NGC Pump and Mixer Modules and Components

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Overview

The pump kits used in the NGC Systems are interchangeable. The pump kits contain fully assembled pump heads with seals and check valves installed for fast, easy pump head changes. Mixers ensure improved gradient quality for more accurate separations.
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Description

Description

The family of NGC Medium-Pressure Chromatography Systems can be personalized with the addition of specific modules pertinent to your application and throughput needs.

The NGC Chromatography System can have up to three high-precision pumps: two system or gradient pumps (pump A and pump B), and one sample pump. These pumps enable the formation of gradients and delivery of predefined volumes of buffers and samples at precise flow rates and pressures, ensuring the reproducible, automated, and scalable purification of proteins and biological samples. The F10 NGC System Pumps are standard with all 10 ml NGC Systems, the F100 NGC System Pumps come standard with all 100 ml NGC Systems, and produce automated proportioned solutions and flow rates.

The NGC Sample Pump Module comes standard with the NGC Discover 10 and NGC Discover 10 Pro Systems and enables the injection of large sample volumes, or allows repetitive, accurate, and consistent multiple loadings from a single sample stock. The sample pump can also be added into any vacant slot in any NGC System as an add-on. All pumps can be controlled to avoid overpressure and the sample pump module also includes an integrated pressure sensor that protects the column and media from overpressure.

The NGC Mixer Module comes standard with all preconfigured NGC Systems and can be fitted with different size barrels to provide optimally homogenized buffer gradients created by the two system pumps. Barrel extenders provide efficient gradient mixing at higher flow rates.

Features and Benefits of NGC Sample Pump and Mixer Modules

  • The NGC F10 Pump enables lower flow rates of 0.001–10 ml/min at 3,650 psi (252 bar, 25.2 MPa)
  • The NGC F100 Pump enables higher flow rates of 0.01–100 ml/min at 1,450 psi (100 bar, 10 Mpa)
  • The NGC Mixer Module has interchangeable mixing chambers for efficient gradient mixing at higher flow rates
  • The NGC Sample Pump Module eliminates the risk of contaminating system pumps with viscous protein samples and enables automated loading of large sample volumes, either directly to the column or via a DynaLoop™ Sample Loop, at a flow rate of up to 100 ml/min at 1,450 psi
  • The sample pump has an integrated pressure sensor that protects columns and media from overpressure

Applications and Uses of NGC Sample Pump and Mixer Modules

  • NGC System Pumps enable the formation of gradients at different flow rates according to your needs
  • The sample pump controls and automates sample application, thereby increasing accuracy between experimental runs

More Information

Other modules may be added to your NGC Medium-Pressure Chromatography System to increase functionality and automation. For instance, plug in the buffer blending valve module for automated inline buffer preparation and generation of pH gradients for quick pH scouting. Or add the column switching valve module for 10 ml or 100 ml systems to connect up to five columns and enable quick and easy column scouting and cleaning, either under normal conditions or reverse flow, without the need to re-plumb the system.

ChromLab Software makes it easy to incorporate the added modules into fluidic schemes and methods to operate and monitor their individual status during automated, complex separations. Additional modules are described on the NGC Chromatography Modules and Accessories page.

Ordering

Ordering

items

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7884002
Pkg of 1, includes 10 ml/min system pump kit with the necessary tubing and fittings, for creating buffer gradients
ngc-f100-pump-module-788-4003-thumb-ngc-100-medium-pressure-chromatography-systems.jpg
7884003
Pkg of 1, includes 100 ml/min system pump kit with the necessary tubing and fittings, for creating buffer gradients
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7884004
Pkg of 1, includes 100 ml/min sample pump kit with the necessary tubing and fittings, for automated large-volume sample application
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(Discontinued) NGC Mixer Module
7884018

Pkg of 1, includes 10 ml/min kit with the necessary tubing and fittings, upgradable for use with F100 systems

Accessories

Accessories

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7884020
Pkg of 1, 263 µl base and top assembly, included with all 10 ml NGC Systems
ngc-f10-mixer-barrel-750-ul-body-small-SKU-788-4021-thumb.jpg
7884021
Pkg of 1, 750 µl extension barrel for F10 263 µl mixer, part of the NGC Scout™ 10, NGC Discover™ 10 Series
ngc-f10-mixer-barrel-2-ml-body-small-SKU-788-4022-thumb.jpg
7884022
Pkg of 1, 2 ml extension barrel for F10 263 µl mixer body, optional part
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7885003
The NGC System Pump Maintenance Kit includes pump head seals, wash behind seals, wash behind check valves, check valves, O-rings, and small and large disks for servicing one NGC Chromatography F10 pump.
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7885004
Pkg of 1, kit includes all fittings, for regular maintenance of the NGC F100 pump
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7885005
Pkg of 1, includes all fittings, seals, and check valves for servicing one F100 NGC Sample Pump
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7884019
Pkg of 1, 750 µl base and top assembly, included with all NGC 100 Systems
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7884028
Pkg of 1, 2 ml extension barrel for F100 750 µl mixer, part of NGC Scout™ 100, NGC Discover™ 100 Series
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7884023
Pkg of 1, 5 ml extension barrel for F100 750 µl mixer body, optional part
ngc-f100-mixer-barrel-large-12ml-788-4024-thumb-ngc-100-medium-pressure-chromatography-systems.jpg
7884024
Pkg of 1, 12 ml extension barrel for F100 750 µl mixer body, optional part
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(Discontinued) NGC™ Blank Module
7884005
Pkg of 1, blank module, for covering unused bays on the base and expansion layers
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(Discontinued) Computer
7884015
PC for ChromLab™ Software and database, communicates with and stores data generated by the NGC™ System
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(Discontinued) NGC™ Fittings Kit
7884017
Pkg of 1, kit includes multiple fittings, fittings maker, fittings tightener, ferrules, nuts, screwdrivers, pump head keys, and syringes required to set up, prepare, and prime NGC Systems

Documents

Documents

Number Description Options
7194
Integrating the CETAC MVX-7100 Autosampler with the NGC Chromatography System Protocol, Ver A
7031
Integrating the ALIAS Autosampler with the NGC™ Chromatography System Protocol
6286
NGC Chromatography Systems Brochure
[ Add to Cart (Free) ]
6326
NGC Chromatography Systems Module Selection Guide
[ Add to Cart (Free) ]
6778
Recommended Flow Rates for Tubing, UV/Vis Flow Cells, and Mixer Barrels on NGC™ Chromatography Systems Guide, Ver A
[ Add to Cart (Free) ]
7195
Integrating the CETAC MVX-7100 Autosampler with the NGC Chromatography System Quick Guide, Ver A