The Gold Standard in
For Diabetes Testing, Hemoglobinopathy Testing,
and Quality Control
The VARIANT II TURBO System is a fully automated, robust HPLC system for medium to high volume laboratories that identifies HbA1c without common hemoglobin variant interferences.*Contact a Specialist
Release your HbA1c Results Faster
Watch how the VARIANT II TURBO System simplifies A1c operations and eliminates redundant, low value tasks to release 2,500 HbA1c results faster than other non-Bio-Rad HPLC systems.Download Case Study
Every Patient Deserves
Confidently report HbA1c results with
the VARIANT II TURBO System
- Aids in the diagnosis of patients with diabetes
- Identifies those at risk of developing diabetes
- Monitors the progress of those living with diabetes
Not all HbA1c Assays are Equal
Effects of Different Rare Hb Variants on HbA1c Measurement in Eight Methods
Randie R. Little et al. (2015) Journal of Diabetes and Science and Technology1
The study examined analytical interference from 49 different less common variants comparing seven different HbA1c methods. HbA1c accuracy was assessed as well as the likelihood for the systems to report inaccurate results. The authors noted that previous studies with some assay methods have shown interference with HbA1c measurement from the four most common heterozygous Hb variants (HbAS, HbAE, HbAC, and HbAD).
Bio-Rad HPLC systems outperformed other HbA1c testing systems. The VARIANT II TURBO System reported 97.7% accurate results in the presence of hemoglobin variants. The table below illustrates the clinical benefit of Bio-Rad ion-exchange HPLC for patient diagnosis and treatment.
The authors concluded that in order to ensure accurate HbA1c results, it’s important to know if patients have a hemoglobin variant and if so, how that variant affects their HbA1c results. Laboratories should take care when reporting results if a variant is suspected.
Bio-Rad HPLC Reveals HbF for a Diagnosis You Can Trust
Are You Reporting Valid HbA1c Results?
HbA1c testing methods that don't see common hemoglobin variants or elevated levels of hemoglobin F might lead to misdiagnosis and unnecessary or delayed patient treatment.
Case Study Results:**
- Bio-Rad VARIANT II TURBO System reveals the presence of HbF so you can confidently report HbA1c results to your clinicians.
- Immunoassays do not reveal the presence of HbF. So you might not know the result was invalid and unknowingly report incorrect results.
For Quality Patient Care
The VARIANT II TURBO System brings speed, efficiency and accuracy to laboratories demanding a robust system for processing thousands of tests a month.
Save Time and Labor
The fully-automated VARIANT II TURBO System requires minimal maintenance and no sample preparation.
For Demanding HbA1c Workloads
Report HbA1c results every 97 seconds with the Clinical Data Management (CDM) software.
For Better Patient Care
Ion-exchange HPLC technology is the method of choice for clinicians seeking accurate results without common hemoglobin variant interference.*
Watch the video to learn more about the Easy Release Cartridge Holder.
The VARIANT II TURBO Easy Release Cartridge Holder simplifies changing cartridges and prefilters.Download Brochure
For Use in Diagnosing Diabetes
Be confident in reporting high quality, clinically-relevant HbA1c results to aid physicians in diagnosing those who have diabetes, identifying people at risk for developing the disease, or monitoring the progress of those living with diabetes.
VARIANT II TURBO HbA1c Kit - 2.0***
HbA1c results reportable with no interference in the presence of:
- The most common heterozygous hemoglobin variants: HbAS, HbAC, HbAD, and HbAE
- HbF ≤ 25%
- Carbamylated hemoglobin (CHb)
- Labile A1c (LA1c)
- Acetylated hemoglobins
- Lipemia ≤ 6,000mg/dL (60g/L)
Confidence in Your Results
NGSP certified, IFCC anchored and CE-marked
Flexible and Efficient
- Streamline inventory management: Interchangeable kit components with long shelf lives
- Reduce hands-on time: One calibration per cartridge (2,500 tests) and on-board QC management
- Maximize workflow: Fully automated walk-away operation with minimal maintenance
Automate with VARIANT II TURBO Link
Improve your laboratory's workflow with the VARIANT II TURBO Link Hemoglobin Testing System, designed to integrate the VARIANT II TURBO System with the SysmexTM XN-9000 Automated Hematology System.
The fully-automated system combines Bio-Rad's leadership in HbA1c testing with Sysmex's expertise in automation to help you be the difference for your clinicians with timely, accurate results.Download Brochure
Integration with the SysmexTM XN-9000 Automated Hematology System provides on-demand HbA1c testing results 24/7.
Sysmex Lavender Top ManagementTM solution and SysmexTM WAM logic rule database provide an efficient and LEAN workflow.
Backed by Bio-Rad's world-class service and customer support.