Vericheck QX700™ ddPCR Replication Competent Lentivirus Kit #12025890

Replication competent lentivirus (RCL) testing is a critical quality control step in lentiviral vector manufacturing for cell and gene therapy applications. The Vericheck QX700 ddPCR Replication Competent Lentivirus Kit is a Droplet Digital PCR–based solution designed for rapid, sensitive, and specific detection of viral replication genes that may indicate the presence of RCL. By combining absolute quantification with a streamlined workflow and automated data analysis, the kit helps reduce turnaround time compared with traditional cell culture–based methods while supporting efficient in-house testing on the QX700 ddPCR System.*

Features & Benefits

Fast turnaround time

• Delivers results in as little as 8 hours, enabling faster decision-making than traditional cell culture–based RCL testing workflows

High sensitivity and specific detection

• Provides sensitive detection of replication competent lentivirus with a limit of detection of 0.35 copies/b5L, supporting low-level measurements in manufacturing samples
• Detects viral replication genes with high specificity, helping identify potential RCL events during lentiviral vector production

Validated, reproducible workflow

• Fully validated kit includes positive and internal controls to support simplified setup, automated data analysis, and consistent interpretation of results
• Delivers reproducible performance with low variability across lots, users, plates, and instruments, supporting robust QC workflows
• Flexible ddPCR workflow supports multiple samples per run on the QX700 System, improving in-house testing efficiency

Applications & Uses

• Perform in-house testing for replication competent lentivirus during lentiviral vector manufacturing
• Monitor manufacturing samples for viral replication genes that may indicate potential RCL formation
• Support quality control, process development, and safety testing throughout manufacturing and production

*For Research Use Only. Not for use in diagnostic procedures.

Equipment

This kit requires the use of one of the following instruments:

• QX700™ E Droplet Digital PCR System
• QX700™ S Droplet Digital PCR System
• QX700™HT Droplet Digital PCR System