Bio-Plex Pro Human IgA SARS-CoV-2 N/RBD/S1/S2 4-Plex Panel #12014665

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Overview

1 x 96-well, includes magnetic capture beads coupled with SARS-CoV-2 nucleocapsid, receptor-binding domain, spike 1, and spike 2 viral antigens, anti-human IgA detection antibody, ready-to-use positive control, ready-to-use negative control, wash buffer, assay buffer, serology sample diluent, detection antibody diluent, streptavidin-PE, 96-well flat-bottom plate, and sealing tape.

Safety Data Sheet

Safety Data Sheet

Description

Description

Contact and Expert

Questions? Ask a Bio-Plex Specialist.

The Bio-Plex Pro Human IgA SARS-CoV-2 S1/S2/N/RBD 4-plex panel detects IgA antibodies against SARS-CoV-2 nucleocapsid, receptor-binding domain, spike 1, and spike 2 viral protein and protein subunits. Measuring antibodies against each SARS-CoV-2 viral protein enables researchers to study the immune response to natural infection, vaccination, and levels of exposure in populations.

Features and Benefits

  • Comprehensive panel coverage — detects antibody response to four highly relevant SARS-CoV-2 viral antigens in a single well
  • High specificity and sensitivity — builds greater confidence in a positive or negative assessment in samples for seroprevalence studies
  • Fast protocol — results in less than 3 hours
  • Reproducibility — attain consistent results in your experiments with a robust, magnetic bead-based workflow
  • Streamlined data analysis — manage and analyze your data with ease using Bio-Plex Manager and Bio-Plex Data Pro Software

Kit Components

  • Magnetic capture beads coupled with SARS-CoV-2 viral antigens:
    • Nucleocapsid protein
    • Receptor-binding domain (RBD) protein subunit
    • Spike 1 protein
    • Spike 2 protein
  • Anti-human IgA detection antibody
  • Ready-to-use positive and negative controls
  • Wash buffer and assay buffer
  • Sample and detection antibody diluents
  • Streptavidin-PE
  • 96-well flat-bottom plate and sealing tape

Individual kit components can also be purchased to create custom assays.

Instrument Compatibility

Compatible with all xMAP Platforms:

*For Research Use Only. Not for use in diagnostic procedures.

Specifications

Specifications

Reactive species
Human
Intra-assay precision, %CV
<10%
Inter-assay precision, %CV
<15%
Clinical specificity
(n=282 negative samples)

Clinical specificity N = 100%, RBD = 98%, S1 = 100%, and S2 = 100%
Clinical sensitivity
(n=59 SARS-CoV-2 positive samples)

Clinical sensitivity (n=59 SARS-CoV-2 positive samples) N = 93%, RBD = 98%, S1 = 93%, and S2 = 95%
Compatible sample matrices
Serum, plasma

Documents

Documents

Number Description Options
10000133853
Bio-Plex Pro Human SARS-CoV-2 Serology Assays Instruction Manual
3208
Quantitative Bio-Plex Pro Human IgG, IgA, and IgM SARS-CoV-2 Serology Assays Using a Standard Curve Application Note
3299
Calibration Factors Using WHO International Standard (NIBSC 20/136) for Anti–SARS-CoV-2 Immunoglobulins Flier
3303
Bio-Plex Pro Human IgA, IgG, and IgM SARS-CoV-2 Serology Assay Performance in Freeze-Thawed and Refrigerated Serum, Plasma, and Saliva Samples

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