Overview
The ddPLEX ESR1 Positive Control is a mixture of synthetic DNA consisting of all seven ESR1 variants and all wild-type targets covered by the ddPLEX ESR1 Mutation Detection Kit. The kit quantitatively detects seven key ESR1 variants across three exons: exon 5 (E380Q), exon 7 (S463P) and exon 8 (L536R, Y537C, Y537S, Y537N and D538G), and their wild-type counterparts.
The ddPLEX ESR1 Positive Control, in addition to verifying the performance of the reaction, serves as a guide for data thresholding, as it produces positive droplet clusters for each target. It is designed to resemble a sample with low input amount and low allele frequency. The Positive Control has sufficient volume for 12 reactions of both the Mutant and Wild-Type assays using the recommended input amounts.
The ddPLEX ESR1 Positive Control is a component of the ddPLEX ESR1 Mutation Detection Kit (17009501).
Product Contents
One vial containing 100 µl of ddPLEX ESR1 Positive Control.
Configuration Options
ddPLEX ESR1 Mutation Detection Kit
| Description | Catalog Number |
|---|---|
| ddPLEX ESR1 Mutation Detection Kit (120 reactions) ddPLEX ESR1 Mutation Detection Assay ddPLEX ESR1 Positive Control ddPCR Multiplex Supermix Dithiothreitol (DTT) |
17009501 |
Other Components from the ddPLEX Mutation Detection Kit
| ddPLEX ESR1 Mutation Detection Assay (120 reactions) | 12019648 |
| ddPCR Multiplex Supermix, 1.2 ml | 12005909 |
| Dithiothreitol (DTT), 2 ml | 12012171 |
Software Compatibility
ddPLEX ESR1 Mutation Detection Kit is compatible with the following QX Software selections:
| SKU Number | Product Name |
|---|---|
| Free download | QX Manager Software, Standard Edition |
| 12018108 | QX Manager Software, Premium Edition |
Related Category
Supporting Documents
For Research Use Only. Not for use in diagnostic procedures.