Helios® Gene Gun System

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Overview

The Helios gene gun is a convenient handheld device that provides direct, rapid, and versatile gene delivery into a range of targets in vivo.

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Description

Description

The Helios gene gun is a convenient handheld device that provides rapid and direct transfection into a range of targets in vivo. The unit uses an adjustable low-pressure helium pulse to sweep DNA-, RNA-, or biomaterial-coated gold microcarriers from the inner wall of a small plastic cartridge directly into target cells.

Key Features

  • Provides easy-to-use, rapid, versatile gene delivery independent of target cell type
  • Facilitates both transient and stable expression
  • Requires only small amounts of DNA and cells; no carrier DNA needed
  • Enables codelivery of more than one plasmid
  • Allows transfer of large DNA fragments
  • Targets intracellular gene delivery to many cells
  • Works for both in vitro and in vivo transformation
  • Delivers no extraneous genes or proteins

 

 

Helios® Gene Gun Training Video. This video provides an overview of the Helios Gene Gun Biolistic Particle Transfection System, including instrument setup, microcarrier and cartridge preparation, and instrument operation.

Ordering

Ordering

items

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165-2411_tn.jpg
(Discontinued) Helios Gene Gun Kit
1652411
100/120 V, handheld biolistic system, includes gene gun, 5 O-rings, 5 barrel liners, 5 white cartridge holders, cartridge extractor tool, 9 V battery.
165-2431_tn.jpg
1652431
100/120 V, handheld biolistic system, includes helium hose assembly with regulator, tubing prep station (#165-2418), syringe kit, Tefzel tubing, tubing cutter, optimization kit (#165-2424)
165-2451_tn.jpg
1652451
100/120 V, handheld biolistic system, includes helium hose assembly with low-pressure regulator, tubing prep station (#165-2418), syringe kit, tubing cutter, optimization kit (#165-2424)
165-2420_tn.jpg
(Discontinued) Tubing Prep Station
1652420
220/240 V, Helios gene gun sample preparation station, for the preparation of microparticle cartridges
165-2259_tn.jpg
(Discontinued) Voltage Converter
1652259
Pkg of 1, voltage converter, for use with PDS-1000/He system on 220–240 V lines

Accessories

Accessories

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1652244
Pkg of 12, positive control bullets, 1.6 μm gold particles coated with LacZ and luc; for use with the Helios gene gun system (#165-2431, #165-2432)
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(Discontinued) Helium Hose Assembly
1652412
Pkg of 1, Helios gene gun accessory, connects to helium source for safety and consistent helium delivery, with Swagelok quick-connect fittings
165-2413_tn.jpg
(Discontinued) Helium Regulator
1652413
Pkg of 1, pressure regulator for use with Helios gene gun, CGA 580 female fitting (U.S. standard) with pressure relief valve, max. pressure 2,600 psi
165-2414_tn.jpg
1652414
Pkg of 1, pressure regulator for use with Helios gene gun, CGA 580 female fitting (U.S. standard) with pressure relief valve, max. pressure 400 psi
165-2418_tn.jpg
(Discontinued) Tubing Prep Station
1652418
100/120 V, Helios gene gun sample preparation station, for the preparation of microparticle cartridges
165-2420_tn.jpg
(Discontinued) Tubing Prep Station
1652420
220/240 V, Helios gene gun sample preparation station, for the preparation of microparticle cartridges
165-2421_tn.jpg
(Discontinued) Syringe Kit
1652421
Kit for loading gold suspension into Tefzel tubing, includes syringe adaptor tubing, 5 x 10 ml syringes, syringe adaptor fitting, 5 Luer-Lok fittings
165-2422_tn.jpg
(Discontinued) Tubing Cutter
1652422
Pkg of 1, instrument for cutting Tefzel tubing, for use with the Helios gene gun, includes 10 razor blades
165-2424_tn.jpg
1652424
Optimization kit for the Helios gene gun, includes 0.6 μm, 1.0 μm and 1.6 μm gold microcarriers, PVP, desiccant, 5 cartridge storage vials, 50 feet of Tefzel tubing, for 1,000 samples
165-2440_tn.jpg
(Discontinued) Cartridge Kit
1652440
Kit for preparing Helios gene gun cartridges, includes 0.5 g PVP, 5 desiccant pellets, 5 cartridge collection/storage vials, 15 m of Tefzel tubing
165-2262_tn.jpg
1652262
0.25 g, 0.6 μm diameter, gold microcarriers for use with the PDS-1000/He and Helios gene gun systems
165-2263_tn.jpg
1652263
0.25 g, 1.0 μm diameter, gold microcarriers for use with the PDS-1000/He and Helios gene gun systems
165-2264_tn.jpg
1652264
0.25 g, 1.6 μm diameter, gold microcarriers for use with the PDS-1000/He and Helios gene gun systems
165-2425_tn.jpg
1652425
Pkg of 1, nitrogen regulator, for drying Tefzel tubing during Helios gene gun sample preparation
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(Discontinued) O-Rings
1652416
Pkg of 5, O-rings for use with the Helios gene gun system (#165-2431, #165-2432)
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(Discontinued) Barrel Liner
1652417
Pkg of 5, sample preparation accessory for Helios gene gun
165-2426_tn.jpg
(Discontinued) Cartridge Holder
1652426
Pkg of 5, accessory for loading microparticle-coated cartridges into the Helios gene gun, white
165-2435_tn.jpg
1652435
Pkg of 1, tool for removing discharged cartridges, for use with the Helios gene gun (#165-2431, #165-2432)
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(Discontinued) Battery
1652436
Pkg of 1, 9 V alkaline battery, for use with the Helios gene gun, provides 1,000 discharges in continuous use
165-2441_tn.jpg
(Discontinued) Tefzel Tubing
1652441
15 m, tubing for coating with DNA- or RNA-gold microcarrier complexes, used with the Helios® gene gun, .125" (3.175 mm) OD, .093" (2.36 mm) ID
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1652475
Pkg of 5, screens for use with the Helios gene gun (#165-2431, #165-2432)

Microcarriers

Microcarriers

165-2262_tn.jpg
1652262
0.25 g, 0.6 μm diameter, gold microcarriers for use with the PDS-1000/He and Helios gene gun systems
165-2263_tn.jpg
1652263
0.25 g, 1.0 μm diameter, gold microcarriers for use with the PDS-1000/He and Helios gene gun systems
165-2264_tn.jpg
1652264
0.25 g, 1.6 μm diameter, gold microcarriers for use with the PDS-1000/He and Helios gene gun systems

Documents

Documents

Number Description Options
5443
Biolistic Particle Delivery Systems Brochure, Rev A
5446
Helios Gene Gun System Flier, Rev A
10000118158
Instruction Manual, Helios Gene Gun System
10000148591
Update to EN 61010-1 Amendment Statement of Operating Conditions
4106137
Instruction Manual, GeneShot Control Cartridges
M1652475
Instruction Manual, Helios® Gene Gun Diffusion Screen, Rev A
2552
The Gene Gun: Current Applications in Cutaneous Gene Therapy, Rev A
2433
Transformation of Nematodes With the Helios Gene Gun
2453
Optimization of Gene Delivery Into Arabidopsis, Tobacco, and Birch Using the Helios Gene Gun System
2531
Inoculation of Viral RNA and cDNA to Potato and Tobacco Plants Using the Helios Gene Gun
2726
Delivery of pCMV-S DNA Using the Helios® Gene Gun System Is Superior to Intramuscular Injection in Balb/c Mice
1689
Comparison of Performance Characteristics of Different Biolistic® Devices
2768
Biolistic Gene Transfer to Generate Transgenic Schistosomes, Rev A
2410
Detection of Reporter Gene Activity in Cell Cultures and Murine Epidermis After Helios® Gene Gun-Mediated Particle Bombardment, Rev B