Hemoglobinopathy Educational Program
Are you looking for tools to help you evaluate unusual chromatograms? You may encounter hemoglobin variant cases that require expertise to understand. Bio-Rad is here to help. To complement our world class hemoglobin testing systems, we offer educational support to help you serve the clinicians and patients who count on you.
Check out our Test Your Knowledge series of educational case studies. Each case study is designed to help you build and grow your knowledge and understanding of chromatograms.
HbA1c Case Studies
To help you understand different hemoglobin A1c testing methods and how hemoglobinopathies affect HbA1c results, we've created numerous case studies. Click on each video to learn and test your knowledge.
Homozygous/Double Heterozygous
Marco Flamini reviews homozygous and double
heterozygous hemoglobinopathies and their effects on HbA1c results.
HbF
Marco Flamini reviews cases of elevated HbF and the
impact it has on various HbA1c testing methods.
A New Perspective on HbA1c Evaluation
A holistic overview of hemoglobinopathies interactions with glycated hemoglobin
By M. Flamini, MSc as seen in the Medical Laboratory Observer
Knowledge and awareness of thalassemia and hemoglobin variants affecting HbA1c measurements is essential. In this article, Marco Flamini emphasizes the need to evaluate hemoglobin variants that are coinherited with thalassemia and/or associated with elevated HbF. Ultimately, identifying the clinical status of the patient will lead to accurate result interpretation and better patient treatment decisions.
Hemoglobinopathy Case Studies
To help you better evaluate thalassemia, sickle cell, and hemoglobin variant cases, we've selected case studies from the Library of Variants for discussion. Click on each video to learn and test your knowledge.
Thalassemia Case 1
Marco Flamini reviews one of the most typical chromatograms found in a hemoglobinopathy lab.
Thalassemia Case 2
Marco Flamini presents an unusual chromatogram and the steps for how to evaluate it.
Sickle Cell
Marco Flamini reviews one of the most typical chromatograms found in a hemoglobinopathy lab.
Hemoglobin Variants
Marco Flamini reviews a chromatogram showing an unknown peak just after HbA2.
Webinar: Evaluation of Hemoglobinopathies by HPLC
For more details on how to evaluate hemoglobinopathies by HPLC, view our webinar.
List of Hemoglobin Variants
Patient care is at the heart of what you do. We're here to help you serve clinicians and their patients. There are thousands of rare hemoglobin variants that could appear on your chromatograms. And since we know how important it is to identify unknown peaks and accurately analyze chromatograms, we've developed a list of hemoglobin variants that were run on the VARIANT II Beta Thalassemia Short Program.
This convenient list, organized by retention time, can be used as an educational tool to help when you are evaluating unfamiliar hemoglobin variant cases and considering further studies.
Expertise and Education
Library of Variants Demo Video
View our step-by-step video on how the Library of Variants tool can help you evaluate your chromatograms.
Library of Variants (LoV)
Educational database of shared HPLC cases from around the world.
Hemoglobin Testing Solutions
D-10 System
Fully automated, compact HPLC system for HbA1c and β-thalassemia testing
For small volume laboratories
Hemoglobinopathy Testing Systems
Fully automated HPLC for β-thalassemia and sickle cell testing
For small, medium, and large laboratories
Other Resource Tools to Guide Evaluations
We have developed several posters featuring common phenotypes that you can download, print, and hang in your laboratory to use as a quick reference. There are five different posters organized by the program you run and the region in which you operate..
Data collected from running the VARIANT II Beta-Thalassemia Short Program:
Bio-Rad World of Hemoglobinopathies Map
Bio-Rad World of Hemoglobinopathies Map: Common Mediterranean Phenotypes
Bio-Rad World of Hemoglobinopathies Map: Common Southeast Asian Phenotypes
Data collected from running the D-10 Dual Program:
Bio-Rad World of Hemoglobinopathies Map: Common Phenotypes Run on the D-10 Dual Program in a French Laboratory (English)
Bio-Rad World of Hemoglobinopathies Map: Common Phenotypes Run on the D-10 Dual Program in a French Laboratory (French)