Gene:  RAP1GAP, Human

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This gene encodes a type of GTPase-activating-protein (GAP) that down-regulates the activity of the ras-related RAP1 protein. RAP1 acts as a molecular switch by cycling between an inactive GDP-bound form and an active GTP-bound form. The product of this gene RAP1GAP promotes the hydrolysis of bound GTP and hence returns RAP1 to the inactive state whereas other proteins guanine nucleotide exchange factors (GEFs) act as RAP1 activators by facilitating the conversion of RAP1 from the GDP- to the GTP-bound form. In general ras subfamily proteins such as RAP1 play key roles in receptor-linked signaling pathways that control cell growth and differentiation. RAP1 plays a role in diverse processes such as cell proliferation adhesion differentiation and embryogenesis. Alternative splicing results in multiple transcript variants encoding distinct proteins. [provided by RefSeq Aug 2011]

PrimePCR™ SYBR® Green Assay: RAP1GAP, Human
RAP1 GTPase activating protein

Assay Type: SYBR® Green
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0003852
Info:   Same primer pair as used in probe assay qHsaCEP0024849
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PrimePCR™ Probe Assay: RAP1GAP, Human
RAP1 GTPase activating protein

Assay Type: Probe
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0024849
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Number Description Download
6262 PrimePCR Assays: Meeting the MIQE Guidelines by Full Wet-Lab Validation, Rev B Click to download
6263 PrimePCR Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy, Rev B Click to download
6290 PrimePCR Assays and Panels Brochure, Rev D Click to download
LIT10026370 Instruction Manual, PrimePCR Assays, Panels, and Controls, Rev E Click to download
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