Pastorex™ Staph Plus

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Pastorex Staph Plus

Overview

Staphylococcus

Pastorex™ Staph Plus

Visibly More Sensitive

 


Pastorex Staph Plus disposable card.

 


A percentage of Staphylococcus aureus (mainly METHIR or MRSA strains resistant to methicillin) possess a capsule which can mask wall antigens (clumping factor and protein A) detected by agglutination tests.

 


Sensitivity is increased by the use of monoclonal antibodies1 directed against capsular polysaccharide antigens.

1Pasteur Institute patent.

 


Unmask METHI-R: Pastorex Staph Plus allows the simultaneous detection of cell wall antigens and capsular antigens of S. aureus.

Staphylococcus

Pastorex™ Staph Plus

Performance Characteristics

The performance of Pastorex Staph Plus has been evaluated in several different laboratories. A total of 568 strains of Staphylococcus aureus and 225 staphylococcal strains other than S. aureus were tested with the kit. Culture identification was carried out by using gram stain, catalase activity, and the coagulase tube test. Discrepant samples were subsequently tested by biochemical analysis and by a commercialized alternative rapid test. S. aureus strains were also checked for their susceptibility to methicillin. The results for sensitivity testing on methicillin-resistant S. aureus (MRSA) and methicillin-sensitive S. aureus (MSSA), as well as the total results for all S. aureus strains are reported in Table 1. The results for specificity testing on staphylococcal strains other than S. aureus are reported in Table 2.

Table 1. Performance of Pastorex Staph Plus on MRSA and MSSA Isolates

  Total Positive Negative Relative Sensitivity
MRSA 295* 293 2 99.3%
MSSA 272 272 0 100%
Total S. aureus 567* 565 2 99.6%


* One noninterpretable result was excluded


Table 2. Performance of Pastorex Staph Plus on Other Staphylococcal Strains

  Total Positive Negative Relative Sensitivity
Other Staphylococcal Strains 225 2 223 99.1%

A total of 225 staphylococcal isolates other than S. aureus, including S. epidermidis, S. haemolyticus, S. hominis, S. saprophyticus, S. schleiferi, S. lugdunensis, and other species, were also analyzed with Pastorex Staph Plus. A negative result was obtained for 223 of the 225 isolates, as shown in Table 2. The two discrepant results were identified as an S. lugdunensis and an S. hominis strain, and they were also positive with an alternative rapid test.

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The Bio-Rad Pastorex™ Staph Plus kit is a rapid latex agglutination test for the simultaneous detection of the fibrinogen affinity antigen (clumping factor), protein A, and the capsular polysaccharides of Staphylococcus aureus. A growing percentage of S. aureus (mainly methicillin-resistant (METHI-R or MRSA) strains) can elude detection in some agglutination tests because cell wall antigens (clumping factor and protein A) are masked. The Pastorex Staph Plus kit incorporates monoclonal antibodies to capsular polysaccharides as well as to cell wall antigens, thus reducing the risk of false negative results. This complete kit includes control, disposable cards, and sticks.

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Pastorex Staph Plus

56356
Detection of the fibrinogen affinity antigen, protein A, and capsular polysaccharides of Staphylococcus aureus by latex agglutination (50 tests)

56356 /templatedata/internet/product_SKU/data/CDG/Microbiology/Identification/56356_0921120859854.xml 56356 07/29/11 5:00 PM en_US true internet/product_SKU 2019-05-04 12:31:59 /default/main/bio-rad/STAGING AE,AI,AL,AM,AR,AT,AU,AZ,BA,BD,BE,BF,BG,BH,BN,BO,BR,BW,CA,CH,CL,CM,CN,CO,CR,CY,CZ,DE,DK,DO,DZ,EC,EE,EG,EH,ER,ES,ET,FI,FM,FO,FR,GA,GE,GF,GH,GP,GR,GT,GU,HK,HN,HR,HT,HU,ID,IE,IL,IN,IS,IT,JM,JO,JP,KE,KH,KR,KW,KZ,LB,LI,LK,LT,LU,LV,MA,MD,MG,MK,ML,MO,MQ,MS,MT,MU,MX,MY,NG,NI,NL,NO,NP,NZ,OM,PA,PE,PF,PG,PH,PK,PL,PR,PS,PT,PW,PY,QA,RO,RS,RU,SA,SB,SE,SG,SI,SK,SN,ST,SV,TG,TH,TN,TO,TR,TT,TW,TZ,UA,UG,UK,US,UY,UZ,VA,VE,VU,XK,YE,ZA,VN templatedata/internet/product_SKU/data/CDG/Microbiology/Identification/56356_en_1320569831_467.xml /default/main/bio-rad/WORKAREA/default jrtv5f09 2017-11-14 07:06:42 true jrtv5f09 templatedata/internet/product_SKU/data/CDG/Microbiology/Identification/56356_en_1320569831_467.xml CDG N /default/main/bio-rad en 07/29/21 5:00 PM 1555631412444 2019-05-04 12:31:59 /default/main/bio-rad/WORKAREA/default/templatedata/internet/product_SKU/data/CDG/Microbiology/Identification/56356_en_1320569831_467.xml 56356-pastorex-staph-plus 1 56356 Pastorex Staph Plus Pastorex Staph Plus Detection of the fibrinogen affinity antigen, protein A, and capsular polysaccharides of <i>Staphylococcus aureus</i> by latex agglutination (50 tests) /webroot/web/images/cdg/products/microbiology/sku_thumb/global/cmd_56356_tn.jpg /webroot/web/images/cdg/products/microbiology/sku_view/global/cmd_56356_view.jpg /webroot/web/images/cdg/products/microbiology/sku_feature/global/cmd_56356_feature.jpg Pastorex Staph Plus preview ,VN Alex Samodurov Pastorex Staph Plus Detection of the fibrinogen affinity antigen, protein A, and capsular polysaccharides of <i>Staphylococcus aureus</i> by latex agglutination (50 tests) 56356, microbiology, identification, immunological identification, latex agglutination tests, pastorex staph plus, pastorex staph plus 07/29/11 5:00 PM 07/29/21 5:00 PM AE,AI,AL,AM,AR,AT,AU,AZ,BA,BD,BE,BF,BG,BH,BN,BO,BR,BW,CA,CH,CL,CM,CN,CO,CR,CY,CZ,DE,DK,DO,DZ,EC,EE,EG,EH,ER,ES,ET,FI,FM,FO,FR,GA,GE,GF,GH,GP,GR,GT,GU,HK,HN,HR,HT,HU,ID,IE,IL,IN,IS,IT,JM,JO,JP,KE,KH,KR,KW,KZ,LB,LI,LK,LT,LU,LV,MA,MD,MG,MK,ML,MO,MQ,MS,MT,MU,MX,MY,NG,NI,NL,NO,NP,NZ,OM,PA,PE,PF,PG,PH,PK,PL,PR,PS,PT,PW,PY,QA,RO,RS,RU,SA,SB,SE,SG,SI,SK,SN,ST,SV,TG,TH,TN,TO,TR,TT,TW,TZ,UA,UG,UK,US,UY,UZ,VA,VE,VU,XK,YE,ZA,VN en CDG /CDG/Microbiology/Identification/ N 0 false null false $ null false false true true false USD true false true /prd/en/US/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=56356&quantity= false false /prd/en/US/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=56356&CartQuote=QT&quantity= 2413 false true false /prd/en/US/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=56356&AddToDefaultWishList=true&quantity= 41116100 null 56356
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Pastorex Staph Plus

56353
Detection of the fibrinogen affinity antigen, protein A, and capsular polysaccharides of Staphylococcus aureus by latex agglutination (5 x 50 tests)

56353 /templatedata/internet/product_SKU/data/CDG/Microbiology/Identification/56353_0921120859877.xml 56353 07/29/11 5:00 PM en_US true internet/product_SKU 2019-05-04 12:32:17 /default/main/bio-rad/STAGING AE,AI,AL,AM,AR,AT,AU,AZ,BA,BD,BE,BF,BG,BH,BN,BO,BR,BW,CA,CH,CL,CM,CN,CO,CR,CY,CZ,DE,DK,DO,DZ,EC,EE,EG,EH,ER,ES,ET,FI,FM,FO,FR,GA,GE,GF,GH,GP,GR,GT,GU,HK,HN,HR,HT,HU,ID,IE,IL,IN,IS,IT,JM,JO,JP,KE,KH,KR,KW,KZ,LB,LI,LK,LT,LU,LV,MA,MD,MG,MK,ML,MO,MQ,MS,MT,MU,MX,MY,NG,NI,NL,NO,NP,NZ,OM,PA,PE,PF,PG,PH,PK,PL,PR,PS,PT,PW,PY,QA,RO,RS,RU,SA,SB,SE,SG,SI,SK,SN,ST,SV,TG,TH,TN,TO,TR,TT,TW,TZ,UA,UG,UK,US,UY,UZ,VA,VE,VU,XK,YE,ZA,VN templatedata/internet/product_SKU/data/CDG/Microbiology/Identification/56353_en_1320569831_466.xml /default/main/bio-rad/WORKAREA/default jrtv5f08 2017-11-14 07:06:41 true jrtv5f08 templatedata/internet/product_SKU/data/CDG/Microbiology/Identification/56353_en_1320569831_466.xml CDG N /default/main/bio-rad en 07/29/21 5:00 PM 1555631412392 2019-05-04 12:32:17 /default/main/bio-rad/WORKAREA/default/templatedata/internet/product_SKU/data/CDG/Microbiology/Identification/56353_en_1320569831_466.xml 56353-pastorex-staph-plus 1 56353 Pastorex Staph Plus Pastorex Staph Plus Detection of the fibrinogen affinity antigen, protein A, and capsular polysaccharides of <i>Staphylococcus aureus</i> by latex agglutination (5 x 50 tests) /webroot/web/images/cdg/products/microbiology/sku_thumb/global/cmd_56353_tn.jpg /webroot/web/images/cdg/products/microbiology/sku_view/global/cmd_56353_view.jpg /webroot/web/images/cdg/products/microbiology/sku_feature/global/cmd_56353_feature.jpg Pastorex Staph Plus preview ,VN Alex Samodurov Pastorex Staph Plus Detection of the fibrinogen affinity antigen, protein A, and capsular polysaccharides of <i>Staphylococcus aureus</i> by latex agglutination (5 x 50 tests) 56353, microbiology, identification, immunological identification, latex agglutination tests, pastorex staph plus, pastorex staph plus 07/29/11 5:00 PM 07/29/21 5:00 PM AE,AI,AL,AM,AR,AT,AU,AZ,BA,BD,BE,BF,BG,BH,BN,BO,BR,BW,CA,CH,CL,CM,CN,CO,CR,CY,CZ,DE,DK,DO,DZ,EC,EE,EG,EH,ER,ES,ET,FI,FM,FO,FR,GA,GE,GF,GH,GP,GR,GT,GU,HK,HN,HR,HT,HU,ID,IE,IL,IN,IS,IT,JM,JO,JP,KE,KH,KR,KW,KZ,LB,LI,LK,LT,LU,LV,MA,MD,MG,MK,ML,MO,MQ,MS,MT,MU,MX,MY,NG,NI,NL,NO,NP,NZ,OM,PA,PE,PF,PG,PH,PK,PL,PR,PS,PT,PW,PY,QA,RO,RS,RU,SA,SB,SE,SG,SI,SK,SN,ST,SV,TG,TH,TN,TO,TR,TT,TW,TZ,UA,UG,UK,US,UY,UZ,VA,VE,VU,XK,YE,ZA,VN en CDG /CDG/Microbiology/Identification/ N 0 false null false $ null false false true true false USD true false true /prd/en/US/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=56353&quantity= false false /prd/en/US/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=56353&CartQuote=QT&quantity= 2413 false true false /prd/en/US/adirect/biorad?cmd=ajaxAddToCart&AddToCartProductID=56353&AddToDefaultWishList=true&quantity= 41116100 null 56353
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