Human MMP and TIMP Assays

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Human MMP & TIMP Assays

Overview

Available Bio-Plex Pro Human MMP and TIMP Assays
Matrix Metalloproteinase
(MMP) Analytes
9-Plex Panel
(171-AM001M)
Singleplex Sets
Bead Regions*
MMP-1 171-BM001M 43
MMP-2 171-BM002M 26
MMP-3 171-BM003M 45
MMP-7 171-BM004M 66
MMP-8 171-BM005M 37
MMP-9 171-BM006M 55
MMP-10 171-BM007M 62
MMP-12 171-BM008M 53
MMP-13 171-BM009M 47

Tissue Inhibitor of Matrix Metalloproteinase (TIMPs)
4-Plex Panel
(171-AM002M)
Bead Regions
TIMP-1 21
TIMP-2 64
TIMP-3 52
TIMP-4 35

* You can design an Express “You Mix” multiplex kit with any combination of the MMP analytes. Express assays are configured on www.bio-rad.com/assaybuilder and are delivered to you. You mix the coupled magnetic beads and detection antibodies prior to use.

MMP and TIMP Classifications
Collagenases Gelatinases Stromelysins
MMP-1
MMP-8
MMP-13
MMP-2
MMP-9
MMP-3
MMP-10
Metalloelastase Inhibitors Matrilysins
MMP-12 TIMP-1
TIMP-2
TIMP-3
TIMP-4
MMP-7
 
Bio-Plex® Multiplex Immunoassays Analyte Guide Summer 2016

Use the Bio-Plex analyte guide to explore our analyte offerings, find new assays, and review performance characteristics.

Download Interactive PDF

Bio-Plex® Technology and Applications

Bio-Plex Pro™ Human MMP and TIMP Assays include the only Luminex panel on the market enabling users to investigate 9 MMPs in one sample at a single dilution.


Read full description

Ordering Information


  • Description
  • Ordering
  • Accessories
  • Kits & Reagents
  • Documents

Description

Analytes in the MMP Panel

  • MMP-1
  • MMP-2
  • MMP-3
  • MMP-7
  • MMP-8
  • MMP-9
  • MMP-10
  • MMP-12
  • MMP-13

Analytes in the TIMP Panel

  • TIMP-1
  • TIMP-2
  • TIMP-3
  • TIMP-4

MMPs have many different functions and actions in the body, whereas TIMPs work to inhibit the actions of MMPs. Studying MMPs and their inhibitors, TIMPs, together can reveal disruptions in the balance of these two proteins, providing insights into disease states.

These immunoassays are built on magnetic beads to enable robust quantification of multiple proteins in human samples for research involving the conditions and disease pathways listed below:

Associated Research

  • Cancer
  • Autoimmune disease
  • Cardiovascular disease
  • Infectious disease
  • Neurology

Associated Pathways

  • Inflammation
  • Wound healing
  • Metastasis
  • Apoptosis
  • Angiogenesis
  • Tumor invasion

Key Features

  • Magnetic beads for simplified plate processing
  • Custom configurable ordering options
  • Single-level quality controls with lot-specific ranges
  • Assay quick guide to get you started right away
  • High-quality design for robust and reproducible measurements

Available Assay Formats

Instrument Compatibility

Compatible with these readers and wash stations:

More Information

To learn more about performance characteristics or how to set up your MMP and TIMP assays for optimal performance and sensitivity, refer to the documents listed below:

See how Bio-Plex Instruments and Assays benefit researchers studying heart disease, leukemia, melanoma, and other cancers.

Related Products

Bio-Plex Pro™ Human Inflammation Assays
For the first time, the key biomarkers of inflammation from the TNF superfamily proteins, IFN family proteins, Treg cytokines, and MMPs can be measured using a single multiplex kit. Bio-Plex Pro Human Inflammation Assays are available in larger 24-plex and 37-plex screening panels and a pathway-focused Treg 12-plex panel, along with singleplex and custom-configured assays.


Ordering

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list price. If the problem persists, please call customer service at or send an
email to

Bio-Plex Pro™ Human MMP Panel, 9-Plex

171AM001M
1 x 96-well, includes coupled magnetic beads, detection antibodies, standards, control, buffers, diluents, streptavidin-PE, 96-well plate, and sealing tape for the detection of 9 matrix metalloproteinases

This product is being discontinued soon. Please contact customer service for more information.

Accessories

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If you are placing an order, you may proceed with your order; the account price will be applied if it is lower than the
list price. If the problem persists, please call customer service at or send an
email to

Bio-Plex® Handheld Magnetic Washer

171020100
Includes magnetic washer and adjustment hex tools for use in manual wash steps for all Bio-Plex Magnetic Assays

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$945.00 
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Bio-Plex Pro™ Flat Bottom Plates

171025001
Pkg of 40, 96-well plate, for use with Bio-Plex Pro wash stations when using magnetic bead–based assays

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$282.00 
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Filter Plate

171304502
Pkg of 1, 96-well plate, with clear plastic lid and tray, for Bio-Plex Assays using the vacuum wash method, sealing tape not included

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$31.00 
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Bio-Plex Pro™ Wash Station

30034376
Microplate wash station for magnetic bead–based assays, includes magnetic plate carrier, waste bottle, 2 buffer bottles

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Kits & Reagents

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(Discontinued) Bio-Plex Pro™ Human MMP Standard

171DM0501
Pkg of 50 lot-matched vials, lyophilized mixture of 9 MMP analytes

This product is no longer available. Please contact technical support for more information on replacement product.
Bio-Plex Pro Reagent Kit III with Flat Bottom Plate, 1 x 96-well

171304090M
1 x 96-well, includes detection antibody diluent HB, standard diluent HB, sample diluent HB, assay buffer, wash buffer, streptavidin-PE, flat bottom plate, and sealing tape, for magnetic separation methods

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$450.00 
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Documents

Number Description Options
6335 Bio-Plex Multiplex Immunoassays Analyte Guide Click to download
6551 Bio-Plex Pro Human MMP and TIMP Assays Product Information Sheet, Rev B Click to download
10041639 Instruction Manual, Bio-Plex Pro Human MMP Assays, Rev A Click to download
10041640 Instruction Manual, Bio-Plex Pro Human TIMP Assays Click to download
10041637 Instruction Manual, Bio-Plex Pro Human MMP Assays Quick Guide, Rev A Click to download
10041638 Instruction Manual, Bio-Plex Pro Human TIMP Assays Quick Guide, Rev A Click to download

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