Access high-performance genome-wide chromatin profiling with SureCell
Explore the Epigenomic Landscape of Single Cells with the ATAC you seq
Gain access to high-performance chromatin profiling to unravel the complexities of cellular heterogeneity, differentiation, and disease-specific alterations in gene regulation. With ATAC-seq (Assay for Transposase-Accessible Chromatin using sequencing), you can delve into the regulatory landscape of individual cells, unlocking invaluable insights into the epigenomic mechanisms that shape their behavior.
Bio-Rad's Surecell ATAC-seq Library Prep Kit, coupled with the ddSEQ™ Single Cell Isolator, provides a simple and cost-efficient solution, making single-cell ATAC-seq more accessible than ever before. Generate high-resolution genome-wide data and achieve sensitive profiling of chromatin accessibility.
Watch the video to learn more on the power and potential of single-cell ATAC-seq.
Discover simple, highly efficient droplet-based single-cell ATAC-seq
Experience the streamlined workflow, driven by our trusted digital droplet technology of ddSEQ Single-Cell Isolator and SureCell ATAC-seq Library Prep Kits.
or Single Cells
Imagine incorporating robust whole genome open chromatin interrogation into your current cell and translational studies. Get the efficiency, sample flexibility, scalability, and sensitivity of larger systems, but with affordability to do more with your budget.
What can you expect from ddSEQ and SureCell ATAC-seq?
Check out these features:
- High cell capture efficiency (60-80%)
- Flexible sample input: isolated nuclei or whole cells
- Output scalability (400-5,000 single-cell ATAC-seq libraries per sample)
- Fast; 5-minute partitioning and barcoding
- Exceptional sensitivity (TSS Enrichment Scores>30, FRiP>30%)
- Includes streamlined and robust Omnition Bioinformatics Analysis Software
Explore the Key Applications of Single-Cell ATAC-seq
Cell type identification and heterogeneityAnalyze chromatin accessibility profiles to determine distinct cell types, explore cellular heterogeneity, and identify rare cell populations.
Gene regulation and enhancer activityInvestigate the regulatory landscape of individual cells, identify active enhancer regions, and unravel interactions between chromatin and gene-regulatory elements to understand gene expression regulation.
Cellular differentiation and developmentStudy how cells differentiate into different cell types, uncover epigenetic mechanisms driving cellular differentiation, and gain insights into cell fate determination.
Disease mechanisms and pathologyExplore disease-specific alterations in chromatin accessibility, identify regulatory elements associated with diseases, and understand the underlying epigenetic mechanisms contributing to disease progression.
Integration with other -omics dataCombine single-cell ATAC-seq with other techniques, such as single-cell RNA sequencing (scRNA-seq), for multi-omic analyses, enabling a deeper understanding of gene regulation in cellular processes and disease.
Attend Our Latest Single-Cell ATAC-seq Events
ImageASHG 2023, CoLab Presentation
Studying tumor heterogeneity using single cell ATAC-seq
Speaker: Fatima Valdes-Mora, PhD, Team Leader, Cancer Epigenetic Biology and Therapeutics, Children's Cancer Institute, UNSW Australia and Xiaoti Guo, Sr Product Manager, Single Cell Technologies, Bio-Rad Technologies
Date & Time: Thursday, November 2, 2023 from 1:05-1:35 pm EST
Deciphering Cancer Cell Heterogeneity for Precision Medicine
Speakers: Fatima Valdes-Mora, PhD, Team Leader, Cancer Epigenetic Biology and Therapeutics, Children's Cancer Institute, UNSW Australia
Date & Time: On-Demand 24/7
Browse Our Resources for Single-Cell ATAC-seq