Foresight Pro Chromatography Columns, CHT Ceramic Hydroxyapatite
Foresight Pro CHT prepacked columns are GMP ready and specifically designed to be used for all biopharmaceutical purification workflows. This includes a wide variety of purification and polishing applications for vaccines, monoclonal antibodies, and recombinant proteins.
Overview
Foresight Pro Chromatography Columns are good manufacturing practice (GMP) ready columns specifically designed to be used for all biopharmaceutical manufacturing applications. The columns have a sanitary design with minimal dead space and effective cleanability, and connections to pumping systems are made via standard 3/4" Tri-Clamp Fittings. CHT prepacked columns are available in a range of column diameters and bed heights. CHT prepacked columns are shipped in 0.1 N NaOH.
Features and Benefits
- GMP ready columns — validated and ready to use
- Excellent performance — data include asymmetry, HETP, endotoxin, and bioburden
- Robust column design ensures quality packing
- Columns maintain performance criteria after shipping and cycling
- Validated through ISTA 2A transportation testing
- All wetted parts meet USP Class VI requirements of USP <88>
- Standard Tri-Clamp connections — plug and play
- Columns are packed in a controlled ISO Class 7 cleanroom
- Range of column diameters and bed heights — 5–33 cm ID and 10 or 20 cm bed height
- Resin reference sample included with each column
- Regulatory support file available
Packing Quality
Figure 1: Evaluation of N/m, comparing pre- and post-ISTA 2A tests. Pre-ISTA 2A (
); Post-ISTA 2A()
Figure 2: Evaluation of As, comparing pre- and post-ISTA 2A tests. Pre-ISTA 2A (
); Post-ISTA 2A()
Cycling Data
Figure 1: Evaluation of N/m, comparing the first and tenth cycle of three Foresight Pro Columns.
First cycle (); Tenth cycle ()
Figure 2: Evaluation of As, comparing the first and tenth cycle of three Foresight Pro Columns.
Pre-ISTA 2A (); Post-ISTA 2A()
Non-Product Contact Material Summary
| Element | Material |
|---|---|
| Top and bottom supporting plates | Polypropylene |
| Holding bars | Polyamide or 304 stainless steel |
Product Contact Material Summary
| Element | Material | USP <88> Class | CFR 21 177 | Animal Origin |
|---|---|---|---|---|
| Column body | Glass (5 cm ID columns) | N/A | N/A | N/A |
| Column body |
Acrylic (8, 10, 13, 20, 24, 33 cm ID columns) |
Class VI | 177.1010 | Animal-free |
| Flow distributors | Polypropylene | Class VI | 177.1520 | Animal-free |
| Inlet and outlet connectors | Polypropylene | Class VI | 177.1520 | Animal-free |
| Tubing connections | Reinforced elastomer tubing | Class VI | 177.2600 | Animal-free |
| O-rings | Viton | Class VI | 177.2600 | Animal-free |
| Tri-clamp gasket | Ethylene propylene diene monomer (EPDM) | Class VI | 177.2600 | Animal-free |
| Bed support screens | Polyamide
Note: The polyamide bed support screen is welded |
Class VI | 177.1500 | Animal-free |
Related Products
- CHT Ceramic Hydroxyapatite Type I Media
- CHT Ceramic Hydroxyapatite Type II Media
- CHT Ceramic Hydroxyapatite XT Media
Related Categories
Specifications
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Foresight Pro Chromatography Column, 0.2 L CHT Ceramic Hydroxyapatite, Type I, 40 µm, 5 cm (diameter) x 10 cm (length)
Foresight Pro Chromatography Column, 0.4 L CHT Ceramic Hydroxyapatite, Type I, 40 µm, 5 cm (diameter) x 20 cm (length)
Foresight Pro Chromatography Column, 0.5 L CHT Ceramic Hydroxyapatite, Type I, 40 µm, 8 cm (diameter) x 10 cm (length)
Foresight Pro Chromatography Column, 1.0 L CHT Ceramic Hydroxyapatite, Type I, 40 µm, 8 cm (diameter) x 20 cm (length)
Foresight Pro Chromatography Column, 0.8 L CHT Ceramic Hydroxyapatite, Type I, 40 µm, 10 cm (diameter) x 10 cm (length)
Foresight Pro Chromatography Column, 1.5 L CHT Ceramic Hydroxyapatite, Type I, 40 µm, 10 cm (diameter) x 20 cm (length)
Foresight Pro Chromatography Column, 1.3 L CHT Ceramic Hydroxyapatite, Type I, 40 µm, 13 cm (diameter) x 10 cm (length)
Foresight Pro Chromatography Column, 2.7 L CHT Ceramic Hydroxyapatite, Type I, 40 µm, 13 cm (diameter) x 20 cm (length)
Foresight Pro Chromatography Column, 3.1 L CHT Ceramic Hydroxyapatite, Type I, 40 µm, 20 cm (diameter) x 10 cm (length)
Foresight Pro Chromatography Column, 6.3 L CHT Ceramic Hydroxyapatite, Type I, 40 µm, 20 cm (diameter) x 20 cm (length)
Foresight Pro Chromatography Column, 4.5 L CHT Ceramic Hydroxyapatite, Type I, 40 µm, 24 cm (diameter) x 10 cm (length)
Foresight Pro Chromatography Column, 9.0 L CHT Ceramic Hydroxyapatite, Type I, 40 µm, 24 cm (diameter) x 20 cm (length)
Foresight Pro Chromatography Column, 8.5 L CHT Ceramic Hydroxyapatite, Type I, 40 µm, 33 cm (diameter) x 10 cm (length)
Foresight Pro Chromatography Column, 17 L, CHT Ceramic Hydroxyapatite, Type I, 40 µm, 33 cm (diameter) x 20 cm (length)
Foresight Pro Chromatography Column, 0.2 L CHT Ceramic Hydroxyapatite, Type II, 40 µm, 5 cm (diameter) x 10 cm (length)
Foresight Pro Chromatography Column, 0.4 L CHT Ceramic Hydroxyapatite, Type II, 40 µm, 5 cm (diameter) x 20 cm (length)
Foresight Pro Chromatography Column, 0.5 L CHT Ceramic Hydroxyapatite, Type II, 40 µm, 8 cm (diameter) x 10 cm (length)
Foresight Pro Chromatography Column, 1.0 L CHT Ceramic Hydroxyapatite, Type II, 40 µm, 8 cm (diameter) x 20 cm (length)
Foresight Pro Chromatography Column, 0.8 L CHT Ceramic Hydroxyapatite, Type II, 40 µm, 10 cm (diameter) x 10 cm (length)
Foresight Pro Chromatography Column, 1.5 L CHT Ceramic Hydroxyapatite, Type II, 40 µm, 10 cm (diameter) x 20 cm (length)
Foresight Pro Chromatography Column, 1.3 L CHT Ceramic Hydroxyapatite, Type II, 40 µm, 13 cm (diameter) x 10 cm (length)
Foresight Pro Column, 2.7 L CHT Ceramic Hydroxyapatite, Type II, 40 µm, 13 cm (diameter) x 20 cm (length)
Foresight Pro Chromatography Column, 3.1 L CHT Ceramic Hydroxyapatite, Type II, 40 µm, 20 cm (diameter) x 10 cm (length)
Foresight Pro Chromatography Column, 6.3 L CHT Ceramic Hydroxyapatite, Type II, 40 µm, 20 cm (diameter) x 20 cm (length)
Foresight Pro Chromatography Column, 4.5 L CHT Ceramic Hydroxyapatite, Type II, 40 µm, 24 cm (diameter) x 10 cm (length)
Foresight Pro Chromatography Column, 9.0 L CHT Ceramic Hydroxyapatite, Type II, 40 µm, 24 cm (diameter) x 20 cm (length)
Foresight Pro Chromatography Column, 8.5 L CHT Ceramic Hydroxyapatite, Type II, 40 µm, 33 cm (diameter) x 10 cm (length)
Foresight Pro Chromatography Column, 17 L CHT Ceramic Hydroxyapatite, Type II, 40 µm, 33 cm (diameter) x 20 cm (length)
Foresight Pro Chromatography Column, 0.2 L CHT Ceramic Hydroxyapatite XT, 40 µm, 5 cm (diameter) x 10 cm (length)
Foresight Pro Chromatography Column, 0.4 L CHT Ceramic Hydroxyapatite XT 40 µm, 5 cm (diameter) x 20 cm (length)
Foresight Pro Chromatography Column, 0.5 L CHT Ceramic Hydroxyapatite XT 40 µm, 8 cm (diameter) x 10 cm (length)
Foresight Pro Chromatography Column, 1.0 L CHT Ceramic Hydroxyapatite XT, 40 µm, 8 cm (diameter) x 20 cm (length)
Foresight Pro Chromatography Column, 0.8 L CHT Ceramic Hydroxyapatite XT 40 µm, 10 cm (diameter) x 10 cm (length)
Foresight Pro Chromatography Column, 1.5 L CHT Ceramic Hydroxyapatite XT, 40 µm, 10 cm (diameter) x 20 cm (length)
Foresight Pro Chromatography Column, 1.3 L CHT Ceramic Hydroxyapatite XT, 40 µm, 13 cm (diameter) x 10 cm (length)
Foresight Pro Chromatography Column, 2.7 L CHT Ceramic Hydroxyapatite XT, 40 µm, 13 cm (diameter) x 20 cm (length)
Foresight Pro Chromatography Column, 3.1 L CHT Ceramic Hydroxyapatite XT, 40 µm, 20 cm (diameter) x 10 cm (length)
Foresight Pro Chromatography Column, 6.3 L CHT Ceramic Hydroxyapatite XT, 40 µm, 20 cm (diameter) x 20 cm (length)
Foresight Pro Chromatography Column, 4.5 L CHT Ceramic Hydroxyapatite XT, 40 µm, 24 cm (diameter) x 10 cm (length)
Foresight Pro Chromatography Column, 9.0 L CHT Ceramic Hydroxyapatite XT, 40 µm, 24 cm (diameter) x 20 cm (length)
Foresight Pro Chromatography Column, 8.5 L CHT Ceramic Hydroxyapatite XT, 40 µm, 33 cm (diameter) x 10 cm (length)
Foresight Pro Chromatography Column, 17 L CHT Ceramic Hydroxyapatite XT, 40 µm, 33 cm (diameter) x 20 cm (length)