Methylation-Specific Droplet Digital PCR to Study Immune Cell Subtypes


See how researchers in John Wiencke's laboratory at UCSF use Droplet Digital PCR to investigate aberrant gene methylation in their studies of the molecular subgroups of glioma, cancer arising from glial cells — the most common source of brain tumors. Droplet Digital PCR (ddPCR) technology enabled the Wiencke Lab to analyze archival blood samples, some up to 20 years old, from cancer patients and controls to characterize differentially methylated regions of genes involved in immune responses