What a Difference a d Makes

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  • Droplet Digital™ PCR (ddPCR™) stands as a groundbreaking technology that has revolutionized the nucleic acid detection with nucleic acid quantification. Since its inception, ddPCR technology has earned acclaim as transformative technology, ushering in remarkable enhancements in the precision and sensitivity of nucleic acid detection. It’s the “d” in ddPCR that makes the difference…

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“d” for Unrivaled Differentiator

  • In the landscape of digital PCR solutions, Bio-Rad's ddPCR technology emerges as a pioneering force, reshaping the standards for researchers worldwide. What sets ddPCR technology apart is its innovative approach leveraging droplets, which transcends conventional boundaries to redefine precision, accuracy, and simplicity in nucleic acid quantification. Unlike traditional digital PCR methods, ddPCR technology introduces a transformative approach that empowers researchers to confidently detect and quantify rare targets, discern subtle variations, and uncover pivotal insights. This game-changing attribute ensures consistent results, often elusive with other platforms, and establishes ddPCR technology as a trailblazer in the field of molecular research.

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“d” for Droplet: Precision in Every Drop

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  • Precision is at the heart of ddCPR technology. By encapsulating individual DNA or RNA molecules into droplets, ddPCR technology achieves unparalleled precision and accuracy in nucleic acid quantification. Each droplet becomes a micro-reaction chamber, enabling absolute quantification with digital precision. This technology's hallmark is its ability to divide a sample into thousands of droplets, making it exceptionally powerful for detecting rare mutations, quantifying low-abundance targets, and delivering robust results even in challenging samples.

“d” for Data-Driven Insights

  • In the age of big data, Bio-Rad's ddPCR technology stands as a data-driven powerhouse. It generates rich datasets that empower researchers to draw deeper insights from their experiments. With a vast array of digital data points, ddPCR technology allows for the precise analysis of target concentrations, absolute quantification, and statistical confidence. Researchers can harness these data-driven insights to make informed decisions, identify subtle variations, and uncover critical trends, ultimately accelerating scientific discovery.

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“d” for Delivering Simplified Workflow

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  • Bio-Rad's ddPCR technology not only ensures precision but also streamlines the experimental process. Its droplet-based methodology simplifies the workflow, reducing complexity and making it more accessible to researchers. Researchers can achieve accurate results without the need for intricate procedures or extensive training, making it an invaluable tool for labs seeking straightforward and dependable nucleic acid quantification.

“d” for Dependable

  • In the realm of nucleic acid analysis, Bio-Rad's ddPCR technology is a dependable and trusted ally. Researchers worldwide rely on its consistency and reproducibility to obtain reliable results, experiment after experiment. The robustness of ddPCR has made it a go-to choice for critical applications such as disease diagnostics, gene expression analysis, and copy number variation studies. Its reliability has earned the trust of scientists, making it an indispensable tool in molecular research where accuracy and dependability are paramount.

  • More than 8300 published studies have described research breakthroughs using Droplet Digital™ PCR technology

Explore the ddPCR Portfolio

With its ability to deliver precise and reliable data, ddPCR has become a valuable tool in a wide range of applications, such as cell gene therapy, gene expression analysis, rare mutation detection, copy number variation and many more.

Testimonials and Insights

  • Alec Morley

    "Droplet digital PCR is a powerful technology that has transformed the field of nucleic acid analysis. Its ability to accurately quantify nucleic acids in complex samples has broad applications in research and clinical diagnostics, including cancer detection and monitoring, infectious disease diagnosis, and prenatal testing."

    Dr. Alec Morley,
    Director of the Centre for Biomedical Engineering at the University of Auckland

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  • Gary Pestano

    "By utilizing ddPCR, we can analyze ctDNA levels as early as 3 weeks post-treatment. These results have high prognostic value. We see better outcomes in patients that clear ctDNA than those that do not."

    Gary Pestano, PhD,
    Chief Development Officer at Biodesix

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  • Tami Sivy, Ph.D.

    "One thing we have established however is our methods: The sampling and ddPCR-based testing protocols are working great and we’re confident in the quality of data we’re collecting."

    Tami Sivy, Ph.D.,
    Saginaw Valley State University (SVSU), Michigan

    Learn More

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