Enhancing the Quality and Consistency of Your AAV Vector Manufacturing
The push towards more targeted AAV vectors that allow dose reduction is not only about the biology of making the vector more efficient, but also about the manufacturing. The ability to identify, measure, and leverage the viral vector product’s critical quality attributes is central to the success of AAV-based gene therapies.
In this article, we discuss specific areas where innovation in analytical tools and techniques are providing valuable new insights into the quality and consistency of AAV vector manufacturing. We have collated advice from AAV developer industry leaders and the team at Cell & Gene Therapy Insights to provide you with a view into the role of analytical technologies to support the development of AAV-based gene therapies.
Read this article to learn how analytical technologies can address:
- Vector characterization and purity
- Viral genome titer
- Development of a functional AAV potency assay
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