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Quantifying AAV Viral Titers to Support AAV-Based Gene Therapy Development
Droplet Digital™ PCR (ddPCR™) can provide an absolute count of nucleic acids in a sample without using a standard curve. Learn how ddPCR technology offers the accuracy to quantify AAV viral titers to support many aspects of quality control for AAV-based gene therapy development. In addition to accurate measurement of AAV titer for proper dosing, ddPCR technology can detect other critical quality attributes, including residual host cell DNA and other contaminants.
What you will find in this article:
- A review of challenges and risks in the development of gene therapies
- How ddPCR technology can help developers of AAV-based therapies mitigate these risks
- Key references on the role of ddPCR technology in cell and gene therapy
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