Process Separations Webinars
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Ask an Expert — 15 Minutes | Past Webinars |
Ask an Expert — 15 Minutes
What You Need to Know About Packing Resins at Process Scale
Learn best practices and guidelines for successfully packing different types of chromatography resins. This includes incompressible resins like CHT Ceramic Hydroxyapatite Media as well as traditional compressible resins. CHT is an easy-to-use mixed-mode media and has high specific gravity, a rapid settling rate, and sensitivity to mechanical shear.
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Manufacturing a Recombinant Retrovirus — Downstream Purification Process Development
This webcast details the importance of resin screening, endonuclease treatment, process development, and the scale-up purification of a retrovirus-like particle intended for use in human subjects.
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Mixed-Mode Chromatography — Optimizing Target Purity and Recovery with Buffer Additives
This webcast showcases the unique selectivity of mixed-mode chromatography and detail the use of buffer additives for optimal target purity and yield.
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Efficient and Rapid Purification of E. coli Expressed Toxin Recombinant Protein Fragments
Dr. Lees presents the purification process for rTTHc using polymeric chromatography resins. rTTHc was expressed at high levels as a soluble, properly folded intracellular protein in Fina Bio proprietary Escherichia coli strain.
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Assessing Viral Clearance in Early Phase Process Development
Viral clearance studies are part of a multifaceted approach to ensure the safety of biopharmaceutical products. In order to prevent costly changes to a manufacturing process, it is important to assess each operation unit for its efficiency on the removal or inactivation of adventitious agents early on during downstream process development.
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Mixed-Mode Chromatography Resins for Biomolecule Purification
This webinar examines mixed-mode chromatography for biomolecule purification, which has emerged as a viable purification method for biomolecules that are otherwise difficult to purify using traditional platforms and other established means.
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Virus Purification Strategies and Considerations
Alternative strategies are needed for achieving efficient virus purification. This webinar will provide a snapshot of the resins considered, and the reasons for their selection, in order to achieve the required yield and purity.
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AEX Mixed-Mode Chromatography Resin for High Selectivity and Recovery
This webinar introduces the features of Nuvia aPrime 4A Resin, for high-purity and recovery over traditional chromatography resins.
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CHT Column Packing is Easier Than You Think
This webinar presents best practices and guidelines for packing CHT Ceramic Hydroxyapatite Media at a process scale.
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Nuvia HP-Q — A New High Performance AEX Resin
In this webinar, Dr. Jiali Liao presents case studies and design features to meet manufacturing demands.
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What you Need to Know About Packing Resins at Process-Scale
Dr. Mark A. Snyder, to learn best practices and guidelines for successfully packing different types of chromatography resins.
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Efficient and Rapid Purification of E. coli Expressed Toxin Recombinant Protein Fragments
Dr. Lees presents a purification process for rTTHc using polymeric chromatography resins.
Past Webinars
A Mixed-Mode Approach — Alternative to a Three-Step mAb Purification Process
In this webinar, we evaluate three monoclonal antibody purification workflows, compare alternatives to the traditional mAb three-step process focused on time and cost reduction, and we explore functionalities of mixed-mode resins.
Single-Step Column Purification for H1N1 Virus Using IEX Chromatography Resin
We discuss the development of vaccine production process against the Influenza A H1N1 subtype, using recently developed ion exchange chromatography resins.
Two-Step Purification of Low-Expressing Recombinant Exoprotein A Using Mixed-Mode Chromatography
This case study demonstrates an efficient purification workflow for a low-expressing recombinant protein.
Purification Strategies for Vaccine Production and Gene Therapy
Dr. Mark Snyder discusses strategies when developing purification methods for vaccine production and gene therapy.
A New Mixed-Mode Media for Biomolecule Purification
Drs. Yoshikawa and Snyder discuss application uses and provide selection guidelines to start your purification.
Integrating Viral Clearance into Your Process Development — A Case Study Using a Mixed‑Mode Chromatography Resin
Dr. Iheanacho and Dr. He present a case study using a DOE approach with a mixed-mode chromatography resin to evaluate viral clearance.
Large Biomolecule Purification with a New High-Performance Anion Exchange Resin
Drs. Kim and Liao introduce the design features of the Nuvia HP-Q Bead Matrix that help overcome purification challenges.