl-1
    • Panel 3 (171-WAR3CK) detects active caspase-3, Bcl-xL/Bak dimer, Mcl-1/Bak dimer, and survivin

    Instrument Compatibility

    Compatible with these readers and wash stations:

    More Information

    To learn more about performance characteristics and other cancer-related panels, refer to the documents listed below: