Ion-Exchange HPLC Systems: Hemoglobinopathy Testing Systems

  • The Choice of Experts

    Bio-Rad offers clinical diagnostic laboratories and blood donor laboratories a complete range of infectious disease testing systems, reagents and quality controls to optimize testing workflows and provide quality results.

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Our Commitment to Hemoglobinopathy Testing

In addition to being the choice of experts for over 25 years, Bio-Rad is committed to raising awareness about hemoglobinopathies like thalassemia and sickle cell to supporting prevention, awareness, and population screening programs. Bio-Rad believes in sharing our knowledge and has dedicated resources to build and maintain a digital database of hemoglobin variant case studies.

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  • variant II

    VARIANT II

    A reference HPLC system used in many laboratories for the analysis of normal hemoglobins and as an aid in the identification of abnormal hemoglobins.

  • d-10

    D-10

    Compact, fully automated HPLC system allows small laboratories to test with an easy switch: HbA1c and β-thalassemia.

  • variant nbs

    VARIANT nbs

    Established worldwide standard in automated newborn screening for sickle cell disease.

 
library of variants

The First Reference Library of Shared HPLC Cases

The Bio-Rad Library of Variants contains case reports of hemoglobin variants provided by a select group of reference centers within the worldwide community of laboratories actively working on detection of sickle cell, thalassemia, and other hemoglobinopathies.

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Hemoglobinopathy Testing Systems

Bio-Rad hemoglobinopathy testing systems have been the choice of experts for over 25 years. We will continue to partner with experts in this field to advance technology and patient care.

variants

VARIANT II Beta-Thal Short

VARIANT II Beta-Thal Short Program is an icon in β-thalassemia testing. After more than 25 years it is still the method of choice for expert reference centers. It is used for quantification of HbA2 and HbF and as an aid in the identification of common hemoglobin variants: HbS, HbC, HbD, and HbE.

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variant II dual program

VARIANT II Dual Program

The VARIANT II Dual Program* is for diabetes and thalassemia testing without the need for changing the column or buffers.

The extended method of the Dual Program is considered by many as an alternative to the VARIANT II β-thalassemia Short Program.

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variant II testing system

VARIANT II Testing System

For full automation and breadth of menu, choose the VARIANT II Hemoglobin Testing System. This multi-analyte system offers a β-thalassemia Program as well as a Dual Program with short and extended modes of operation requiring no change of column or buffers. The VARIANT II menu also includes HbA1c for diabetes testing.

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d-10 program

D-10 Dual Program HbA2/F/A1c

D-10 Dual Program for diabetes and thalassemia testing is an all in one kit for use on a small, compact, fully automated analyzer.

The extended method of the Dual Program allows accurate quantification of HbF, HbA1c and HbA2 along with detection of common hemoglobin variants: HbS, HbC, HbD, and HbE.

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d-10 testing system

D-10 Hemoglobin Testing System

For full automation, comprehensive menu and a small footprint, choose the D-10 Hemoglobin Testing System. The D-10 System offers a Dual Program for HbA1c and β-thalassemia testing with short and extended modes of operation requiring no change of cartridge or buffers.

For added throughput, the D-10 Rack Loader expands the D-10 System sample capacity from 10 to 50 samples per run.

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variant nbs program

VARIANT nbs Sickle Cell Program

VARIANT nbs Sickle Cell Program is a reference HPLC method with high resolution hemoglobin variant screening (HbS, HbC, HbD, HbE), that also provides smart reports with presumptive pattern identification.

The use of FADC/FAES controls increases confidence in normal and clinically significant hemoglobin variant detection.

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variant nbs newborn screening system

VARIANT nbs Newborn Screening System

The VARIANT nbs System is the established worldwide standard in automated newborn screening for sickle cell disease. With the VARIANT nbs System you get the total picture the first time allowing each baby to quickly receive the appropriate care and follow-up to alleviate parental concern.

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Disclaimer

*The VARIANT II Dual Program is not available for sale in the U.S.