A Complete Solution for Legionella Testing

Print

Why Test for Legionella ?

fact sheet flyer

Legionellosis is an infection caused by Legionella bacteria in a water system, such as fountains, misting apparatus and cooling towers, particularly in health establishments, public buildings, and recreational water systems. The bacteria can cause acute pneumonia, Legionnaires' disease and a milder form of pulmonary infection, Pontiac fever. The actual number of Legionnaires' cases is thought to be much higher than reported as many people with pneumonia may not be tested for Legionella infection. Legionella pneumophila is responsible for approximately 90% of the clinical cases. Regular control of the presence of Legionella in water supply systems is an important way of preventing the disease. One of the most sensitive and specific methods developed for Legionella pneumophila testing is PCR (polymerase chain reaction). To ensure accuracy of data, commercially available detection methods must comply with specific requirements and validations recommended by government agencies and professional organizations that have published guidelines not only for the design, but also the commissioning requirements for cooling towers and water systems.

Bio-Rad’s iQ-Check method has been used for over 10 years to monitor Legionella in cooling towers and has been demonstrated to be a very powerful tool for industry and government agencies in outbreak surveillance.

Legionella crisis management timeline

Validation Scope

An official third party performance recognition

ISO (the International Organization for Standardization) is a worldwide federation of national standard bodies (ISO member bodies). The ISO TS 12869 describes the detection and enumeration of Legionella by PCR. The aim of this standard is to provide proof of performance of a Legionella PCR system that meets the highest level of quality management, from manufacturing of the product to the analysis of results. This helps build vendor credibility and buyer confidence by providing the marketplace with the assurance that performance claims are valid, credible and supported by high-quality, independent test data. This technical specification describes a method for the detection and quantification of Legionella spp. and L. pneumophila using PCR. It specifies general method requirements, performance evaluation requirements, and quality control requirements including inclusivity/exclusivity analysis, limit of detection, limit of quantification of PCR step, calibrating function, link to primary standard, and efficiency and robustness of extraction. The guidelines, minimum requirements and performance characteristics are intended to prove that the results are reliable and reproducible between different laboratories.

Validation Logo

Only methodologies certified by an independent and recognized third-party validation body can claim the ISO certification.

iQ-Check Legionella spp. and iQ-Check Legionella pneumophila Kits are NF VALIDATION certified according to NF T90-471 and ISO/TS 12869. The MD 15161-2013 Control of Legionella in Mechanical Systems Standard published by Public Works and Government Standards Canada (PWGSC) recommends the use of methods that are in accordance with the ISO TS 12869.

 - Public Health England report

iQ-Check Methods

The iQ-Check Legionella solution is an ISO/TS 12869 validated method based on amplification and detection of genomic sequences by real-time PCR. The Aquadien Kit is also an ISO/TS 12969 method that allows an optimal DNA extraction and purification from bacteria present in all types of water samples for PCR detection after a filtration step. The principle of the extraction is based on alkaline lysis of bacteria in presence of thermal shock and DNA purification using ultrafiltration. The Aquadien W2 Wash Solution is optimized for dirty water samples including those containing potential PCR inhibitors such as additives and chemicals used for water treatment. The iQ-Check Kit contains ready-to-use reagents required to perform the analysis of samples. Additional standards are provided for quantification. The iQ-Check method is based on the following steps:

iQ-Check Methods

Applications

  • Direct quantification of samples (with provided standards in line with the International Standard Reference Material according to ISO TS 12869)
  • Direct detection when screening for the presence or absence of Legionella according to ISO TS 12689
  • Testing large water resources, including water supply systems, industrial water systems (cooling towers), health establishments, public buildings, and recreational water systems
  • Management of complex (dirty) water samples with high-yield DNA extraction using the Aquadien Kit
  • Easy implementation by service labs
  • Detection of Legionella in biofilm, aerosol, and amoebae samples
  • Outbreak investigation for rapid results during a crisis
  • Real time monitoring of water systems with results in 4 hours

View our Legionella Solutions

iQ-Check Free DNA Removal Solution

One of the primary challenges when performing PCR for environmental water testing is the potential presence of free DNA, which can lead to an overestimation of the level of targeted DNA sequences. When quantifying Legionella, culture and PCR levels can differ from each other by up to 2 logs. To improve Legionella testing in water, a supplemental step using the iQ-Check Free DNA Removal Solution (FDRS) can be easily integrated in the Aquadien DNA Extraction Kit Workflow. FDRS is a non-carcinogenic safe way to remove free DNA from dead cells in environmental water samples. According to the principle, free DNA is degraded by an enzymatic treatment of the sample prior to DNA extraction, and inactivated by the Aquadien Extraction Kit R1 solution allowing for the extraction of DNA from intact and living cells. The inclusion of FDRS in the iQ-Check workflow reduces the occurrence of false positives.

Learn more

Standard Media and Confirmation Latex

Standard Media and Confirmation Latex Test

Bio-Rad, as a key partner for water testing, also manufactures a large range of products and solutions for Legionella testing such as GVPC and BCYE medium for the enumeration of Legionella according to ISO 11731 and latex kits for colony confirmation and serotyping. Contact your Bio-Rad sales specialist for more information.

Resources

  • Legionella Aquadien Standard DNA Extraction Protocol

  • Legionella Aquadien Short DNA Extraction Protocol

QCWK18BWLN4A [x-forwarded-proto] = [https] [accept-language] = [en-US,en;q=0.5] [x-forwarded-port] = [443] [x-forwarded-for] = [3.226.248.180, 10.232.18.115] [accept] = [text/html,application/xhtml+xml,application/xml;q=0.9,*/*;q=0.8] [seourl] = [/en-us/applications-technologies/complete-solution-for-legionella-testing] [x-amzn-trace-id] = [Root=1-5f732326-fff5bbe68593f24a18375e2e] [x-forwarded-server] = [lsds-prod-s.br.aws-livesite.io] [x-forwarded-host] = [www.bio-rad.com] [x-query-string] = [ID=QCWK18BWLN4A] [host] = [10.232.16.28:1776] [x-request-uri] = [/en-us/applications-technologies/complete-solution-for-legionella-testing] [connection] = [Keep-Alive] [accept-encoding] = [br,gzip] [user-agent] = [CCBot/2.0 (https://commoncrawl.org/faq/)] AppTech/AppTechDetails pageStyleKey internet/solutions_sub applications-technologies/complete-solution-for-legionella-testing FSD QCWK18BWLN4A Legionella Testing A Complete Solution for <em>Legionella</em> Testing /webroot/web/images/fsd/solutions/LEGIONELLA-th.jpg A Complete Solution for <em>Legionella</em> Testing Le Gao A Complete Solution for <em>Legionella</em> Testing Bio-Rad provides a complete system for the detection of <em>Legionella</em> in water, biofilm, and aerosol samples. 07/08/20 09:36 AM 08/08/30 11:39 AM AR,BO,BR,CA,CL,CO,CR,DO,EC,SV,GU,GT,HT,HN,JM,MX,NI,PA,PY,PE,PR,TT,US,UY,VE,AU,BD,BN,KH,CN,HK,IN,ID,JP,KR,MO,MY,FM,NP,NZ,PW,PG,PH,SG,SB,LK,TW,TH,TO,VU,VN,AL,DZ,AI,AM,AT,AZ,BH,BE,BA,BW,BG,BF,CM,HR,CY,CZ,DK,EG,ER,EE,ET,FO,FI,FR,GF,PF,GA,GE,DE,GH,GR,GP,HU,IS,IE,IL,IT,JO,KZ,KE,XK,KW,LV,LB,LI,LT,LU,MK,MG,ML,MT,MQ,MU,MD,MS,MA,NL,NG,NO,OM,PK,PS,PL,PT,QA,RO,RU,ST,SA,SN,RS,SK,SI,ZA,ES,SE,CH,TZ,TG,TN,TR,UG,UA,AE,UK,UZ,VA,EH,YE FSD /FSD/Applications/Legionella_Testing N 0 <div class="social-links"><a class="no-target-style" href="https://www.instagram.com/biorad_food_science" target="_blank" rel="noopener noreferrer"><img src="/webroot/web/images/general/Instagram.svg" alt="Food Science Instagram" width="20px" height="20px" /></a> <a class="no-target-style" href="https://www.youtube.com/playlist?list=PLrAEgIY86I6xTi-5C6r03UJRj7g_VEf-X" target="_blank" rel="noopener noreferrer"><img src="/webroot/web/images/general/YouTube.svg" alt="Food Science YouTube" width="20px" height="20px" /></a> <a class="no-target-style" href="https://twitter.com/biorad" target="_blank" rel="noopener noreferrer"><img src="/webroot/web/images/general/Twitter.svg" alt="Food Science Twitter" width="20px" height="20px" /></a> <a class="no-target-style" href="https://www.facebook.com/BioRadFSD" target="_blank" rel="noopener noreferrer"><img src="/webroot/web/images/general/Facebook.svg" alt="Food Science Facebook" width="20px" height="20px" /></a></div> <!--<div class="opt-module no-bttm-pddng opt-module-noborder"> <div class="opt-leaderboard legionella-module-feature linkpointer"> <div> <h2 class="white">iQ-Check Legionella Fact Sheet</h2> </div> <div><a class="bttn-block" onmousedown="dcsMultiTrack('DCS.dcsqry','?tgp_pcp_link_group=LeaderboardBanner&amp;tgp_pcp_link=Learn more','DCSext.tgp_pcp_link_group','','DCSext.tgp_pcp_link','','WT.dl','99999');" href="/en-us/category/geldoc-go-gel-imaging-system?ID=O494SO15"><span class="bttn-orange">Learn More</span></a></div> </div> </div>--> <div class="pagenav"><img src="/webroot/web/images/opt/prodnav-arrow-top.png" alt="" /> <table border="0"> <tbody> <tr> <td class="pagenavhead"> <h3>On This Page</h3> </td> <td class="pagenavfirst"><a onmousedown="dcsMultiTrack('DCS.dcsqry','?tgp_pcp_link_group=Page Nav&amp;tgp_pcp_link=Pathogen Detection','DCSext.tgp_pcp_link_group','','DCSext.tgp_pcp_link','','WT.dl','99999');" href="#vscope">Validation Scope</a></td> <td><a onmousedown="dcsMultiTrack('DCS.dcsqry','?tgp_pcp_link_group=Page Nav&amp;tgp_pcp_link=Microbial Testing','DCSext.tgp_pcp_link_group','','DCSext.tgp_pcp_link','','WT.dl','99999');" href="#icmethods">iQ-Check Methods</a></td> <td class="forcebreaks"><a onmousedown="dcsMultiTrack('DCS.dcsqry','?tgp_pcp_link_group=Page Nav&amp;tgp_pcp_link=Documents,'DCSext.tgp_pcp_link_group','','DCSext.tgp_pcp_link','','WT.dl','99999');" href="#resources">Resources</a></td> <td class="pagenavlast forcebreaks"><a onmousedown="dcsMultiTrack('DCS.dcsqry','?tgp_pcp_link_group=Page Nav&amp;tgp_pcp_link=Contact a Specialist','DCSext.tgp_pcp_link_group','','DCSext.tgp_pcp_link','','WT.dl','99999');" href="/featured/forms/en/TWAS-FSD-12-2020.html" class="bttn-block"><span class="bttn-orange">Consult with a Specialist</span></a></td> </tr> </tbody> </table> </div> <div class="opt-module opt-module-first opt-module-noborder no-bttm-pddng"> <h2>Why Test for <em>Legionella&nbsp;</em>?</h2> <img src="/webroot/web/images/fsd/solutions/Legionella-Testing/fact_sheet.png" alt="fact sheet flyer" caption="false" width="290" height="auto" class="right" /> <p class="p1">Legionellosis is an infection caused by <i>Legionella </i>bacteria in a water system, such as fountains, misting apparatus and cooling towers, particularly in health establishments, public buildings, and recreational water systems. The bacteria can cause acute pneumonia, Legionnaires' disease and a milder form of pulmonary infection, Pontiac fever. The actual number of Legionnaires' cases is thought to be much higher than reported as many people with pneumonia may not be tested for <i>Legionella</i> infection. <em>Legionella pneumophila</em> is responsible for approximately 90% of the clinical cases. Regular control of the presence of <em>Legionella </em>in water supply systems is an important way of preventing the disease. One of the most sensitive and specific methods developed for <em>Legionella pneumophila </em>testing is PCR (polymerase chain reaction). To ensure accuracy of data, commercially available detection methods must comply with specific requirements and validations recommended by government agencies and professional organizations that have published guidelines not only for the design, but also the commissioning requirements for cooling towers and water systems.</p> <p>Bio-Rad&rsquo;s iQ-Check method has been used for over 10 years to monitor <em>Legionella </em>in cooling towers and has been demonstrated to be a very powerful tool for industry and government agencies <strong></strong>in outbreak surveillance.</p> <img src="/webroot/web/images/fsd/solutions/Legionella-Testing/Legionella_Figure4-1.png" alt="Legionella crisis management timeline" caption="false" width="920" height="353" /></div> <div><a name="vscope"></a></div> <div class="opt-module opt-module-noborder bg-edf6e4"> <h2>Validation Scope</h2> <h3>An official third party performance recognition</h3> <p>ISO (the International Organization for Standardization) is a worldwide federation of national standard bodies (ISO member bodies). The ISO TS 12869 describes the detection and enumeration of <i>Legionella</i> by PCR. The aim of this standard is to provide proof of performance of a <em>Legionella </em>PCR system that meets the highest level of quality management, from manufacturing of the product to the analysis of results. This helps build vendor credibility and buyer confidence by providing the marketplace with the assurance that performance claims are valid, credible and supported by high-quality, independent test data. This technical specification describes a method for the detection and quantification of <em>Legionella </em>spp. and <em>L. pneumophila </em>using PCR. It specifies general method requirements, performance evaluation requirements, and quality control requirements including inclusivity/exclusivity analysis, limit of detection, limit of quantification of PCR step, calibrating function, link to primary standard, and efficiency and robustness of extraction. The guidelines, minimum requirements and performance characteristics are intended to&nbsp;prove that the results are reliable and reproducible between different laboratories.</p> <img src="/webroot/web/images/fsd/solutions/Legionella-Testing/Legionella_Figure4-2.png" alt="Validation Logo" class="right" caption="false" width="180" height="auto" /> <p>Only methodologies certified by an independent and recognized third-party validation body&nbsp;can claim the ISO certification.</p> <p>iQ-Check <em>Legionella </em>spp. and iQ-Check <em>Legionella pneumophila </em>Kits are NF VALIDATION certified according to NF T90-471 and ISO/TS 12869. The MD 15161-2013 Control of <em>Legionella </em>in Mechanical Systems Standard published by Public Works and Government Standards Canada (PWGSC) recommends the use of methods that are in accordance with the ISO TS 12869.</p> <p>&nbsp;<em>- <a href="https://drive.google.com/file/d/1AHPl80KOmuo0syvWg2ZiScU1w1TwYr4r/view" target="_blank" rel="noopener noreferrer">Public Health England report</a></em></p> </div> <div><a name="icmethods"></a></div> <div class="opt-module opt-module-noborder"> <h2 class="nextp">iQ-Check Methods</h2> <p>The iQ-Check <em>Legionella&nbsp;</em>solution is an ISO/TS 12869 validated method based on amplification and detection of genomic sequences by real-time PCR. The Aquadien Kit is also an ISO/TS 12969 method that allows an optimal DNA extraction and purification from bacteria present in all types of water samples for PCR detection after a filtration step. The principle of the extraction is based on alkaline lysis of bacteria in presence of thermal shock and DNA purification using ultrafiltration. The Aquadien W2 Wash Solution is optimized for dirty water samples including those containing potential PCR inhibitors such as additives and chemicals used for water treatment. The iQ-Check Kit contains ready-to-use reagents required to perform the analysis of samples. Additional standards are provided for quantification. The iQ-Check method is based on the following steps:</p> <img src="/webroot/web/images/fsd/solutions/Legionella-Testing/Legionella_Figure4-3.png" alt="iQ-Check Methods" width="920" height="auto" caption="false" /><br /><br /> <h3><strong>Applications</strong></h3> <ul class="list-header"> <li>Direct quantification of samples (with provided standards in line with the International Standard Reference Material according to ISO TS 12869)</li> <li>Direct detection when screening for the presence or absence of <em>Legionella</em> according to ISO TS 12689</li> <li>Testing large water resources, including water supply systems, industrial water systems (cooling towers), health establishments, public buildings, and recreational water systems</li> <li>Management of complex (dirty) water samples with high-yield DNA extraction using the Aquadien Kit</li> <li>Easy implementation by service labs</li> <li>Detection of <em>Legionella</em> in biofilm, aerosol, and amoebae samples</li> <li>Outbreak investigation for rapid results during a crisis</li> <li>Real time monitoring of water systems with results in 4 hours</li> </ul> <!--<h3><strong>Key Benefits of the iQ-Check <em>Legionella</em> Solution</strong></h3> <ul class="list-header"> <li><strong>Fast</strong> &mdash; 4 hr from sample to results and no confirmation needed</li> <li><strong>Reliable</strong> <span>&mdash;&nbsp;</span>Detects all <em>Legionella</em> species including viable but non culturable (VBNC) and intra amoebal <ul> <li>Includes positive/negative DNA controls and internal control</li> <li>Avoids contamination risk by not requiring post-PCR processing</li> </ul> </li> <li><strong>Convenient </strong>&mdash; all reagents provided with the kits and automated result interpretation (CFX Manager Software, IDE)</li> </ul>--> <p><a class="bttn-block no-target-style" href="/en-us/category/water-pcr-testing-kits?ID=LS5I4GKSY"><span class="bttn-orange">View our <em>Legionella</em> Solutions</span></a></p> <div class="dotteddivider dotteddividerdrk dotteddivider-less-top"></div> <h3 class="opt-subhead30 top-margin">iQ-Check Free DNA Removal Solution</h3> <p>One of the primary challenges when performing PCR for environmental water testing is the potential presence of free DNA, which can lead to an overestimation of the level of targeted DNA sequences. When quantifying <em>Legionella</em>, culture and PCR levels can differ from each other by up to 2 logs. To improve <em>Legionella</em> testing in water, a supplemental step using the iQ-Check Free DNA Removal Solution (FDRS) can be easily integrated in the Aquadien DNA Extraction Kit Workflow. FDRS is a non-carcinogenic safe way to remove free DNA from dead cells in environmental water samples. According to the principle, free DNA is degraded by an enzymatic treatment of the sample prior to DNA extraction, and inactivated by the Aquadien Extraction Kit R1 solution allowing for the extraction of DNA from intact and living cells. The inclusion of FDRS in the iQ-Check workflow reduces the occurrence of false positives.</p> <p><a class="bttn-block no-target-style" href="/FDRS#microbial"><span class="bttn-orange">Learn more</span></a></p> </div> <div class="opt-module opt-module-noborder no-bttm-pddng bg-023737 white"><img src="/webroot/web/images/fsd/solutions/Legionella-Testing/Legionella_Figure4-4.png" alt="Standard Media and Confirmation Latex" width="180" class="right" caption="false" /> <h2 class="nextp">Standard Media and Confirmation Latex Test</h2> <p>Bio-Rad, as a key partner for water testing, also manufactures&nbsp;a large range of products and solutions for <em>Legionella </em>testing such as GVPC and BCYE medium for the enumeration of <em>Legionella </em>according to ISO 11731 and latex kits for colony confirmation and serotyping. Contact your Bio-Rad sales specialist for more information.</p> </div> <div><a name="resources"></a></div> <div class="opt-module no-bttm-pddng optresources-bg bttm-margin-neg"> <h2>Resources</h2> <ul class="list-set list-three-col list-set-th"> <li><a class="no-target-style" href="/webroot/web/pdf/fsd/literature/FSD_17932.pdf" target="_blank" rel="noopener noreferrer"><img src="/webroot/web/images/fsd/solutions/cannabis-testing/bulletin_17932_tn.png" alt="New Booklet 17932" width="85" height="110" caption="false" /></a> <h3><a class="no-target-style" href="/webroot/web/pdf/fsd/literature/FSD_17932.pdf" target="_blank" rel="noopener noreferrer">Water Safety and Quality Reference Guide</a> <br /><span class="filesize">(PDF&nbsp;4.4&nbsp;MB)</span></h3> </li> <li><a href="/webroot/web/pdf/fsd/literature/Bulletin_16414.pdf" target="_blank" rel="noopener noreferrer"><img src="/webroot/web/images/fsd/solutions/cannabis-testing/bulletin_16414_tn.png" alt="Brochure 16414" caption="false" width="85" height="110" /></a> <h3><a href="/webroot/web/pdf/fsd/literature/Bulletin_16414.pdf" target="_blank" rel="noopener noreferrer"><em>Legionella</em> Testing Solution Brochure</a><br /><span class="filesize">(PDF&nbsp;717 KB)</span></h3> </li> <li><span class="filesize"><span class="filesize"><a href="/webroot/web/pdf/fsd/literature/Bulletin_7021.pdf" target="_blank" rel="noopener noreferrer"><img src="/webroot/web/images/fsd/solutions/cannabis-testing/bulletin_7021_tn.png" alt="FDRS 7021" width="85" height="110" caption="false" /></a></span></span> <h3><a href="/webroot/web/pdf/fsd/literature/Bulletin_7021.pdf" target="_blank" rel="noopener noreferrer">iQ-Check Free DNA Removal Solution for <em>Legionella</em> Brochure</a><br /><span class="filesize">(PDF 1.1 MB)</span></h3> </li> <li><span class="filesize"><span class="filesize"><a href="/webroot/web/pdf/fsd/literature/iQ-Check_Legionella_Fact_Sheet.pdf" target="_blank" rel="noopener noreferrer" class="no-target-style"><img src="/webroot/web/images/fsd/solutions/cannabis-testing/Fact_sheet_flyer-th.png" alt="Fact sheet flyer" width="85" height="110" caption="false" /></a></span></span> <h3><a href="/webroot/web/pdf/fsd/literature/iQ-Check_Legionella_Fact_Sheet.pdf" target="_blank" rel="noopener noreferrer" class="no-target-style">iQ-Check <em>Legionella</em>&nbsp;Fact Sheet</a> <br /><span class="filesize">(PDF&nbsp;569&nbsp;KB)</span></h3> </li> <li><a href="https://info.bio-rad.com/water-testing-solutions-webinar.html?WT.mc_id=180508024331" target="_blank" rel="noopener noreferrer"><img src="/webroot/web/images/fsd/solutions/cannabis-testing/Legionella_Testing_Solution.png" width="85" height="110" caption="false" alt="Legionella Testing Solution" /></a> <h3><a href="https://info.bio-rad.com/water-testing-solutions-webinar.html?WT.mc_id=180508024331" target="_blank" rel="noopener noreferrer"><em>Legionella</em> Risk Management Webinar</a></h3> </li> <!--<li><a href="https://drive.google.com/file/d/0ByMtbykW3GhfYzBXV083R2Y0UUU/view" target="_blank" rel="noopener noreferrer" title="Legionella Risk Management"><img src="/webroot/web/images/fsd/solutions/cannabis-testing/Legionella_Risk_Management.png" alt="iQ-Check Real-Time PCR Solution Brochure" width="85" height="110" caption="false" /></a> <h3><a href="https://drive.google.com/file/d/0ByMtbykW3GhfYzBXV083R2Y0UUU/view" target="_blank" rel="noopener noreferrer">Environment and Water Testing Management Webinar</a></h3> </li>--></ul> <div class="dotteddivider dotteddividerdrk dotteddivider-less-top"></div> <ul class="list-set list-two-col"> <li><iframe width="437" height="245" src="https://www.youtube.com/embed/CPe5W96nrVQ" title="Legionella Aquadien Standard DNA Extraction Protocol" _fsrb="true" frameborder="0" allow="accelerometer; autoplay; encrypted-media; gyroscope; picture-in-picture" allowfullscreen=""></iframe> <h3>Legionella Aquadien Standard DNA Extraction Protocol</h3> </li> <li><iframe width="437" height="245" src="https://www.youtube.com/embed/GyxBpzcyjWQ" title="Legionella Aquadien Short DNA Extraction Protocol" _fsrb="true" frameborder="0" allow="accelerometer; autoplay; encrypted-media; gyroscope; picture-in-picture" allowfullscreen=""></iframe> <h3>Legionella Aquadien Short DNA Extraction Protocol</h3> </li> </ul> <script type="text/javascript" src="/webroot/web/js/apptech-opt-conveter-min.js"></script> <script type="text/javascript" src="/webroot/web/js/jquery.bxslider-min.js"></script> <script type="text/javascript" src="/webroot/web/js/jquery.fitvids-min.js"></script> <script>// <![CDATA[ $('head').append('<link rel="stylesheet" href="/webroot/web/css/bxslider-min.css" type="text/css" media="screen" />'); $(window).load(function() { var sliderHm = $('.slider').bxSlider({ onSliderLoad: function () { $('.bx-wrapper').hover( function () { $('.bx-controls-direction').fadeIn(300); } , function () { $('.bx-controls-direction').hide(); } ); $('.bx-pager-item a').click(function(e) { var i = $(this).attr('data-slide-index'); sliderHm.goToSlide(i); return false; } ); } }); $(document).keydown(function(e){ if (e.keyCode == 39) // Right arrow { sliderHm.goToNextSlide(); return false; } else if (e.keyCode == 37) // left arrow { sliderHm.goToPrevSlide(); return false; } }); $(window).resize( function() { if(sliderHm) { sliderHm.destroySlider(); sliderHm.reloadSlider(); } }).trigger("resize"); }); // ]]></script> </div> 1
Sign Up for Bio-Rad Updates!
Enter your email address below to receive your choice of the latest news, promotions, and more.
QCWK18BWLN4A [x-forwarded-proto] = [https] [accept-language] = [en-US,en;q=0.5] [x-forwarded-port] = [443] [x-forwarded-for] = [3.226.248.180, 10.232.18.115] [accept] = [text/html,application/xhtml+xml,application/xml;q=0.9,*/*;q=0.8] [seourl] = [/en-us/applications-technologies/complete-solution-for-legionella-testing] [x-amzn-trace-id] = [Root=1-5f732326-fff5bbe68593f24a18375e2e] [x-forwarded-server] = [lsds-prod-s.br.aws-livesite.io] [x-forwarded-host] = [www.bio-rad.com] [x-query-string] = [ID=QCWK18BWLN4A] [host] = [10.232.16.28:1776] [x-request-uri] = [/en-us/applications-technologies/complete-solution-for-legionella-testing] [connection] = [Keep-Alive] [accept-encoding] = [br,gzip] [user-agent] = [CCBot/2.0 (https://commoncrawl.org/faq/)] AppTech/AppTechDetails pageStyleKey applications-technologies/complete-solution-for-legionella-testing FSD true https://www.bio-rad-antibodies.com https://www.bio-rad.com 03/26/14 02:17 PM en_US true internet/generic 2020-09-24 00:52:26 /default/main/bio-rad/STAGING 1385504243813 US templatedata/internet/generic/data/en_US/GNL/page_generic_footer_b2c_1385505294_US.xml page_generic_footer_b2c /default/main/bio-rad/WORKAREA/default jc7v8okm 2017-10-27 13:13:40 true Done jc7v8okm templatedata/internet/generic/data/en_US/GNL/page_generic_footer_b2c_1385505294_US.xml GNL N /default/main/bio-rad en_US 11/27/23 02:18 PM 1597678086809 2020-09-24 00:52:26 /default/main/bio-rad/WORKAREA/default/templatedata/internet/generic/data/en_US/GNL/page_generic_footer_b2c_1385505294_US.xml footer-page 1 1385504243813 page_generic_footer_b2c <div class="col"> <h4>Support</h4> <ul> <li><a class="wtclass linkgeneration" href="_brcDomain/_locale/life-science-research/support?ID=1140">Life Science Support</a></li> <li><a class="wtclass linkgeneration" href="_acdDomain/technical-support.html">Antibodies Support</a></li> <li><a class="wtclass linkgeneration" href="_brcDomain/_locale/life-science-research/purchase-service-programs/expert-care-service?ID=1383780912356">Expert Care Service</a></li> <li><a class="wtclass linkgeneration" href="_brcDomain/contact">Contact Us</a></li> </ul> </div> <div class="col"> <h4>Documents</h4> <ul> <li><a class="wtclass linkgeneration" href="_brcDomain/_locale/literature-library">Literature Library</a></li> <li><a class="wtclass linkgeneration" href="_brcDomain/_locale/life-science-research/support/certificate-of-analysis">Certificate of Analysis</a></li> <li><a class="wtclass" href="https://myeinserts.qcnet.com/" target="_blank" rel="noopener noreferrer">QC Inserts</a></li> <li><a class="wtclass linkgeneration" href="_brcDomain/featured/en/quality-management-systems-certificates.html">Quality Certification</a></li> </ul> </div> <div class="col"> <h4>Ordering</h4> <ul> <li><a class="wtclass linkgeneration" href="_brcDomain/_locale/my-bio-rad">Quick Order</a></li> <li><a id="footer_orderLink" class="orderhistoryLink wtclass" href="javascript:void(0);">Order History</a></li> <li><a class="wtclass" id="footer_quoteLink" href="javascript:void(0);">Quote History</a></li> <li><a class="wtclass linkgeneration" href="_brcDomain/_locale/my-bio-rad">My Bio-Rad</a></li> <li><a class="wtclass linkgeneration" href="_brcDomain/_locale/life-science-research/purchase-service-programs/supply-center-program?ID=1383773882551">Supply Centers</a></li> </ul> </div> <div class="col"> <h4>Our Products</h4> <ul> <li><a class="wtclass linkgeneration" href="_brcDomain/_locale/life-science-research?ID=1100">Life Science Research</a></li> <li><a class="wtclass linkgeneration" href="_acdDomain/">Antibodies</a></li> <li><a class="wtclass linkgeneration" href="_brcDomain/_locale/clinical-diagnostics?ID=1200">Clinical Diagnostics</a></li> <li><a class="wtclass linkgeneration" href="_brcDomain/_locale/process-separations?ID=1400">Process Separations</a></li> <li><a class="wtclass linkgeneration" href="_brcDomain/_locale/food-science?ID=1475">Food Science</a></li> <li><a class="wtclass linkgeneration" href="_brcDomain/_locale/education?ID=1450">Life Science Education</a></li> </ul> </div> <div class="col" style="padding-right: 0;"> <h4>Company</h4> <ul> <li><a class="wtclass linkgeneration" href="_brcDomain/_locale/corporate/about-bio-rad?ID=1003">About Bio-Rad</a></li> <li><a class="wtclass linkgeneration" href="_brcDomain/_locale/corporate/careers?ID=1004">Careers</a></li> <li><a class="wtclass linkgeneration" href="_brcDomain/_locale/corporate/investor-relations?ID=1007">Investor Relations</a></li> <li><a class="wtclass linkgeneration" href="_brcDomain/_locale/corporate/newsroom?ID=1006">Newsroom</a></li> <li><a class="wtclass linkgeneration" href="_acdDomain/blog/">Blog</a></li> <li><a class="wtclass" target="_blank" href="https://www.bioradiations.com" rel="noopener noreferrer">Bioradiations</a></li> <li> <div class="social"> <ul> <li><a class="no-target-style brconly wtclass" href="https://www.linkedin.com/company/bio-rad?trk=top_nav_home" target="_blank" rel="noopener noreferrer"><img src="https://www.bio-rad.com/webroot/web/images/general/icons/linkedin_round_40x40.png" alt="Bio-Rad LinkedIn" width="20" height="20" /></a> <a class="no-target-style bracd wtclass" style="display: none;" href="https://www.linkedin.com/company/bio-rad-antibodies" target="_blank" rel="noopener noreferrer"><img src="https://www.bio-rad.com/webroot/web/images/general/icons/linkedin_round_40x40.png" alt="Bio-Rad Antibodies LinkedIn" width="20" height="20" /></a></li> <li><a class="no-target-style brconly wtclass" href="https://www.youtube.com/user/BioRadLifeScience" target="_blank" rel="noopener noreferrer"><img src="https://www.bio-rad.com/webroot/web/images/general/icons/youtube-icon-rnd-40x40.png" alt="Bio-Rad YouTube" width="20" height="20" /></a> <a class="no-target-style bracd wtclass" style="display: none;" href="https://www.youtube.com/playlist?list=PLrAEgIY86I6w1jajKp3O9RQJEvJZ2ux0I" target="_blank" rel="noopener noreferrer"><img src="https://www.bio-rad.com/webroot/web/images/general/icons/youtube-icon-rnd-40x40.png" alt="Bio-Rad Antibodies YouTube" width="20" height="20" /></a></li> <li><a class="no-target-style brconly wtclass" href="https://twitter.com/BioRadLifeSci" target="_blank" rel="noopener noreferrer"><img src="https://www.bio-rad.com/webroot/web/images/general/icons/twitter_round_40x40.png" alt="Bio-Rad Twitter" width="20" height="20" /></a> <a class="no-target-style bracd wtclass" style="display: none;" href="https://twitter.com/BioRadAbs" target="_blank" rel="noopener noreferrer"><img src="https://www.bio-rad.com/webroot/web/images/general/icons/twitter_round_40x40.png" alt="Bio-Rad Antibodies Twitter" width="20" height="20" /></a></li> <li><a class="no-target-style brconly wtclass" href="https://www.facebook.com/biorad/" target="_blank" rel="noopener noreferrer"><img src="https://www.bio-rad.com/webroot/web/images/general/icons/facebook-icon-rnd-40x40.png" alt="Bio-Rad Facebook" width="20" height="20" /></a> <a class="no-target-style bracd wtclass" style="display: none;" href="https://www.facebook.com/BioRadAntibodies" target="_blank" rel="noopener noreferrer"><img src="https://www.bio-rad.com/webroot/web/images/general/icons/facebook-icon-rnd-40x40.png" alt="Bio-Rad Antibodies Facebook" width="20" height="20" /></a></li> <li><a class="no-target-style wtclass" href="https://www.instagram.com/bioradlabs/" target="_blank" rel="noopener noreferrer"><img src="https://www.bio-rad.com/webroot/web/images/general/icons/instagram-icon-rnd-40x40.png" alt="Bio-Rad Instagram" width="20" height="20" /></a></li> <li><a class="no-target-style wtclass" href="https://uk.pinterest.com/BioRadAbs/" target="_blank" rel="noopener noreferrer"><img src="https://www.bio-rad.com/webroot/web/images/general/icons/pinterest40x40.png" alt="Bio-Rad Pinterest" width="20" height="20" /></a></li> </ul> </div> </li> </ul> </div> 0 /webroot/web/html footer_page_b2c_en_US.html /webroot/web/html/footer_page_b2c_en_US.html Karen Moss Footer page Footer 03/26/14 02:17 PM 11/27/23 02:18 PM US en GNL /en_US/GNL N 0 en-us Home <script type="text/javascript">$(document).ready(function() { var region = $("#headlangID .lang strong").html(); $(".footer-nav > a:nth-child(3)").after(" | <a href='https://www.bio-rad.com/webroot/web/html/featured/en/web-accessibility.html' id='regionlink'>Web Accessibility</a>");});</script>Trademarks Site Terms Terms & Conditions Imprint EU Recycle Program Transparency Information Privacy Change Cookie Setting <script type="text/javascript">$(document).ready(function () {$(".links2").append('<style>.social-links-br {float: left;margin-right: 10px;}.social-links-br img {width: 20px;height: 20px;margin-right: 5px}</style><div class="social-links-br"><a class="no-target-style" href="https://www.linkedin.com/company/bio-rad?trk=top_nav_home" target="_blank"><img src="/webroot/web/images/general/icons/linkedin_round_40x40.png" alt="Bio-Rad LinkedIn"></a><a class="no-target-style" href="https://www.youtube.com/user/BioRadLifeScience" target="_blank"><img src="/webroot/web/images/general/icons/youtube-icon-rnd-40x40.png" alt="Bio-Rad YouTube"></a><a class="no-target-style" href="https://twitter.com/BioRadLifeSci" target="_blank"><img src="/webroot/web/images/general/icons/twitter_round_40x40.png" alt="Bio-Rad Twitter"></a><a class="no-target-style" href="https://www.facebook.com/biorad/" target="_blank"><img src="/webroot/web/images/general/icons/facebook-icon-rnd-40x40.png" alt="Bio-Rad Facebook"></a><a class="no-target-style" href="https://www.instagram.com/bioradlabs/" target="_blank"><img src="/webroot/web/images/general/icons/instagram-icon-rnd-40x40.png" alt="Bio-Rad Instagram"></a></div>');});</script>&copy; {0} Bio-Rad Laboratories, Inc. This page was last edited on {0} true True GTM-MJ2DN2S us US en FSD food-science life-science-research /prd/en/US/direct/biorad?ts=1&cmd=OrdersWorkspaceDisplay /prd/en/US/direct/biorad?ts=1&cmd=QuotesWorkspaceDisplay /prd/en/US/direct/biorad?ts=1&cmd=InvoiceWorkspaceDisplay&_Tab=Invoice false false true true false 1040988879 LHsYCOu_wQMQz_Ww8AM window.google_tag_params true 272-THL-329 EU_COOKIE_PREFS CartID_ WT_FPC <script type="text/javascript">$.ajax({url: document.location.protocol + '//munchkin.marketo.net/munchkin.js',dataType: 'script',cache: true,success: function() {Munchkin.init('272-THL-329');}});</script> <script type="text/javascript" src="https://www.bio-rad.com/evportal/framework/skins/evolution/js/proxyMunchkin.js"></script> 2020 {"country":"us","b2b_punch_out_mode":"","pageType":"App & Tech Detail","user_id":"","visitorLoginState":false,"visitorType":"","sessionType":"B2C","language":"en","vertical":"FSD","b2b_org_id":""} 0 0 0