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In this webinar, Prof. Alexander Urban at the Stanford School of Medicine discusses how the Urban lab used the QX200 ddPCR System to investigate copy number variation in induced pluripotent stem cells (iPSCs), an offshoot their studies of normal and abnormal brain development and function related to autism. The prevalence of these types of somatic genomic variations in human tissues was only recently recognized, and their detection, exact mapping, and their effects on multiple levels of molecular control and regulation (e.g., DNA methylation, chromatin conformation, and gene expression patterns) have implications for the implementation of stem cell studies and possible therapeutic applications of stem cells