QXDx AutoDG ddPCR System

The QXDx AutoDG ddPCR System is Bio-Rad's Droplet Digital PCR system that is FDA-cleared for use with QXDx BCR-ABL %IS Kit monitoring in the clinical lab. The same system, which includes the QXDx Automated Droplet Generator and QXDx Droplet Reader, provides precise and absolute quantification of target DNA and RNA molecules in a wide variety of research applications.

Features and Benefits

• FDA-Cleared — the first FDA-cleared ddPCR system giving the industry a quality product with great sensitivity and reproducibility
• CE marking — quality product with great sensitivity and reproducibility
• Absolute quantification — provides an absolute count of target DNA copies per input without the need for standard curves
• Highest precision and sensitivity — enriched template concentration in target-positive droplets enabling higher precision and sensitivity than quantitative PCR (qPCR)
• High throughput — simple and easy-to-use workflow with 96-reaction throughput
• Removal of PCR efficiency bias — error rates are reduced by removing the reliance on amplification efficiency of qPCR due to high tolerance of PCR inhibitors
• Automated droplet generator — simplifies the ddPCR workflow and offers flexibility

Research Applications and Uses

Included Components

• QXDx Automated Droplet Generator
• QXDx Droplet Reader
• QXDx Acquisition and Analysis Software
• QXDx Dual Partitioned Laptop
• QuantaSoft Software

Related Products

• QXDx Universal Kit for AutoDG ddPCR System (17001378)
• QXDx AutoDG Supermix Pack (12003031)
• QXDx AutoDG Consumable Pack (12001922)
• QXDx Droplet Reader Oil Pack (12002526)
• QXDx ddPCR System

The QXDx AutoDG ddPCR System is used and validated with the following thermal cycler specifications:

• Accuracy: ±0.2°C
• Uniformity: ±0.4°C well-to-well within 10 sec
• Adjustable ramp capability with required ramp rate: up to 2°C/sec
• Temperature range: 0–100°C

The C1000 Touch Thermal Cycler with 96–Deep Well Reaction Module (1851197) was used during the development and validation efforts of all QXDx products.

Related Categories

Digital PCR