Vericheck ddPCR Replication Competent AAV Kit #12019571



The Vericheck ddPCR Replication Competent AAV (RCAAV) kit provides a rapid, cost effective, sensitive, and fully validated solution for the detection of RCAAV.



Adeno-associated virus (AAV) is commonly used as a viral vector in cell and gene therapy production, but there is a risk of it becoming a replication competent virus (RCV) during the production process, especially in the presence of a helper virus, which can raise safety concerns. While the guidelines recommend a cell culture–based method for RCAAV testing, it is cumbersome and takes 30–45 days from sample to results. Vericheck ddPCR RCAAV Kit is a fast, cost-effective, specific, and fully validated solution for AAV testing.

Features and Benefits

  • Fast turnaround time: Results in as little as 8 hours
  • High sensitivity: LOD of 0.50 copies/µl for RCAAV
  • High specificity: 99.9%
  • Novel assay design: Kit validated to be serotype agnostic (AAV1-AAV10) and offers low CV (<10%) for reproducible results
  • Automated data analysis: Simplified workflow with positive controls included in the kit to aid automated results
  • Comprehensive ddPCR workflow: Supports and provides flexibility to run multiple samples per run

Product Contents

Description Catalog Quantity
ddPCR RCAAV Assay 16011505 1
ddPPCR RCAAV Positive Control 12019398 1
ddPCR RCAAV Internal Control 12019428 1
Nuclease-Free Water 8006877 1
Residual DNA Quantification Supermix 12017072 2

Configuration Options

(Bundles or different component sets) Catalog Number
QXONE Droplet Digital PCR System 12006536
QX200 AutoDG Droplet Digital PCR System consisting of:
QX200 Droplet Reader
Automated Droplet Generator
QX600 Droplet Digital PCR Reader 12013328
QX Manager Software, Regulatory Edition 12012172
QX Manager Software, Standard Edition 12012171
QX ONE Software, Regulatory Edition 12012078
QX Manager, Premium Edition 12018108

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Number Description Options
Vericheck ddPCR Replication Competent AAV Kit, User Guide