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|Genetic Screening||Viral DNA/RNA Quantification||Viral Protein Characterization||Viral Genomics||More R&D Solutions|
Characterizing the underlying virus, SARS-CoV-2, which causes COVID-19 infection is key to the development of effective diagnostic tools, vaccines, and therapeutics against the pathogen. Explore tools to support your research into understanding virus structure, infectivity, and viral load along with host-pathogen interaction and pathogen immune evasion strategies.
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Genetic Screening: Understanding Host Genetics
Genotype screening for host susceptibility, and exploring changes in gene expression during viral infection, are some of the key studies performed using PCR amplification of viral RNA and DNA. Bio-Rad offers the most advanced real-time PCR detection systems and PCR & qPCR reagents on the market.
Real-Time PCR Assay Panel for Coronavirus Disease Research
Study differential gene expression in response to coronavirus infection using our disease state qPCR assay panels.
- Bench-tested, guaranteed-to-perform assays
- Obtain gene expression profile of a whole pathway in one experiment
- Assay panels for human, mouse, and rat genes
PrimePCR PCR Primers, Assays, and Arrays
Experimentally validated PCR primer and probe assays for gene expression, copy number variation, and mutation detection analysis for real-time qPCR and Droplet Digital PCR. Alternatively, order custom oligonucleotides to design your own assays.
Find PCR Assays
Viral DNA/RNA Detection & Quantitation
Droplet Digital PCR Systems for Viral Titer, LD50, and ID50 Measurements
Precise and accurate viral quantification is critical to assess disease progression and virologic response to treatment, and for the determination of viral load, infectivity, and potency.
Droplet Digital PCR enables exquisitely precise, sensitive, and absolute nucleic acid quantification without a standard curve. Bio-Rad’s ddPCR systems enable measurement of low-abundance targets, targets in complex backgrounds, and subtle changes in target levels undetectable by real-time PCR, giving ddPCR Assays the ability to accurately quantitate even very low copy numbers.
Detect single-nucleotide variants and easily discriminate between closely related viral strains with high specificity and sensitivity.Browse ddPCR Systems
Find ddPCR Assays for applications including gene expression, mutation detection, CNV determination, and genome edit detection.
Digital PCR supermixes are validated to deliver maximum PCR efficiency and sensitivity for DNA and RNA targets on Droplet Digital PCR Systems.
Droplet generation oil, cartridges, gaskets, plates & seals, pipette tips, and more, specially designed for Droplet Digital PCR Systems.
Highly Precise Measurement of HIV DNA by Droplet Digital PCR Strain MC et al. PLoS One 2013;8(4):e55943
Browse the growing list of cited peer-reviewed journal articles in Droplet Digital PCR Research.
Viral Protein Characterization
Stain-Free Western Blotting: Identification & Quantitation of Viral and Host Proteins
Electrophoresis and blotting are preeminent tools for characterization of viral interactions with host proteins such as cell receptors mediating viral entry and replication. Our complete workflow solution for protein detection and quantitation features proprietary stain-free protein gels and imaging systems, which can provide data in as little as 30 minutes.
- Stain-free and fluorescent gel and blot imaging
- Validated primary western antibodies
- Fluorescent secondary western antibodies
Viral Genomics: Understanding Coronavirus Genetic Variation & Diversity
Droplet Digital PCR Assays are ideal for the detection of single-nucleotide variants (SNP) and can discriminate between closely related viral strains with high specificity and sensitivity.
ddPCR Mutation Detection Assays for Coronavirus Genetics Studies
- Detect mutant DNA at 0.1% of wild-type in one well — down to 0.005–0.1% with multiple wells
- Wet-lab validated assays available for more than 200 targets — guaranteed to work when used as instructed
- Validation data available for review and download
- Instant assay design for custom target sequences
Coinfection of Human Herpesviruses 6A (HHV-6A) and HHV-6B as Demonstrated by Novel Digital Droplet PCR Assay Leibovitch EC et al. PloS one vol. 9,3 e92328. 24 Mar. 2014
Characterization of Oseltamivir-Resistant Influenza Virus Populations in Immunosuppressed Patients Using Digital-Droplet PCR: Comparison With qPCR and Next Generation Sequencing Analysis Pichon M et al. Antiviral Res. 2017;145:160‐167