Description
Description
Bio-Plex SARS-CoV-2 Neutralization Antibody Assays Webinar
Bio-Plex Pro Human SARS-CoV-2 Neutralization Antibody Assays* allow researchers to assess the efficacy of COVID-19 vaccines or compare the effectiveness of naturally acquired or vaccine-induced antibody response to arising variants of concern. The highly precise and specific assays are offered as an 11-Plex 96-well plate complete kit that includes Wild-type S1, Wild-type RBD, Alpha Spike 1, Beta Spike 1, Gamma RBD, Epsilon RBD, Kappa RBD, D614G Spike 1, E484K RBD, K417N RBD, and N501 RBD. The wild-type S1 and RBD are also available as a 2-plex 96-well plate kit. SARS-CoV-2 antigens are coated on magnetic beads that bind neutralizing antibodies in competition with a biotinylated detection ACE2 receptor.
*Bio-Plex Pro SARS-CoV-2 Neutralization Antibody Assays are for research use only.
Features and Benefits
- Comprehensive panel coverage — detects neutralizing antibody response to two wild-type and 11 SARS-CoV-2 variants
- Fast protocol — results in less than 3 hours
- High precision and specificity — for greater confidence in measuring SARS-CoV-2 specific antibodies in serum and plasma samples
- Reproducibility — attain consistent results in your experiments with a robust magnetic bead-based workflow
Ordering Options for Bio-Plex Neutralization Antibody Assays
- Select complete kits for multiplex target panels
- Create multiplex assays with singleplex SARS-CoV-2 neutralization variant antigen coupled beads
- Develop your own variant assay with Bio-Plex Pro Human SARS-CoV-2 Neutralization Antibody Custom Assay Developer Kit
How to Order Individual Bio-Plex SARS-CoV-2 Neutralization Antibody Assay Components
Human samples require four components for a complete assay:
- Bio-Plex Pro SARS-CoV-2 wild-type or variant* antigen coupled beads
- Bio-Plex Pro SARS-CoV-2 Neutralization Antibody Reagent Kit (12017037)
- Bio-Plex Pro SARS-CoV-2 Neutralization Antibody Standard (12016945)
- Bio-Plex Pro Biotinylated Detection ACE2 Receptor (12016944)
*Researchers must provide their own variant antigen coupled beads.
For samples from other species, researchers must provide their own positive control, and standard. The appropriate species-specific reagent kit should also be used.
- Bio-Plex Pro Reagent Kit V with Flat Bottom Plate, 1 x 96-well (12002798)
Related Products
- SARS-CoV-2 Antibody Profiling: Measure antibodies against SARS-CoV-2 Nucleocapsid, RBD, Spike 1, Spike 2 viral antigens
- Cytokine Profiling: Characterize the Effects of SARS-CoV-2 Infection
Related Categories
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1 x 96-well, includes SARS-CoV-2 wild-type and variant coupled magnetic capture beads, biotinylated detection ACE2 receptor, standard, ready-to-use positive control, assay buffer, wash buffer, serology sample diluent, streptavidin-phycoerythrin (SA-PE), 96-well flat bottom plate, and sealing tape. For the detection of human neutralization antibodies against SARS-CoV-2 RBD, S1, Alpha S1, Beta S1, Gamma RBD, D614G S1, E484K RBD, Epsilon RBD, K417N RBD, Kappa RBD, N501Y RBD antigens.
1 x 96-well, includes SARS-CoV-2 wild-type Receptor Binding Domain (RBD) and Spike 1 (S1) coupled magnetic beads, biotinylated detection ACE2 receptor, standard, ready-to-use positive control, assay buffer, wash buffer, serology sample diluent, streptavidin-phycoerythrin (SA-PE), flat bottom plate, and sealing tape. For the detection of human neutralization antibodies against SARS-CoV-2 wild-type RBD and Spike 1 antigens.
Kits & Reagents
Kits & Reagents
1 x 96 well, assay buffer, wash buffer, serology sample diluent, streptavidin-PE, flat-bottom plate, and sealing tape. To be used with Bio-Plex Pro SARS-COV-2 Antigen Coupled beads, Bio-Plex Pro Neutralization Antibody Standard, and Bio-Plex Pro Biotinylated Detection ACE2 Receptor.
1 x 96-well, biotinylated detection ACE2 receptor. The SARS-CoV-2 spike protein binds to the ACE2 receptor during viral entry. Requires Bio-Plex Pro Neutralization Reagent Kit, Bio-Plex Pro Neutralization Antibody Standard, and Bio-Plex Pro SARS-CoV-2 Antigen Coupled Beads to run a complete singleplex or multiplex assay.
Pkg of 1 vial, Neutralization Antibody Standard binds to SARS-CoV-2 viral antigens, enough to generate a standard curve in duplicate for 1 x 96 well plate; for use with Bio-Plex Pro SARS-CoV-2 Antigen Coupled Beads, Bio-Plex Pro Biotinylated Detection ACE2 Receptor, Bio-Plex Pro SARS-CoV-2 Neutralization Antibody Reagent Kit.
Assay Developer Kit
Assay Developer Kit
SARS-CoV-2 Neutralization Antibody Custom Assay Developer Kit. Includes Bio-Plex Pro Human SARS-COV-2 Neutralization Antibody 2-Plex Panel Kit, Bio-Plex Amine Coupling Kit for coupling proteins to magnetic beads (bead wash and activation buffers, storage and staining buffers, tubes), Bio-Plex Pro Magnetic COOH Beads 27, and Bio-Plex Pro Serology Beads Storage Buffer.
Coupled Beads
Coupled Beads
Pkg of 1, SARS-CoV-2 RBD viral protein coupled magnetic beads, for capturing anti-SARS-CoV-2 antibodies specific for RBD from multispecies serum or plasma, sufficient for 96 reactions; Requires isotype-specific detection antibody, reagent kit, and isotype-specific control set.
Pkg of 1, SARS-CoV-2 S1 viral protein coupled magnetic beads, for capturing anti-SARS-CoV-2 antibodies specific for Spike 1 from multispecies serum or plasma, sufficient for 96 reactions; Requires isotype-specific detection antibody, reagent kit, and isotype-specific control set.