Human MMP and TIMP Assays

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Overview

Bio-Plex Pro™ Human MMP and TIMP Assays include the only Luminex panel on the market enabling users to investigate 9 MMPs in one sample at a single dilution.

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Description

Description

Analytes in the MMP Panel

  • MMP-1
  • MMP-2
  • MMP-3
  • MMP-7
  • MMP-8
  • MMP-9
  • MMP-10
  • MMP-12
  • MMP-13

Analytes in the TIMP Panel

  • TIMP-1
  • TIMP-2
  • TIMP-3
  • TIMP-4

MMPs have many different functions and actions in the body, whereas TIMPs work to inhibit the actions of MMPs. Studying MMPs and their inhibitors, TIMPs, together can reveal disruptions in the balance of these two proteins, providing insights into disease states.

These immunoassays are built on magnetic beads to enable robust quantification of multiple proteins in human samples for research involving the conditions and disease pathways listed below:

Associated Research

  • Cancer
  • Autoimmune disease
  • Cardiovascular disease
  • Infectious disease
  • Neurology

Associated Pathways

  • Inflammation
  • Wound healing
  • Metastasis
  • Apoptosis
  • Angiogenesis
  • Tumor invasion

Key Features

  • Magnetic beads for simplified plate processing
  • Custom configurable ordering options
  • Single-level quality controls with lot-specific ranges
  • Assay quick guide to get you started right away
  • High-quality design for robust and reproducible measurements

Available Assay Formats

Instrument Compatibility

Compatible with these readers and wash stations:

More Information

To learn more about performance characteristics or how to set up your MMP and TIMP assays for optimal performance and sensitivity, refer to the documents listed below:

See how Bio-Plex Instruments and Assays benefit researchers studying heart disease, leukemia, melanoma, and other cancers.

Related Products

Bio-Plex Pro™ Human Inflammation Assays
For the first time, the key biomarkers of inflammation from the TNF superfamily proteins, IFN family proteins, Treg cytokines, and MMPs can be measured using a single multiplex kit. Bio-Plex Pro Human Inflammation Assays are available in larger 24-plex and 37-plex screening panels and a pathway-focused Treg 12-plex panel, along with singleplex and custom-configured assays.

Ordering

Ordering

items

Use the filters below to refine results!

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171AM001M
1 x 96-well, includes coupled magnetic beads, detection antibodies, standards, control, buffers, diluents, streptavidin-PE, 96-well plate, and sealing tape for the detection of 9 matrix metalloproteinases

Accessories

Accessories

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171020100
Includes magnetic washer and adjustment hex tools for use in manual wash steps for all Bio-Plex Magnetic Assays
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171025001
Pkg of 40, 96-well plate, for use with Bio-Plex Pro wash stations when using magnetic bead–based assays
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(Discontinued) Filter Plate
171304502
Pkg of 1, 96-well plate, with clear plastic lid and tray, for Bio-Plex Assays using the vacuum wash method, sealing tape not included
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30034376
Microplate wash station for magnetic bead–based assays, includes magnetic plate carrier, waste bottle, 2 buffer bottles

Kits & Reagents

Kits & Reagents

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171DM0501
Pkg of 50 lot-matched vials, lyophilized mixture of 9 MMP analytes
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171304090M
1 x 96-well, includes detection antibody diluent HB, standard diluent HB, sample diluent HB, assay buffer, wash buffer, streptavidin-PE, flat bottom plate, and sealing tape, for magnetic separation methods

Documents

Documents

Number Description Options
6335
Bio-Plex Multiplex Immunoassays Analyte Guide
6551
Bio-Plex Pro Human MMP and TIMP Assays Product Information Sheet, Rev B
10041639
Instruction Manual, Bio-Plex Pro Human MMP Assays, Rev A
10041640
Instruction Manual, Bio-Plex Pro Human TIMP Assays
10041637
Instruction Manual, Bio-Plex Pro Human MMP Assays Quick Guide, Rev A
10041638
Instruction Manual, Bio-Plex Pro Human TIMP Assays Quick Guide, Rev A