Nuvia S Resin

Nuvia S Resin

Nuvia S is an ultra-high capacity, next-generation cation exchange resin built on the industry-proven UNOsphere™ base matrix technology. Nuvia S resin may be used in both the capture and polishing of biotherapeutics.

Read More
Ordering Information

Overview

Nuvia S Resin is an ultra-high capacity, next-generation cation exchange resin built on the industry proven UNOsphere™ base matrix technology. Nuvia S Resin provides very high capture and exceptional flow properties designed to meet current and future process needs. Nuvia S Resin is a flexible alternative that may be used both as a capture or polishing solution. The media delivers superior binding capacity over a wide operational window, making it the tool of choice for a wide range of downstream processes.

Nuvia S Resin delivers value and flexibility by allowing users to:

  • Use less media to purify a given amount of product
  • Reduce cycle time and increase productivity by operating at higher flow rates
  • Reduce costs and space requirements by decreasing buffer consumption
  • Reduce capital and operating expenses through the use of smaller columns
  • Chemical stability to withstand repetitive clean-in-place cycles
  • Flexibility in use for capture or polish steps
  • Fully supported for regulatory submission

More Information

Specifications

Type of ion exchanger
Strong cation
Functional group
–SO3
Total ionic capacity
90–150 µeq/ml
Dynamic binding capacity*: 300 cm/hr
≥110 mg/ml
Shipping counterion
Na+
Median particle size
85 ± 15 µm
Operational flow rate**
50–600 cm/hr
Chemical stability: 1.0 N NaOH (20ºC)
Up to 1 week
Chemical stability: 0.1 N NaOH (20ºC)***
Up to 5 years
Gel bed compression ratio
1.15–1.18 (settled bed volume/packed bed volume)
pH stability short-term***
2–14
pH stability long-term***
4–13
Shipping solution
All volumes are available in 20% ethanol + 0.1 M NaCl. Volumes of 500 ml or more are also available in 2% benzyl alcohol (BA).
Regeneration
1–2 M NaCl
Sanitation
0.5–1.0 N NaOH
Storage conditions
20% ethanol or 0.1 N NaOH
 
 
* 10% breakthrough capacity determined with 4.5 mg/ml human
IgG in 40 mM NaOAc + 30 mM NaCl, pH 5.0.
 
** Recommended elution flow rates are ≤ 150 cm/hr to minimize viscosity-induced backpressure.
 
*** Data derived under accelerated conditions at 60°C.
 

Ordering

items

Use the filters below to refine results!

Image
NuviaBottle05L
(Discontinued) Nuvia™ S
12018126

5 L, strong cation exchange chromatography media, 85 μm particle size

Image
foresight-unosphere-plate-family-thumb.jpg
7324701
2 x 96-well plates, 20 μl, filter plate prepacked with Nuvia S Strong Cation Exchange Chromatography Media
Image
foresight-robocolumn-unosphere-200ul-thumb.jpg
7324801
1 row of 8 columns, 200 μl, RoboColumn unit prepacked with Nuvia S Strong Cation Exchange Chromatography Media
Image
foresight-robocolumn-unosphere-600ul-thumb.jpg
7324802
1 row of 8 columns, 600 μl, RoboColumn unit prepacked with Nuvia S Strong Cation Exchange Chromatography Media
Image
EconoFit_Columns-1x1ml-Sku_TN.png
12009291

Pkg of 1, 1 ml, prepacked cation exchange column, 7 mm x 25 mm, max. pressure 45 psi, for use with NGC Systems or any chromatography system

Documents

Number Description
Add to Cart (Free)