Bio-Plex Multiplex SARS-CoV-2 Serology Assay Kits and Reagents

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Overview

Provides sensitive and specific measurements of antibodies against four SARS-CoV-2 proteins: nucleocapsid, receptor binding domain, spike 1, and spike 2 viral antigens.

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Description

Description

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Bio-Plex Pro SARS-CoV-2 Serological Assays provide sensitive and specific measurements of antibodies against four SARS-CoV-2 proteins: nucleocapsid, receptor binding domain, spike 1, and spike 2 viral antigens. Three isotype-specific antibodies are detected: IgA, IgG, and IgM, providing the spectrum of antibody response over time after COVID-19 vaccine administration or natural exposure to SARS-CoV-2.

Bio-Plex Pro SARS-CoV-2 Serology Assays are for research use only.

Ordering Options for Bio-Plex Serology Assays

Select complete kits for multiplex target panels.

  • Detect individual anti-SARS-CoV-2 antibodies, or combine components to create multiplex assays

How to Order Individual Bio-Plex SARS-CoV-2 Serology Assay Components

Human samples require four components for a complete assay:

  • Antigen-coupled beads
  • Isotype-specific detection antibody
  • Isotype-specific control set
  • Human Serology Assay Reagent Kit (12014777)

For samples from other species, researchers must provide their own biotinylated anti-species detection antibody, positive and negative controls, and select a reagent kit appropriate for the chosen species.

  • Bio-Plex Pro Reagent Kit V (12002798) — for mouse and rat
  • Bio-Plex Pro Reagent Kit III (171304090M) — for other species

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items

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12014665

1 x 96-well, includes magnetic capture beads coupled with SARS-CoV-2 nucleocapsid, receptor-binding domain, spike 1, and spike 2 viral antigens, anti-human IgA detection antibody, ready-to-use positive control, ready-to-use negative control, wash buffer, assay buffer, serology sample diluent, detection antibody diluent, streptavidin-PE, 96-well flat-bottom plate, and sealing tape.

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12014634

1 x 96-well, includes magnetic capture beads coupled with SARS-CoV-2 nucleocapsid, receptor-binding domain, spike 1, and spike 2 viral proteins, anti-human IgG detection antibody, ready-to-use positive control, ready-to-use negative control, wash buffer, assay buffer, serology sample diluent, detection antibody diluent, streptavidin-PE, 96-well flat-bottom plate, and sealing tape.

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12014666

1 x 96-well, includes magnetic capture beads coupled with SARS-CoV-2 nucleocapsid, receptor-binding domain, spike 1, and spike 2 viral antigens, anti-human IgM detection antibody, ready-to-use positive control, ready-to-use negative control, wash buffer, assay buffer, serology sample diluent, detection antibody diluent, streptavidin-PE, 96-well flat-bottom plate, and sealing tape.

Kits & Reagents

Kits & Reagents

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12014777
1 x 96 well, assay buffer, wash buffer, serology sample diluent, detection antibody diluent, streptavidin-PE, flat-bottom plate, and sealing tape.
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12002798
1 x 96-well, includes mouse HP detection antibody diluent, standard diluent, sample diluent, assay buffer, wash buffer, streptavidin-PE, flat bottom plate, and sealing tape for use with magnetic separation methods
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Bio-Plex SARS-CoV-2 Controls
12014775

Set of 2, negative control and positive control containing IgA antibodies against four SARS-CoV-2 viral antigens, for use with Human IgA SARS-CoV-2 Serology Assays and Reagent Kit (12014777), for 96 reactions.

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12014774

Set of 2, negative control and positive control containing IgG antibodies against four SARS-CoV-2 viral antigens, for use with Human IgG SARS-CoV-2 Serology Assays and Reagent Kit (12014777), for 96 reactions.

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Bio-Plex SARS-CoV-2 Controls
12014776

Set of 2, negative control and positive control containing IgM antibodies against four SARS-CoV-2 viral antigens, for use with Human IgM SARS-CoV-2 Serology Assays and Reagent Kit (12014777), sufficient for 96 reactions.

Antigens

Antigens

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12014667

Pkg of 1, 4-plex coupled magnetic beads coated with SARS-CoV-2 nucleocapsid (N), receptor-binding domain (RBD), spike 1 (S1), and spike 2 (S2) viral proteins, sufficient for 96 reactions; Requires isotype-specific detection antibody, reagent kit, and isotype-specific control set.

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12014773
Pkg of 1, SARS-CoV-2 N viral protein coupled magnetic beads, for capturing anti-SARS-CoV-2 antibodies specific for nucleocapsid from multispecies serum or plasma, sufficient for 96 reactions; Requires isotype-specific detection antibody, reagent kit, and isotype-specific control set.
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12015406

Pkg of 1, SARS-CoV-2 RBD viral protein coupled magnetic beads, for capturing anti-SARS-CoV-2 antibodies specific for RBD from multispecies serum or plasma, sufficient for 96 reactions; Requires isotype-specific detection antibody, reagent kit, and isotype-specific control set.

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12014771

Pkg of 1, SARS-CoV-2 S1 viral protein coupled magnetic beads, for capturing anti-SARS-CoV-2 antibodies specific for Spike 1 from multispecies serum or plasma, sufficient for 96 reactions; Requires isotype-specific detection antibody, reagent kit, and isotype-specific control set.

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12014772
Pkg of 1, SARS-CoV-2 S2 viral protein coupled magnetic beads, for capturing anti-SARS-CoV-2 antibodies specific for Spike 2 from multispecies serum or plasma, sufficient for 96 reactions.

Antibodies

Antibodies

Documents

Documents

Number Description Options
7417
Bio-Plex Pro SARS-CoV-2 Multiplex Serology Assays Flier
7430
Bio-Plex Pro Human SARS-CoV-2 N/RBD/S1/S2 4-Plex Panel Product Information Sheet
10000133853
Bio-Plex Pro Human SARS-CoV-2 Serology Assays Instruction Manual
3303
Bio-Plex Pro Human IgA, IgG, and IgM SARS-CoV-2 Serology Assay Performance in Freeze-Thawed and Refrigerated Serum, Plasma, and Saliva Samples
3299
Calibration Factors Using WHO International Standard (NIBSC 20/136) for Anti–SARS-CoV-2 Immunoglobulins Flier
10000133854
Bio-Plex Pro SARS-CoV-2 Serology Assay Quick Guide
7459
Bio-Plex Pro Human IgG SARS-CoV-2 Semi-Quantitative Assay Protocol
3224
Bio-Plex Pro Human IgA and IgM SARS-CoV-2 Serology Assays Protocol
3208
Quantitative Bio-Plex Pro Human IgG, IgA, and IgM SARS-CoV-2 Serology Assays Using a Standard Curve Application Note
3235
Comparison of Bio-Plex Pro Assay Performance Using the Bio-Plex 200 and Luminex xMAP INTELLIFLEX Systems