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Description
Description
Questions? Ask a Bio-Plex Specialist.
The Bio-Plex Pro Human IgG SARS-CoV-2 S1/S2/N/RBD 4-Plex Panel detects IgG antibodies against SARS-CoV-2 nucleocapsid, receptor-binding domain, spike 1, and spike 2 viral proteins. Measuring antibodies against each SARS-CoV-2 viral protein enables researchers to study the immune response to natural infection, vaccination, and levels of exposure in populations.
Features and Benefits
- Comprehensive panel coverage — detects antibody response to four highly relevant SARS-CoV-2 viral proteins in a single well
- High specificity and sensitivity — builds greater confidence in a positive or negative assessment in samples for seroprevalence studies
- Fast protocol — results in less than 3 hours
- Reproducibility — attain consistent results in your experiments with a robust, magnetic bead-based workflow
- Streamlined data analysis — manage and analyze your data with ease using Bio-Plex Manager and Bio-Plex Data Pro Software
Kit Components
- Magnetic capture beads coupled with SARS-CoV-2 viral proteins:
- Nucleocapsid protein
- Receptor-binding domain (RBD) protein
- Spike 1 protein
- Spike 2 protein
- Anti-human IgG detection antibody
- Ready-to-use positive and negative controls
- Wash buffer and assay buffer
- Sample and detection antibody diluents
- Streptavidin-PE
- 96-well flat-bottom plate and sealing tape
Individual kit components can also be purchased to create custom assays.
Instrument Compatibility
Compatible with all xMAP Platforms:
Specifications
Specifications
Reactive species
Human
Intra-assay precision, %CV
<10%
Inter-assay precision, %CV
<15%
Clinical specificity
(n = 282 negative samples)N = 99%, RBD = 96%, S1 = 99%, and S2 = 95%
Clinical sensitivity
(n=65 SARS-CoV-2 positive samples)N = 100%, RBD = 100%, S1 = 98%, and S2 = 100%
Compatible sample matrices
Serum, plasma
Documents
Documents
Number Description Options
10000133853
Bio-Plex Pro Human SARS-CoV-2 Serology Assays Instruction Manual
10000133854
Bio-Plex Pro SARS-CoV-2 Serology Assay Quick Guide
3208
Quantitative Bio-Plex Pro Human IgG, IgA, and IgM SARS-CoV-2 Serology Assays Using a Standard Curve Application Note
3303
Bio-Plex Pro Human IgA, IgG, and IgM SARS-CoV-2 Serology Assay Performance in Freeze-Thawed and Refrigerated Serum, Plasma, and Saliva Samples
3299
Calibration Factors Using WHO International Standard (NIBSC 20/136) for Anti–SARS-CoV-2 Immunoglobulins Flier
7459
Bio-Plex Pro Human IgG SARS-CoV-2 Quantitative Assay Protocol
3224
Bio-Plex Pro Human IgA and IgM SARS-CoV-2 Serology Assays Protocol