ANA and ENA Screening Assays

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ANA and ENA Screening Assays

Overview

ANA and ENA Screening Assays

Bio-Rad Systemic Autoimmune Testing Products


Key Legends

The algorithm presented here illustrate Bio-Rad’s comprehensive product offering for all clinically relevant markers. They are not meant for clinical diagnostic purposes. Product list is not exhaustive.

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Bio-Rad offers a complete menu of CE-marked and FDA-cleared EIA assays. All assays feature common protocols, common reagents, color-coded breakaway wells and easy automation, allowing for simple, objective and sensitive autoimmune diagnostics.

Bio-Rad Autoimmune EIA Assay Characteristics

  • Sample dilution: 1:40 (only Anti-dsDNA and Anti-ssDNA are 1:100)
  • Sample volume: 10 µL
  • Incubation time: 90 minutes (30/30/30)
  • Incubation temperature: Room temperature (20–25°C)
  • Conjugate: HRP
  • Substrate: TMB

All of the Bio-Rad ANA and ENA Screening assays can be used to screen out patients negative for the antinuclear antibodies associated with various systemic rheumatic diseases such as systemic lupus erythematosus (SLE), mixed connective tissue disease (MCTD), Sjögren's syndrome (SS), progressive system sclerosis, scleroderma, polymyosistis/dermatomysitis and Raynaud’s phenomenon. The assays can also be used in conjunction with Bio-Rad’s individual antibody assays to identify specific autoantibodies. Rely on Bio-Rad’s comprehensive menu of ANA and ENA assays to identify and characterize individual or multiple autoantibodies associated with autoimmune diseases.

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Bio-Rad ANA Screening Test

96AN
Enzyme immunoassay to screen for panel of antinuclear antibodies (ANAs) associated with systemic rheumatic diseases (96 tests)

0 96AN /templatedata/internet/product_SKU/data/CDG/Autoimmune/Systemic-Autoimmune-Testing--N/96AN_0921120819081.xml 96AN <?xml version="1.0" encoding="UTF-8"?> <Deployments> <Node Name="QA"> <Deployment Id="StandardMetadata.jc99dtr0jc99dtr1" Class="com.interwoven.livesite.lscs.model.LSCSDeploymentImpl" Instance="jc99dtr0jc99dtr1"> <Name>StandardMetadata</Name> <TargetEnviroment>QA</TargetEnviroment> <LastExecutionTime Class="java.util.Date" Month="1" DayOfMonth="12" DayOfWeek="5" Year="2018" Hour="1" Minute="40" Second="24" ZoneOffsetMillis="0" Time="1515721224134">Fri Jan 12 01:40:24 UTC 2018</LastExecutionTime> </Deployment> <Vpath>/default/main/bio-rad/WORKAREA/default/templatedata/internet/product_SKU/data/CDG/Autoimmune/Systemic-Autoimmune-Testing--N/96AN_0921120819081.xml</Vpath> <LastExecutionTime Class="java.util.Date" Month="1" DayOfMonth="12" DayOfWeek="5" Year="2018" Hour="1" Minute="40" Second="24" ZoneOffsetMillis="0" Time="1515721224134">Fri Jan 12 01:40:24 UTC 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AE,AI,AL,AM,AR,AT,AU,AZ,BA,BD,BE,BF,BG,BH,BN,BO,BR,BW,CA,CH,CL,CM,CN,CO,CR,CY,CZ,DE,DK,DO,DZ,EC,EE,EG,EH,ER,ES,ET,FI,FM,FO,FR,GA,GE,GF,GH,GP,GR,GT,GU,HK,HN,HR,HT,HU,ID,IE,IL,IN,IS,IT,JM,JO,JP,KE,KH,KR,KW,KZ,LB,LI,LK,LT,LU,LV,MA,MD,MG,MK,ML,MO,MQ,MS,MT,MU,MX,MY,NG,NI,NL,NO,NP,NZ,OM,PA,PE,PF,PG,PH,PK,PL,PR,PS,PT,PW,PY,QA,RO,RS,RU,SA,SB,SE,SG,SI,SK,SN,ST,SV,TG,TH,TN,TO,TR,TT,TW,TZ,UA,UG,UK,US,UY,UZ,VA,VE,VU,XK,YE,ZA 2017-11-14 07:06:20 96an-bio-rad-ana-screening-test 96AN Bio-Rad ANA Screening Test Bio-Rad ANA Screening Test Enzyme immunoassay to screen for panel of antinuclear antibodies (ANAs) associated with systemic rheumatic diseases (96 tests) Enzyme immunoassay to screen for panel of antinuclear antibodies (ANAs) involved in systemic rheumatic diseases (96 tests) Enzyme immunoassay to screen for panel of antinuclear antibodies (ANAs) associated with systemic rheumatic diseases (96 tests) /webroot/web/images/cdg/products/autoimmune/sku_thumb/global/aibu_96an_tn.jpg /webroot/web/images/cdg/products/autoimmune/sku_view/global/aibu_96an_view.jpg /webroot/web/images/cdg/products/autoimmune/sku_feature/global/aibu_96an_feature.jpg preview RepEx 96AN Enzyme immunoassay to screen for panel of antinuclear antibodies (ANAs) involved in systemic rheumatic diseases (96 tests) 09/21/09 12:08 PM 09/21/19 12:08 PM AE,AI,AL,AM,AR,AT,AU,AZ,BA,BD,BE,BF,BG,BH,BN,BO,BR,BW,CA,CH,CL,CM,CN,CO,CR,CY,CZ,DE,DK,DO,DZ,EC,EE,EG,EH,ER,ES,ET,FI,FM,FO,FR,GA,GE,GF,GH,GP,GR,GT,GU,HK,HN,HR,HT,HU,ID,IE,IL,IN,IS,IT,JM,JO,JP,KE,KH,KR,KW,KZ,LB,LI,LK,LT,LU,LV,MA,MD,MG,MK,ML,MO,MQ,MS,MT,MU,MX,MY,NG,NI,NL,NO,NP,NZ,OM,PA,PE,PF,PG,PH,PK,PL,PR,PS,PT,PW,PY,QA,RO,RS,RU,SA,SB,SE,SG,SI,SK,SN,ST,SV,TG,TH,TN,TO,TR,TT,TW,TZ,UA,UG,UK,US,UY,UZ,VA,VE,VU,XK,YE,ZA en CDG /CDG/Autoimmune/Systemic-Autoimmune-Testing--N N 0 false false false /prd/en/US/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=96AN&CartQuote=QT&quantity= false true false null false null /prd/en/US/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=96AN&AddToDefaultWishList=true&quantity= false false true true false true false true /prd/en/US/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=96AN&quantity= 96AN
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Bio-Rad ANA Screening Test

576AN
Enzyme immunoassay to screen for panel of antinuclear antibodies (ANAs) associated with systemic rheumatic diseases (576 tests)

1 576AN /templatedata/internet/product_SKU/data/CDG/Autoimmune/Systemic-Autoimmune-Testing--N/576AN_0921120819175.xml 576AN <?xml version="1.0" encoding="UTF-8"?> <Deployments> <Node Name="QA"> <Deployment Id="StandardMetadata.jc99dtr0jc99dtr1" Class="com.interwoven.livesite.lscs.model.LSCSDeploymentImpl" Instance="jc99dtr0jc99dtr1"> <Name>StandardMetadata</Name> <TargetEnviroment>QA</TargetEnviroment> <LastExecutionTime Class="java.util.Date" Month="1" DayOfMonth="12" DayOfWeek="5" Year="2018" Hour="1" Minute="40" Second="24" ZoneOffsetMillis="0" Time="1515721224134">Fri Jan 12 01:40:24 UTC 2018</LastExecutionTime> </Deployment> <Vpath>/default/main/bio-rad/WORKAREA/default/templatedata/internet/product_SKU/data/CDG/Autoimmune/Systemic-Autoimmune-Testing--N/576AN_0921120819175.xml</Vpath> <LastExecutionTime Class="java.util.Date" Month="1" DayOfMonth="12" DayOfWeek="5" Year="2018" Hour="1" Minute="40" Second="24" ZoneOffsetMillis="0" Time="1515721224134">Fri Jan 12 01:40:24 UTC 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AE,AI,AL,AM,AR,AT,AU,AZ,BA,BD,BE,BF,BG,BH,BN,BO,BR,BW,CA,CH,CL,CM,CN,CO,CR,CY,CZ,DE,DK,DO,DZ,EC,EE,EG,EH,ER,ES,ET,FI,FM,FO,FR,GA,GE,GF,GH,GP,GR,GT,GU,HK,HN,HR,HT,HU,ID,IE,IL,IN,IS,IT,JM,JO,JP,KE,KH,KR,KW,KZ,LB,LI,LK,LT,LU,LV,MA,MD,MG,MK,ML,MO,MQ,MS,MT,MU,MX,MY,NG,NI,NL,NO,NP,NZ,OM,PA,PE,PF,PG,PH,PK,PL,PR,PS,PT,PW,PY,QA,RO,RS,RU,SA,SB,SE,SG,SI,SK,SN,ST,SV,TG,TH,TN,TO,TR,TT,TW,TZ,UA,UG,UK,US,UY,UZ,VA,VE,VU,XK,YE,ZA 2017-11-14 07:06:20 576an-bio-rad-ana-screening-test 576AN Bio-Rad ANA Screening Test Bio-Rad ANA Screening Test Enzyme immunoassay to screen for panel of antinuclear antibodies (ANAs) associated with systemic rheumatic diseases (576 tests) Enzyme immunoassay to screen for panel of antinuclear antibodies (ANAs) involved in systemic rheumatic diseases (576 tests) Enzyme immunoassay to screen for panel of antinuclear antibodies (ANAs) associated with systemic rheumatic diseases (576 tests) /webroot/web/images/cdg/products/autoimmune/sku_thumb/global/aibu_576an_tn.jpg /webroot/web/images/cdg/products/autoimmune/sku_view/global/aibu_576an_view.jpg /webroot/web/images/cdg/products/autoimmune/sku_feature/global/aibu_576an_feature.jpg preview RepEx 576AN Enzyme immunoassay to screen for panel of antinuclear antibodies (ANAs) involved in systemic rheumatic diseases (576 tests) 09/21/09 12:08 PM 09/21/19 12:08 PM AE,AI,AL,AM,AR,AT,AU,AZ,BA,BD,BE,BF,BG,BH,BN,BO,BR,BW,CA,CH,CL,CM,CN,CO,CR,CY,CZ,DE,DK,DO,DZ,EC,EE,EG,EH,ER,ES,ET,FI,FM,FO,FR,GA,GE,GF,GH,GP,GR,GT,GU,HK,HN,HR,HT,HU,ID,IE,IL,IN,IS,IT,JM,JO,JP,KE,KH,KR,KW,KZ,LB,LI,LK,LT,LU,LV,MA,MD,MG,MK,ML,MO,MQ,MS,MT,MU,MX,MY,NG,NI,NL,NO,NP,NZ,OM,PA,PE,PF,PG,PH,PK,PL,PR,PS,PT,PW,PY,QA,RO,RS,RU,SA,SB,SE,SG,SI,SK,SN,ST,SV,TG,TH,TN,TO,TR,TT,TW,TZ,UA,UG,UK,US,UY,UZ,VA,VE,VU,XK,YE,ZA en CDG /CDG/Autoimmune/Systemic-Autoimmune-Testing--N N 0 false false false /prd/en/US/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=576AN&CartQuote=QT&quantity= false true false null false null /prd/en/US/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=576AN&AddToDefaultWishList=true&quantity= false false true true false true false true /prd/en/US/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=576AN&quantity= 576AN
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Bio-Rad ENA Plus Screening Test

96EP
Qualitative enzyme immunoassay for detection of antibodies against a panel of ENAs (96 tests)

3 96EP /templatedata/internet/product_SKU/data/CDG/Autoimmune/Systemic-Autoimmune-Testing--N/96EP_0921120819121.xml 96EP <?xml version="1.0" encoding="UTF-8"?> <Deployments> <Node Name="QA"> <Deployment Id="StandardMetadata.jc99dtr0jc99dtr1" Class="com.interwoven.livesite.lscs.model.LSCSDeploymentImpl" Instance="jc99dtr0jc99dtr1"> <Name>StandardMetadata</Name> <TargetEnviroment>QA</TargetEnviroment> <LastExecutionTime Class="java.util.Date" Month="1" DayOfMonth="12" DayOfWeek="5" Year="2018" Hour="1" Minute="40" Second="24" ZoneOffsetMillis="0" Time="1515721224134">Fri Jan 12 01:40:24 UTC 2018</LastExecutionTime> </Deployment> <Vpath>/default/main/bio-rad/WORKAREA/default/templatedata/internet/product_SKU/data/CDG/Autoimmune/Systemic-Autoimmune-Testing--N/96EP_0921120819121.xml</Vpath> <LastExecutionTime Class="java.util.Date" Month="1" DayOfMonth="12" DayOfWeek="5" Year="2018" Hour="1" Minute="40" Second="24" ZoneOffsetMillis="0" Time="1515721224134">Fri Jan 12 01:40:24 UTC 2018</LastExecutionTime> </Node> <Node Name="PRODWEST"> <Deployment Id="StandardMetadata.jcc1tny9jcc1tnya" Class="com.interwoven.livesite.lscs.model.LSCSDeploymentImpl" Instance="jcc1tny9jcc1tnya"> <Name>StandardMetadata</Name> <TargetEnviroment>PRODWEST</TargetEnviroment> <LastExecutionTime Class="java.util.Date" Month="1" DayOfMonth="12" DayOfWeek="5" Year="2018" Hour="22" Minute="51" Second="47" ZoneOffsetMillis="0" Time="1515797507848">Fri Jan 12 22:51:47 UTC 2018</LastExecutionTime> </Deployment> <Vpath>/default/main/bio-rad/WORKAREA/default/templatedata/internet/product_SKU/data/CDG/Autoimmune/Systemic-Autoimmune-Testing--N/96EP_0921120819121.xml</Vpath> <LastExecutionTime Class="java.util.Date" Month="1" DayOfMonth="12" DayOfWeek="5" Year="2018" Hour="22" Minute="51" Second="47" ZoneOffsetMillis="0" Time="1515797507848">Fri Jan 12 22:51:47 UTC 2018</LastExecutionTime> </Node> <Node Name="PRODEAST"> <Deployment Id="StandardMetadata.jcc1tny9jcc1tnyg" Class="com.interwoven.livesite.lscs.model.LSCSDeploymentImpl" Instance="jcc1tny9jcc1tnyg"> <Name>StandardMetadata</Name> <TargetEnviroment>PRODEAST</TargetEnviroment> <LastExecutionTime Class="java.util.Date" Month="1" DayOfMonth="12" DayOfWeek="5" Year="2018" Hour="23" Minute="54" Second="4" ZoneOffsetMillis="0" Time="1515801244985">Fri Jan 12 23:54:04 UTC 2018</LastExecutionTime> </Deployment> <Vpath>/default/main/bio-rad/WORKAREA/default/templatedata/internet/product_SKU/data/CDG/Autoimmune/Systemic-Autoimmune-Testing--N/96EP_0921120819121.xml</Vpath> <LastExecutionTime Class="java.util.Date" Month="1" DayOfMonth="12" DayOfWeek="5" Year="2018" Hour="23" Minute="54" Second="4" ZoneOffsetMillis="0" Time="1515801244985">Fri Jan 12 23:54:04 UTC 2018</LastExecutionTime> </Node> </Deployments> 09/21/09 12:08 PM en_US jc99dtjb 2017-11-14 07:06:20 true true internet/product_SKU CDG N en 09/21/19 12:08 PM 1515801567631 AE,AI,AL,AM,AR,AT,AU,AZ,BA,BD,BE,BF,BG,BH,BN,BO,BR,BW,CA,CH,CL,CM,CN,CO,CR,CY,CZ,DE,DK,DO,DZ,EC,EE,EG,EH,ER,ES,ET,FI,FM,FO,FR,GA,GE,GF,GH,GP,GR,GT,GU,HK,HN,HR,HT,HU,ID,IE,IL,IN,IS,IT,JM,JO,JP,KE,KH,KR,KW,KZ,LB,LI,LK,LT,LU,LV,MA,MD,MG,MK,ML,MO,MQ,MS,MT,MU,MX,MY,NG,NI,NL,NO,NP,NZ,OM,PA,PE,PF,PG,PH,PK,PL,PR,PS,PT,PW,PY,QA,RO,RS,RU,SA,SB,SE,SG,SI,SK,SN,ST,SV,TG,TH,TN,TO,TR,TT,TW,TZ,UA,UG,UK,US,UY,UZ,VA,VE,VU,XK,YE,ZA 2017-11-14 07:06:20 96ep-bio-rad-ena-plus-screening-test 96EP Bio-Rad ENA Plus Screening Test Bio-Rad ENA Plus Screening Test Qualitative enzyme immunoassay for detection of antibodies against a panel of ENAs (96 tests) Qualitative enzyme immunoassay for detection of antibodies against panel of ENAs (96 tests) Qualitative enzyme immunoassay for detection of antibodies against a panel of ENAs (96 tests) /webroot/web/images/cdg/products/autoimmune/sku_thumb/global/aibu_96ep_tn.jpg /webroot/web/images/cdg/products/autoimmune/sku_view/global/aibu_96ep_view.jpg /webroot/web/images/cdg/products/autoimmune/sku_feature/global/aibu_96ep_feature.jpg preview RepEx 96EP Qualitative enzyme immunoassay for detection of antibodies against panel of ENAs (96 tests) 09/21/09 12:08 PM 09/21/19 12:08 PM AE,AI,AL,AM,AR,AT,AU,AZ,BA,BD,BE,BF,BG,BH,BN,BO,BR,BW,CA,CH,CL,CM,CN,CO,CR,CY,CZ,DE,DK,DO,DZ,EC,EE,EG,EH,ER,ES,ET,FI,FM,FO,FR,GA,GE,GF,GH,GP,GR,GT,GU,HK,HN,HR,HT,HU,ID,IE,IL,IN,IS,IT,JM,JO,JP,KE,KH,KR,KW,KZ,LB,LI,LK,LT,LU,LV,MA,MD,MG,MK,ML,MO,MQ,MS,MT,MU,MX,MY,NG,NI,NL,NO,NP,NZ,OM,PA,PE,PF,PG,PH,PK,PL,PR,PS,PT,PW,PY,QA,RO,RS,RU,SA,SB,SE,SG,SI,SK,SN,ST,SV,TG,TH,TN,TO,TR,TT,TW,TZ,UA,UG,UK,US,UY,UZ,VA,VE,VU,XK,YE,ZA en CDG /CDG/Autoimmune/Systemic-Autoimmune-Testing--N N 0 false false false /prd/en/US/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=96EP&CartQuote=QT&quantity= false true false null false null /prd/en/US/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=96EP&AddToDefaultWishList=true&quantity= false false true true false true false true /prd/en/US/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=96EP&quantity= 96EP
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