
Description
Description
Bio-Plex Pro Human SARS-CoV-2 Neutralization Antibody Assays* allow researchers to assess the efficacy of COVID-19 vaccines or compare the effectiveness of naturally acquired or vaccine-induced antibody response to arising variants of concern. The highly precise and specific assays are offered as an 11-Plex 96-well plate complete kit that includes Wild-type S1, Wild-type RBD, Alpha Spike 1, Beta Spike 1, Gamma RBD, Epsilon RBD, Kappa RBD, D614G Spike 1, E484K RBD, K417N RBD, and N501 RBD. The wild-type S1 and RBD are also available as a 2-plex 96-well plate kit. SARS-CoV-2 antigens are coated on magnetic beads that bind neutralizing antibodies in competition with a biotinylated detection ACE2 receptor.
*Bio-Plex Pro SARS-CoV-2 Neutralization Antibody Assays are for research use only.
Features and Benefits
- Comprehensive panel coverage — detects neutralizing antibody response to two wild-type and 11 SARS-CoV-2 variants
- Fast protocol — results in less than 3 hours
- High precision and specificity — for greater confidence in measuring SARS-CoV-2 specific antibodies in serum and plasma samples
- Reproducibility — attain consistent results in your experiments with a robust magnetic bead-based workflow
Ordering Options for Bio-Plex Neutralization Antibody Assays
- Select complete kits for multiplex target panels
- Create multiplex assays with singleplex SARS-CoV-2 neutralization variant antigen coupled beads
- Develop your own variant assay with Bio-Plex Pro Human SARS-CoV-2 Neutralization Antibody Custom Assay Developer Kit
How to Order Individual Bio-Plex SARS-CoV-2 Neutralization Antibody Assay Components
Human samples require four components for a complete assay:
- Bio-Plex Pro SARS-CoV-2 wild-type or variant* antigen coupled beads
- Bio-Plex Pro SARS-CoV-2 Neutralization Antibody Reagent Kit (12017037)
- Bio-Plex Pro SARS-CoV-2 Neutralization Antibody Standard (12016945)
- Bio-Plex Pro Biotinylated Detection ACE2 Receptor (12016944)
*Researchers must provide their own variant antigen coupled beads.
For samples from other species, researchers must provide their own positive control, and standard. The appropriate species-specific reagent kit should also be used.
- Bio-Plex Pro Reagent Kit V with Flat Bottom Plate, 1 x 96-well (12002798)
Related Products
- SARS-CoV-2 Antibody Profiling: Measure antibodies against SARS-CoV-2 Nucleocapsid, RBD, Spike 1, Spike 2 viral antigens
- Cytokine Profiling: Characterize the Effects of SARS-CoV-2 Infection