UNO® Monolith Ion Exchange Columns

UNO monolith ion exchange columns contain a patented* continuous-bed matrix allowing biomolecule separations at high flow rates without sacrificing resolution or capacity. In continuous-bed technology, advanced monomers and ionomers are polymerized directly in the column and aggregate into a dense homogeneous network of nodules. The resulting rigid matrix contains interconnecting channels large enough to allow fast hydrodynamic flow at low backpressures. The continuous-bed matrix yields a column with exceptional resolution, speed, capacity, and value for the separation of biomolecules. The homogeneous, nonporous continuous-bed matrix allows extremely fast mass transfer of proteins and eluent to the ionic functional groups.

UNO Q columns are for strong anion exchange, while UNO S columns are for strong cation exchange. Choose from the following UNO columns:

• UNO glass columns provide high-resolution separation of biomolecules. The transparent glass tube allows easy bed inspection and column troubleshooting
• UNO replacement columns provide a simple bed replacement as an alternative to purchasing a new column
• UNO polishing PEEK columns provide a late-stage purification tool used to obtain the highest resolution and recovery from small sample loads. The column allows you to purify and concentrate dilute samples in one step

* U.S. patent 6,423,666.