Affi-Gel Hz hydrazide gel activated support couples immunoglobulin G (IgG) molecules via carbohydrate moieties on the Fc region of antibody molecules. Fc attachment results in a more specific antigen-antibody interaction and 100–300% higher antigen binding capacity than that of other media.
Affi-Gel Hz support advantages include:
- Stable covalent hydrazone bonds
- Mild oxidation without alteration of antibody activity
- High antigen binding capacity
- pH stability
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