Macro-Prep CM Resin

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Overview

Macro-Prep CM weak cation exchange support meets the demands of analytical, semipreparative, and process-scale applications.
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Description

Description

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Macro-Prep CM Resin is a weak cation exchange resin that meets the demands of analytical, semipreparative, and process-scale applications. This rigid, macroporous hydrophilic support provides exceptional capacity, resolution, and throughput in a chemically and mechanically stable form. Macro-Prep CM Resin operates well at low and medium pressures and exhibits minimal volume changes in response to variations in pH or ionic strength. It provides consistent and reproducible results.

Features and Benefits

  • High capacity for biomolecules
  • High resolution of complex biological mixtures
  • Rigid polymer matrix that allows high flow rates at moderate pressures
  • Hydrophilic matrix that reduces nonspecific binding
  • Macroporous beads that enhance access to ionic sites
  • Chemical, mechanical, and thermal stability

More Information

Instruction Manual, Macro-Prep Ion Exchange Resins (LIT271)

Specifications

Specifications

Type of ion exchanger
Weak cation
Counterion
Na+
Total ionic capacity
210±40 µeq/ml
Median particle
50 µm
Storage solution
20% ethanol
Recommended maximum linear flow rate
3,000 cm/hr
Chemical stability
 
   1% SDS, 24 hr
Yes
   6 M guanidine-HCl, 24 hr
Yes
   pH stability
1–12
Volume changes
 
   pH 4–10
<1%
   0.1–1.0 M NaCl
<4%
Regeneration
1 M NaCl
Autoclavability (121°C, 30 min)
Yes

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156-0072
5 L, weak cation exchange chromatography media, for analytical, semi-preparative, and process scale applications, 50 μm particle size
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156-0073
10 L, weak cation exchange chromatography media, for analytical, semi-preparative, and process scale applications, 50 μm particle size

Kits & Reagents

Kits & Reagents

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1250562
Pkg of 6 vials, lyophilized mixture of equine myoglobin, Ribonuclease A, cytochrome c, for use in ion exchange chromatography

Documents

Documents

Number Description Options
LIT271
Instruction Manual, Macro-Prep Ion Exchange Supports, Rev D
6983
Native and Recombinant Protein Purification Resins/Media Selection Card
6810
Practical Guide: Selecting the Optimal Resins for the Process Purification of Native and Recombinant Proteins, Ver A
5662
Process Chromatography Applications Laboratory Brochure, Rev B