Overview
The VARIANTnbs System is designed for high-capacity screening and walk-away automation, reducing labor requirements and human error. Load up to three systems per workstation and up to 1,128 samples per run.
The VARIANTnbs System features fully automated analysis and advanced result "pattern" reporting for maximum efficiency. Using dried blood spot specimens, it detects hemoglobins (F, A, S, D, C, E) that are clinically significant for identifying:
- Hemoglobin disorders
- Carrier status for abnormal hemoglobins
- Double heterozygous conditions
- Hemoglobin Barts flagged as FAB
The VARIANTnbs System provides the total hemoglobin picture
The system is efficient and easy to use. Smart reports with optional pattern rules simplify data review while providing objective, accurate results. A flexible worklist import function eliminates file incompatibility issues. Reviewing and managing results is simple with electronic chromatogram storage and retrieval.
Educational Resources
Bio-Rad believes in sharing knowledge. We’ve created dedicated resources to help you strengthen your hemoglobinopathy expertise.
Library of Variants
In this digital database, find case reports to support the interpretation of hemoglobin variant chromatograms for sickle cell disease, thalassemia, and other hemoglobinopathies. Access this invaluable resource tool for your next case.
Test Your Knowledge
In this series of educational case studies, learn how to evaluate hemoglobinopathies and sickle cell cases and expand your knowledge of HPLC chromatograms.
Specifications
- VARIANTnbs System has two modules: Chromatography Station
- Left side of VNCS: 15 cm (6 in.)
- Back: 10 cm (4 in.)
- Right side of VNAS: 15 cm (6 in.)
- Top: 5 cm above open instrument cover Ensure the VNAS and VNCS are no more than 11.5 cm (4.5 in.) apart.
(VNCS) and Automatic Sampler (VNAS).Clearance for the system is:
- Dimensions (H x W x D):
- VNCS: 53.2 x 27.2 x 40.7 cm (20.9 x 10.7 x 16.0 in.)
- VNAS: 26.4 x 47.0 x 44.0 cm (10.4 x 18.5 x 17.3 in.)
- Waste Tank: 33.0 x 30.5 x 15.2 cm (13 x 12 x 6 in.)
- Weight (uncrated):
- VNCS: ≤35 kg (77 lb)
- VNAS: ≤20 kg (44 lb) The bench or table should have a flat, level surface that is free from vibrations and is capable of supporting up to 90 kg (200 lb).
- Power Consumption:
- VNCS: 200 VA maximum (2 A maximum) = 682 BTU/hr
- VNAS: 150 VA maximum (at Cooling ON) = 512 BTU/hr
- Operating Environment:
- Ambient temperature 15-25°C
- Humidity 10-90%, non-condensing
- Storage Conditions:
- Temperature -20°C to 50°C
- Humidity 10-95%
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Instrument for newborn screening of hemoglobins S, F, A, C, D, and E, includes bar code reader for sample tracking
Accessories
Kits & Reagents
The Bio-Rad VARIANTnbs Sickle Cell Program offers a rapid 3-minute qualitative screen for the presence of hemoglobins F, A, S, D, C, and E in eluates of neonatal blood collected with one step sample preparation.
