Gene:  TRAF2, Human

print
PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

Why PrimePCR?

PrimePCR
Lookup Tool
Design and Validation of Real-Time PCR Primers
Pathway Curation
Control and Reference Assays for Real-Time PCR

The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with and mediate the signal transduction from members of the TNF receptor superfamily. This protein directly interacts with TNF receptors and forms a heterodimeric complex with TRAF1. This protein is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF1 interacts with the inhibitor-of-apoptosis proteins (IAPs) and functions as a mediator of the anti-apoptotic signals from TNF receptors. The interaction of this protein with TRADD a TNF receptor associated apoptotic signal transducer ensures the recruitment of IAPs for the direct inhibition of caspase activation. BIRC2/c-IAP1 an apoptosis inhibitor possessing ubiquitin ligase activity can unbiquitinate and induce the degradation of this protein and thus potentiate TNF-induced apoptosis. Multiple alternatively spliced transcript variants have been found for this gene but the biological validity of only one transcript has been determined. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: TRAF2, Human
TNF receptor-associated factor 2

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0010874
Info:   Same primer pair as used in probe assay qHsaCIP0027765
List Price:   
Your Price:   Log In
Quantity:  
 
Add to Custom Plate
PrimePCR™ Probe Assay: TRAF2, Human
TNF receptor-associated factor 2

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0027765
List Price:   
Your Price:   Log In
Quantity:  
 
Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
Get Help

Call us at 1-800-4-BIORAD (1-800-424-6723)

Sign Up for Bio-Rad Updates!
Enter your email address below to receive your choice of the latest news, promotions, and more.