Overview
Nuvia cPrime weak cation exchange – hydrophobic interaction (CEX-HIC) mixed-mode media is designed for laboratory- and process-scale purification of a wide variety of therapeutic proteins. Nuvia cPrime media's unique selectivity allows method developers to use hydrophobic and cation exchange interaction modes to achieve effective purification. More importantly, the media have a large design space for binding and elution, allowing for the development of highly robust methods in a commercial manufacturing setting. Nuvia cPrime media are built on a rigid, mechanically and chemically stable macroporous base matrix with a particle size optimized to deliver exceptional flow properties, fast mass transfer, and stability.
Nuvia cPrime delivers value by providing:
- New and unique selectivity
- Salt tolerant media
- Simple method development
- Large design space for capture and elution of a variety of biotherapeutic proteins
- High recovery of target protein
- Mechanical and chemical stability
More Information
Specifications
Lactoferrin: >60 mg/ml
(20 cm × 20 cm packed bed; 1.17 comp. factor)
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25 ml, hydrophobic cation exchange chromatography media, 70 µm particle size
25 ml, hydrophobic cation exchange chromatography media, 70 µm particle size, shipped in 2% benzyl alcohol
100 ml, hydrophobic cation exchange chromatography media, 70 µm particle size
100 ml, hydrophobic cation exchange chromatography media, 70 µm particle size, , shipped in 2% benzyl alcohol
500 ml, hydrophobic cation exchange chromatography media, 70 µm particle size
500 ml, hydrophobic cation exchange chromatography media, 70 µm particle size, shipped in 2% benzyl alcohol
1 L, hydrophobic cation exchange chromatography media, 70 µm particle size, shipped in 2% benzyl alcohol
5 L, hydrophobic cation exchange chromatography media, 70 µm particle size
5 L, hydrophobic cation exchange chromatography media, 70 µm particle size, shipped in 2% benzyl alcohol
10 L, hydrophobic cation exchange chromatography media, 70 µm particle size
10 L, hydrophobic cation exchange chromatography media, 70 µm particle size, shipped in 2% benzyl alcohol
Pkg of 1, 1 ml, prepacked hydrophobic cation exchange column, 7 mm x 25 mm, max. pressure 45 psi, for use with NGC Systems or any chromatography system