What to Look for in Newborn HPLC Chromatograms
In this training video, learn how to confidently evaluate high-performance liquid chromatography (HPLC) chromatograms in newborn screening. The session covers essential hemoglobin genetics, principles of chromatographic separation, and step-by-step guidance to interpret typical (FA) and atypical patterns. Gain practical insights to identify key peaks, recognize potential hemoglobinopathies, and apply a systematic approach for accurate, reliable results.
Learn to evaluate newborn HPLC chromatograms for hemoglobinopathy testing in this training webinar.
Key Takeaways:
- Identify the characteristics of a typical FA pattern in newborns
- Understand how hemoglobin genetics influence chromatogram results
- Recognize variant patterns and atypical findings
- Spot key flags, including minor peaks, low HbA, and transfusion indicators
- Apply a systematic approach to chromatogram review
Speaker
Marco Flamini
Senior Global Product Manager
Bio-Rad Laboratories
Marco Flamini has over 30 years of experience in hemoglobinopathy testing and holds a Master of Science in pharmacy, with an academic thesis in HPLC from the University of Rome. Marco played a key role in introducing automation with HPLC in national hemoglobinopathy screening programs, first in Mediterranean countries, then expanding globally, supporting national programs across various countries, participating in key studies and committees, and engaging in global educational initiatives on hemoglobinopathies and diabetes testing.
