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Forged To Fight: Using Metal Ions Against Tumors

Metal ions are critical regulators of diverse immune pathways. Indeed, their therapeutic potential has long been harnessed in the form of metallodrugs, including platinum-based chemotherapies. Recognition that metal ions regulate the immune system through interactions with molecules and cells has led to the proposal of metalloimmunotherapies, a new class of immunotherapies for the treatment of cancer and other immune-related diseases.

This webinar, presented by Xingwu Zhou from the Department of Pharmaceutical Sciences at the University of Michigan, explores the concept of metalloimmunotherapy. Xingwu Zhou will present his research focused on STING agonist development, explaining the current state-of-the-art in developing these agonists and how metallonanoparticles offer an exciting new opportunity in this field.

November
19

Wednesday
9:00 AM PT/12:00 PM ET
5:00 PM GMT/6:00 PM CET

Harnessing Metal Ions to Power the Immune System

In this webinar, you will learn:

  • About the preclinical and clinical landscapes for STING agonist development
  • How to design strategies for STING-activating metallonanoparticles
  • The challenges and potential solutions for targeting the cGAS-STING pathway

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Speaker

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portrait of Xingwu Zhou

Xingwu Zhou, BS, MS
University of Michigan

Xingwu Zhou holds two Bachelor of Science degrees: from Soochow University, Suzhou, China, and the University of Waterloo, Canada, in Nanomaterials and Nanotechnology and Materials and Nanosciences, respectively. In 2020, he achieved a Master of Science in Chemical Engineering at the University of California, Los Angeles before joining the University of Michigan, where he is currently studying for a PhD in Pharmaceutical Sciences. Working with Dr. James J. Moon, the focus of his research is on the development of metalloimmunotherapies, a new class of immunotherapies that rely on the interaction of metal ions to modulate immune responses.

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