Article Download
How to Use DOE to Select Resins for Antibody Purification
Screening resins for monoclonal antibody (mAb) purification is complicated both by the number of resins available and the myriad variables that must be considered to optimize a purification workflow. Using a systematic screening approach, such as design of experiments (DOE), can simplify resin selection by enabling a comprehensive evaluation of multiple input factors and their effects on desired outputs.
Read this article to learn more about:
- The limitations of a templated approach
- How to optimize chromatographic separations using DOE
- DOE case studies that cover a range of separation challenges and tips for optimization
Download the Article
Share a little information with us to access the entire article now.
Content you'll also find interesting
Recommended Features
-
Image
Optimizing mAb Purity and Recovery with Mixed-Mode Resins
Discover how mixed-mode approaches can streamline your purification workflow, increase efficiency and recovery of antibodies.
-
Image
Biosimilar Production with IEX and Mixed-Mode Resins
Learn how process economics is improved more than fourfold for biosimilar production with an ion exchange and mixed-mode purification workflow.
-
Image
Monoclonal Antibody Purification Guide
Optimize your antibody purification strategy with our antibody purification guide for selecting resins ideal for capture, intermediate, and polish.
